GRB2
|
ACKR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ACKR3
|
CXCL12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9618518
16107333
|
FOXO1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15059979
15632117
|
JUNB
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11163237
|
BCL2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15210690
|
FOXO1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15059979
10871843
|
JUNB
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11163237
|
EZH2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20132185
21697275
|
EGFR
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7945309
|
CDKN1A
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
AKT1
|
CDKN1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12244303
11231573
|
EGFR
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
JUNB
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12791272
|
EGFR
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
EP300
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
FOXO1
|
CCL20
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25918228
22240809
|
FOXO1
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20338229
15632117
|
FOXO1
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19651810
22240809
|
FOXO1
|
BMP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15688035
16100571
|
CREBBP
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10973497
|
CCR10
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
EPO
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
CNTFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
IL5RA
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
IL2RB
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
10602027
|
SNTA1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11551227
11278583
|
IL1R2
|
IL1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16971486
0603545103
|
IL1A
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16971486
0603545103
|
IL1A
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2946959
8327496
|
REL
|
IL1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17513725
23195252
|
NFATC2
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23858296
22333584
|
MYC
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21925595
23722468
|
MYC
|
EZH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21941025
19197161
|
MYC
|
CD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1321339
11266125
|
MYC
|
HLA-DRB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17881904
18544564
|
AKT1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17942906
9804616
|
NFATC2
|
FOXP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17377532
16873067
|
NFATC2
|
IL31
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25595785
22045870
|
NFATC2
|
IL2RA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17463169
9763616
|
NFATC2
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8530342
15314684
|
NFATC2
|
IL17A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22989874
15459204
|
NFATC2
|
IL21
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15684054
15879595
|
NFATC2
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17079331
|
NFATC2
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26903200
20424162
|
CCL3
|
CXCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9312096
11470772
|
CCL21
|
CCR7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8383238
7851893
|
BMP10
|
ACVRL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17068149
17311849
|
IL1R1
|
IL1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221365
9062193
|
CISH
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD2
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD2
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14500551
12853969
|
FOXP3
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19797626
24315995
|
EZH2
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19687301
16007202
|
FOXP3
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20554955
21746966
|
IL4R
|
IL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10219247
5211389
|
IL2RA
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
IL2RB
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
EBI3
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22306691
12829785
|
IL27RA
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
24743305
24572363
|
IFNE
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22410872
32196115
|
IL36G
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17208301
23331499
|
IL2RA
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0607058103
17032757
|
JAK3
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
CREBBP
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
REL
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15048722
21890374
|
GATA1
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15739164
21454593
|
IL10RB
|
IFNL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
IL10RB
|
IFNL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
CD4
|
HLA-DRA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQB1
|
CD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
11535811
|
HLA-DPA1
|
CD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12899833
16189514
|
RBPJ
|
FOXP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18777163
24478388
|
CISH
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12586763
10585430
|
IL36G
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17208301
23331499
|
IFNE
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22410872
32196115
|
HLA-DRA
|
HLA-DQA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DRA
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
IL22
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17208301
23331499
|
ACVR2B
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
RBPJ
|
FHL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17509614
9418910
|
CXCL11
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22633458
15178708
|
REL
|
IL12A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16166378
|
IL2RA
|
JAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
ACVR2B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
BMP8B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
