Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RPS6KB1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
PHLPP1 AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17386267 15808505
AKT1 PHLPP2 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17386267 15808505
PTEN AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10644997
PHLPP1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21986499
PHLPP2 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21986499
AKT3 AKT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKT3 FKBP5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PHLPP2 USP12 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PHLPP2 WDR48 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
AKT2 AKT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 11546794 11278835 12149249 14500673 9736715 12176337 28514442 11445557
SLC9A3R1 EZR â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 11285285 5213905
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RDX SLC9A3R1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PTEN SLC9A3R1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RPL3 RPS11 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
AKTIP AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 14749367
WDR20 WDR48 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AKT2 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23431053
AKT3 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23431053
NR1I2 PHLPP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
NR1I2 WDR48 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
PHLPP1 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18162466
PHLPP2 PRKCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18162466
PHLPP2 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18162466
PHLPP2 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20513427
EZR SLC9A3R1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
USP12 WDR20 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
USP46 WDR20 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
AKT1 STK4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
RPL3 RPS11 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
USP12 WDR48 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
USP1 WDR48 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
USP46 WDR48 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
PHLPP1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18511290 15899889 20576936 19797085 17386267 15808505 19261608
PHLPP2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18511290 15899889 19797085 17386267 15808505 19261608
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11943559 23331499 25241761 21071413 12183455 15149849 11438723
PHLPP2 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17386267 19261608
PHLPP1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20576936 17386267 11507039 15808505 19261608
AKT2 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14504278 15531580 10970850 11387207 15843435
PHLPP1 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9512493 17386267 19261608
PHLPP2 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9512493 17386267 19261608
SLC9A3R1 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11285285 20937695 11684085 9314537 15020681 23414517
PRKCA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 14504278 15531580 10970850 11387207 21899702 15843435 9516463 15647376
FANCD2 FANCI â—¼   PHYSICAL_INTERACTION 66.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14614141 14624239 14726013 15242590 15375219 15377654 15459660 15485915 15703371 16337601 16337602 16697054 16713580 16818604 17303408 17349954 17965729 18082604 18082605 18085520 18087292 18448394 18472307 18543256 18584027 18809224 18931676 18995830 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20064462 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 FANCI â—¼   SHARES_COMPLEX 66.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14614141 14624239 14726013 15242590 15375219 15377654 15459660 15485915 15703371 16337601 16337602 16697054 16713580 16818604 17303408 17349954 17965729 18082604 18082605 18085520 18087292 18448394 18472307 18543256 18584027 18809224 18931676 18995830 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20064462 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
USP1 FANCD2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
USP1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19264559 19686080 18082604 23589330 36170365 19622404 19075014 16633336 18082605 19217432 18931676 15694335
FANCI FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21719678 22855611 24451376 17460694 27773793 20603015 25168188 19561358 18931676 24623813
WDR48 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19264559 19686080 18082604 23589330 19622404 19075014 18082605 19217432 18931676
USP1 FANCI â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
USP1 FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19264559 19686080 18082604 23589330 17488615 19622404 19075014 18082605 18985065 19217432 18931676
WDR48 FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19264559 19686080 18082604 23589330 35703356 19622404 19075014 18082605 19217432 18931676
PHLPP1 PRKCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18162466
PHLPP1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513427 23431053
PRKCA SLC9A3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17613530 20571032 12881487
SLC9A3R1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23118026 16456542 21990315 24012959
WDR48 USP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32951278 18082604 34128540 23116119 23463011