ACVR2A
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9748228
8612709
|
IL11
|
IL6ST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7957045
8637716
|
BMPR1A
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMP8B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
IL12A
|
IL6ST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22306691
12829785
|
IL6ST
|
CTF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2779549
15519241
|
IL6ST
|
IL11RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7957045
8637716
|
IL6ST
|
EBI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22306691
12829785
|
IL6ST
|
CLCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12707266
7852997
|
JUNB
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11509003
25861992
|
IFNLR1
|
IFNL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
IFNLR1
|
IFNL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
EDA
|
EDA2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14656435
10484778
|
HLA-DQB1
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11376336
5214072
|
HLA-DQA2
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQB1
|
HLA-DQA1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
HLA-DQA2
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
EPOR
|
EPO
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
IL1RN
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1828071
2139180
|
IL23A
|
IL12B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
IL12A
|
IL27RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
24743305
24572363
|
CCL1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11470772
10910894
|
CCL18
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23951310
32103204
|
CCR3
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CCR6
|
CCL20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9169459
12149255
|
BMP6
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
CNTFR
|
CLCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21715184
10966616
|
CCR2
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CX3CR1
|
CX3CL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9024663
9390561
|
IL24
|
IFNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18511292
|
IL1F10
|
IL1RL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
26892022
22315422
|
CCL25
|
CCR9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10229797
10640743
|
IL17C
|
IL17RE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21993848
21993849
|
ACKR3
|
CXCR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
EP300
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
JUNB
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
15308641
17510411
21937452
|
CREBBP
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
IL3RA
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17474147
7523859
|
CSF2
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
11468284
9187659
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IFNA4
|
IFNA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IFNA4
|
IFNA8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IFNA4
|
IFNA7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ACVRL1
|
BMP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
HLA-DQA2
|
HLA-DQB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
IFNA5
|
IFNA6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCR5
|
CCL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9334377
10477718
10498628
8663314
23597562
12427015
9468473
|
JAK3
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
10506573
|
CSF3
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16492764
10364174
|
IFNA2
|
IFNA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IFNA5
|
IFNA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AKT1
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
31575057
|
CCND1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
IFNL3
|
IL10RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
IL21
|
IL21R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
IL1B
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CISH
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
10514520
|
HLA-DRB1
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
5220278
7477400
|
CDKN1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
IL12B
|
IL23R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
FOXP3
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
IL2RB
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
10602027
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
IFNL3
|
IFNLR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
12469119
|
IL22RA1
|
IL22
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
18675809
6693914
|
AKT1
|
FOXO1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
21798082
|
AKT1
|
FOXO1
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
18423396
|
EP300
|
FOXO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15890677
24419059
25609649
18786403
11896584
|
CCR3
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8642344
10733106
|
CCR4
|
CCL22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9743322
9933589
9430724
|
CCR4
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8573157
12270118
|
AKT1
|
SMAD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16362038
24412244
|
AKT1
|
FAS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25640309
31980649
|
IL2RA
|
IL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17032757
16477002
1993646
|
CCL23
|
CCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9886417
9558365
10660125
|
ACVR2B
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CCL5
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
MYC
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15616592
16287840
32140074
16126174
17157259
12776737
|
AKT1
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21901101
15224190
21775285
20333651
18182168
11116148
|
GHR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17474147
9632636
|
CCR1
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8530354
7545673
9336350
|
CCR5
|
CCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9334377
10477718
9169459
11700073
9468473
|
CXCL9
|
CXCR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9660793
11259614
12782716
9625760
|
CCR3
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
10733106
8642344
7622448
9289016
|
CCR1
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
12270118
8530354
7545673
14637022
11116158
7622448
9115216
9289016
10910894
9336350
|
EDAR
|
EDA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11309369
11035039
|
BCL2
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
FAS
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ACVR2B
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
IL6
|
IL6ST
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
8511589
|
IFNA14
|
IFNA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
IL20RB
|
IL22RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EP300
|
CCND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15951563
10567390
11788592
|
EP300
|
SMAD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11371641
21988832
10199400
12237408
11264182
15623506
|
IL1R1
|
IL1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7878046
9062193
|
CD4
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10816381
15660419
14592831
|
CSF1R
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CISH
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
CREBBP
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
AKT1
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
EPOR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
7534299
9129019
8647802
|
SNTA1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11551227
11278583
|
CSF3R
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9824671
14557262
17001306
|
IL3RA
|
IL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9278420
7957082
8649415
|
CCR5
|
CD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10816381
30542158
15660419
|
GHR
|
CISH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10585430
12586763
25505247
|
CSF1R
|
IL34
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22483114
23478061
|
BMPR1A
|
GDF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
ACVR2A
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
IL1RN
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
2876877
|
FOXO1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
22266855
12391153
|
CISH
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24658140
16273093
25402006
31980649
|
JUNB
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10803405
23455325
|
FOXO1
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12391153
15613482
|
EPOR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8647802
16713569
7534299
|
SMAD2
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11804592
28628118
28205554
|
RBPJ
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18490439
10644343
16847353
|
MYC
|
CXCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
IL11RA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16846534
16489011
18562319
|
MYC
|
CXCR4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10229837
11145693
|
MYC
|
CCL14
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
BMP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
NFATC2
|
FOXP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25126782
16517728
17463169
|
NFATC2
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8668213
22911897
10330159
|
CXCR1
|
CXCL6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1840701
3260265
9164944
|
CCR7
|
CCL19
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11698286
17035340
19759904
|
CCR7
|
CCL19
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11698286
17035340
19759904
|
CCL16
|
CCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCL16
|
CCR8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCL16
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
REL
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11160303
|
ACVR1B
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11024047
12063393
14978253
|
CCR5
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11449371
10477718
10488147
9334377
8663314
14637022
9207005
11116158
9289016
|
IL15
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
25416956
23104097
10903799
9176231
8026467
|
IL2
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11035066
16477002
8049354
8006584
22446627
|
IL15RA
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17709786
15265897
7641685
|
IL12A
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
IL12B
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
IL12RB1
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
IL6ST
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
24743305
22306691
12829785
|
CREBBP
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17923090
|
IFNK
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17208301
23331499
22410872
|
EZH2
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24108699
21624129
16009709
|
IL10RB
|
IFNL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12469119
21716315
23291588
|
IL10RB
|
IFNLR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12469119
21716315
23291588
|
IL10RB
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12483210
23331499
12974481
|
CSF1R
|
CSF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26235028
2408759
22483114
8355686
22153499
22902366
|
CSF1
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16492764
23331499
|
CSF1
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
CCR5
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12429730
15660419
18632580
|
CISH
|
EPOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11781573
16961462
9774439
7796808
15644415
28038963
|
CSF3
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
IL37
|
IL18R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12096920
25654981
|
IFNK
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17208301
23331499
22410872
|
JAK3
|
IL21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11418623
11016959
12093291
|
IL12A
|
IL12RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
IL12B
|
IL12RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
HLA-DRA
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DRA
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DRA
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
IL24
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12351624
22802649
11706020
|
IL20RB
|
IL20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11163236
22802649
12351624
|
JAK3
|
IL21R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11418623
11016959
12093291
|
IL21R
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
12093291
|
AMHR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
14746809
16446785
|
GDF11
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12414726
|
ACVR2A
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12682303
9032295
8612709
|
ACVR2B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
17295905
16446785
|
IL6ST
|
IL27RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14764690
27119567
24771852
|
EBI3
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22306691
28280243
|
IL5RA
|
IL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7721873
22153509
10823900
7957082
1495999
1732409
10880230
|
CCR3
|
CCL11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8676064
10733106
9169459
9712872
9207005
8642344
25450766
8609214
23597562
|
HLA-DQA2
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DQA2
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
EPOR
|
EPO
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
9030560
29997244
9808045
17327410
9774108
26481148
15358619
10318834
8662939
|
GATA1
|
CCR3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22217447
21041734
|
IL23A
|
IL12B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29997244
12023369
11114383
18680750
|
IL12B
|
IL12A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10899108
10779781
7527811
|
IL12A
|
EBI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22487722
18033300
9342359
|
IL24
|
IL20RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12351624
22802649
11706020
|
CCL13
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10699158
23846739
|
CLCF1
|
CNTFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26858303
11285233
10966616
11294841
|
CCR10
|
CCL27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
CCR10
|
CCL28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
IL1RL2
|
IL36G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11466363
22315422
25673295
|
IL1RL2
|
IL36B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11466363
22315422
25673295
|
IL36RN
|
IL1RL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20081871
20959797
24332029
|
IL17RE
|
IL17C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23834281
21993849
21993848
|
HLA-DMA
|
HLA-DRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
IL6R
|
IL6ST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
EPO
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
GDF2
|
ACVRL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
17068149
|
CCND2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
HLA-DPA1
|
HLA-DPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
IL34
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
24890514
|
IL11
|
IL11RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CCL19
|
CCR7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
9153236
9507024
|
BMP4
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHOSPHORYLATION
|
|
|
0.92
|
0.92
|
Signor
|
11726515
|
IL23A
|
IL23R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
IFNAR2
|
IFNW1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
IL13RA1
|
IL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
IL20RA
|
IL20RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
IL20
|
IL20RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
CCND3
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
FHL1
|
RBPJ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CD40
|
CD40LG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL15RA
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CSF3
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IFNAR1
|
IFNW1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL20
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IFNL1
|
IFNLR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL1R1
|
IL1RN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
IL13RA1
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
IL1R2
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ACVR2B
|
GDF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
IL1B
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
CCL20
|
CCR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
10488147
10498628
9169459
9223454
9294137
|
ACVRL1
|
GDF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
FOXP3
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
IL1RAP
|
IL1RL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
IFNAR1
|
IFNAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
HLA-DMA
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
CDKN1A
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
16765349
5218735
|
AKT1
|
FOXO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
10358075
25241761
10358014
16076959
31844113
18786403
|
IL12A
|
IL12B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
ACVR2A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CSH1
|
CSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
CSF1R
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10025673
8262059
7597091
9380408
9178909
|
HLA-DRA
|
HLA-DRB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
HLA-DMB
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
CRLF2
|
IL7R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
IFNA2
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19254954
7518560
31980649
9416834
7592693
23956138
14679214
10085134
7510700
27059931
21706016
25402006
16799092
16729043
8665853
15657067
24797263
12577067
8810325
7650032
11960376
23799367
25187647
8626525
10026169
19289468
18271526
21278786
7506413
17971399
8940013
20124286
11726515
9886492
10595738
24189400
9020117
19531499
20473329
9020193
8662998
8647858
1322798
8887653
10229072
16273093
25754235
31959764
11370743
16713569
21596750
9685397
24658140
31985874
22973453
11896612
20067773
17242169
19836242
8810340
21278788
30544639
7527043
9050991
11408594
8621459
|
BMPR1A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
19804412
7261592
|
IL5
|
IL5RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
GH1
|
GHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CCL5
|
CCR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IFNA2
|
IFNAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IL1B
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IL12B
|
IL23A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IL6
|
IL6ST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CCL11
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
IL22
|
IL22RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CCR5
|
CD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
CSF1R
|
IL34
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
HLA-DMA
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
GRB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
CCND1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
BMP2
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
HLA-DRA
|
HLA-DRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
HLA-DQA1
|
HLA-DQB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CXCL12
|
ACKR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23396314
20956518
24218476
16107333
22633458
20161793
|
CXCL11
|
ACKR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
29386406
29180449
27875312
24218476
22633458
16940167
20161793
|
BCL2
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11463391
11463392
11532940
11704864
12566895
12667443
14764585
15516985
17446862
19289794
19565474
22039431
23064052
23377657
23430059
23850759
24027568
8929532
9069260
9872359
|
MYC
|
BCL2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
MYC
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8036017
17404573
12695333
24167291
18809243
19201832
16316993
19649202
|
BCL2L1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18835031
14980220
26186194
11583631
|
AKT1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
CREBBP
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9829964
10753867
17565603
15337521
10454566
|
AKT3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
GATA1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17420275
10381501
|
MYC
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
14517295
18802399
16316993
17331788
|
AKT1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
MYC
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7526316
21933022
17881732
12835716
14757441
19086036
8552398
19698176
19786833
18809243
18806825
8196642
11085504
|
JUNB
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15706412
10790372
11402335
20200942
|
EP300
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17306568
17666529
11788592
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
CDKN1A
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
26203195
23443559
17145710
25416956
7478582
9837900
21988832
21516116
7777546
15232106
16082198
27107012
15695403
8657154
8242751
23007395
9106657
12383116
17556661
8756624
8662825
31515488
|
MYC
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8425218
15121849
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
SMAD2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9618481
12200968
17516505
14762439
10506225
24052079
14583455
|
RBPJ
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11432830
11306509
15866158
14670925
|
EZH2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21572997
21546904
24074410
21629038
22956625
|
MYC
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15190211
14519204
15616584
12408868
19174556
21949397
10319992
12553001
16204065
12545156
20878079
21042278
21400515
20190815
16706751
23804320
15757889
10920185
19270520
16452181
12408820
15528212
22371483
12565816
17885207
12384701
11274368
19150257
20551174
15899785
21120446
15071503
15474507
22814619
12835716
12748190
16738884
15711923
18636159
|
FOXO1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17609436
23574718
23918930
24769335
|
EP300
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10362258
15509808
21858218
22000024
21245169
|
AKT3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12851486
15023346
19216069
17680028
11756412
16680151
20214616
11463845
23109003
20452955
9829964
20398329
17646672
10217147
|
AKT2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
21933447
16982699
20452955
9829964
20398329
17646672
10217147
|
MYC
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15528212
9618481
12545156
17550342
10454538
15155580
11283613
10920185
11283614
|
SMAD2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9389648
9618481
12545156
17550342
11013220
15155580
9670020
11074002
11283614
|
AKT1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20452955
27603133
20398329
18372248
15001356
15808505
10217147
19440234
20138985
12431783
10753973
17855660
19216069
28358423
20214616
11463845
9829964
17570479
17646672
16680151
11231573
15169778
12851486
31575057
25241761
23109003
21933447
10949026
16775416
23886938
26436589
16288292
11715018
16055744
18636226
15023346
9812896
12042314
17680028
24848107
16982699
11779850
10722653
20832730
18570873
20307683
34069970
17052453
15798220
|
FOXO1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15084259
19380174
21708191
15084260
21613825
17940099
11154281
|
CDKN1A
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
23443559
26186194
25241761
27107012
8756624
15169570
25416956
16765349
31515488
16189514
32296183
|
CDKN1A
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
21988832
23443559
26186194
25241761
27107012
8756624
25416956
16328436
31515488
16189514
15232106
32296183
23880157
26496610
9716181
|
CXCL12
|
CXCR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
24023874
10233851
10699158
11859124
22633458
18648536
18448868
8752280
30476826
12714578
16725153
9712844
8752281
9551924
21757744
19837984
25495026
26582643
16626895
|
CXCL12
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9660793
|
EGFR
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
EGFR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
9544989
10595738
23956138
27059931
10026169
16273093
11726515
24697349
21596750
19289468
7518560
21706016
23799367
9050991
16317285
16713569
25402006
11370743
24797263
8647858
8887653
9416834
21278786
16799092
8662998
10229072
11896612
7592693
19509291
8810325
24189400
19836242
11960376
7506413
18271526
15657067
10085134
24658140
17242169
7510700
8940013
7650032
8810340
11084343
12577067
7527043
31980649
11408594
19531499
20124286
23178716
9886492
23181695
9020117
8479540
14679214
12648464
1322798
17991782
16729043
17971399
|
IFNG
|
EP300
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
AKT2
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17964260
16926151
|
AKT1
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17623675
18182168
16926151
20333651
19158375
17964260
17570479
11116148
25904863
21901101
23275565
16024795
|
EP300
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
21988832
23331499
9169454
12237408
10199400
11264182
7878020
8047140
12958365
19171760
11371641
16027720
17074756
17469772
21269274
15623506
|
EP300
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17306568
17666529
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
AKT1
|
FOXO1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
15987244
10358075
10102273
12857750
|
FOXO1
|
IL7R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21532575
19285438
19136962
18978794
|
FOXO1
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16006742
15632117
12482965
19690465
14576824
12172378
|
AKT1
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
90.0
|
1.0
|
Omnipath
|
21440011
10358014
11756412
10358076
31308176
20452955
21798082
11410590
20398329
11311120
11544290
28279977
10217147
15132996
23331499
19216069
11237865
20214616
11463845
16076959
11030146
12228231
9829964
18951090
23180781
17570479
10102273
18593906
17646672
16680151
12456685
18423396
18985696
18988627
17962350
30728292
16670091
18786403
14664696
25241761
16341064
11980723
10358075
2984676
13679577
12560069
10377430
11251083
17680028
2987962
17254970
11864996
20041807
|
AKT2
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
17646672
20214616
11463845
20705244
20452955
9829964
20398329
10102273
18593906
16680151
10377430
10217147
|
AKT3
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
17646672
20214616
11463845
20452955
9829964
20398329
10102273
18593906
16680151
10217147
|
FOXO1
|
FASLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10783894
20673124
11094066
10102273
15668399
17646672
11994454
|
HRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
GRB2
|
CXCL8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
IL6ST
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7963520
9013873
|
CSF1R
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9178909
9380408
10025673
8262059
|
GRB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17496910
16713569
17673906
11352655
|
IL15
|
IL1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL1A
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
25241761
16971486
7878046
1833184
9862719
23395675
78780467878046
|
IL1A
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
23331499
29469592946959
8142597
19479203
7692435
9565970
7775431
2946959
17507369
7964161
|
IL1A
|
IL1RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9820540
9862719
7775431
17507369
|
GATA1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24336126
19522008
12832487
|
MYC
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
14563113
20101459
20155283
12655294
14519204
10734130
11050389
15302589
|
MYC
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7526316
11511535
10508165
9339900
15988028
20857481
11060032
14519204
14660677
10956386
21790895
11264343
|
MYC
|
JUNB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
2123531
7775604
12695333
18838534
18414489
|
MYC
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8962093
10702306
12695333
1349016
9417120
|
CREBBP
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
15522869
12776737
20144767
17660363
16878156
15279786
|
MYC
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8425218
15121849
11602341
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
MYC
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
11804592
|
NFATC2
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21799768
12452838
9399698
17687519
18217957
|
NFATC2
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17237447
18719603
|
NFATC2
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
11781715
15684054
11687571
22226971
23612709
19915002
9916709
7989759
12218118
9430230
15048722
8524816
10069428
11956291
10772943
10894164
12355451
12594266
17645498
8668213
25037220
21799768
18962896
9845517
9133600
8284217
9310836
18217957
15539155
|
NFATC2
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
15180435
20557936
8576111
8014029
8397339
7706710
21458306
21832163
8577772
17513763
16873067
8631809
11956291
12560487
17237447
24561192
18097033
7565732
8668213
7982959
21799768
8441422
9047239
8098881
1712901
|
NFATC2
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23616576
18962896
15684054
12836278
22123848
11520798
12842891
18217957
22427656
22844476
10894164
21624129
16237086
|
NFATC2
|
CD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21799768
10692237
17463169
16880206
16219537
9916709
10799559
|
CCL7
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
14991608
12381680
9115216
10699158
11994538
7545673
22633458
9336350
8530354
|
CCL7
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8642344
10733106
10699158
22633458
|
CCL7
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9276730
22633458
9115216
10699158
9346309
9195948
9312096
12554737
9336350
7759884
8530354
|
CCL7
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
10477718
16298345
10699158
22633458
10477710
|
CCL7
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
9364936
|
CCL7
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
9660793
|
CCL2
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10623817
15032599
17681149
19915063
23527025
23567181
23943801
24531940
27216177
|
CCL2
|
CCR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10623817
15032599
17681149
19915063
23527025
23567181
23943801
24531940
27216177
|
CSF1
|
CCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11306493
15749884
16713974
17404308
20547845
24669294
|
REL
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10614622
11716760
12218154
16325549
20038977
10469356
9388261
|
CCL2
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
10770925
10488147
10699158
22633458
9169459
11470772
28389721
9336350
8530354
15629146
11310855
9276730
20219869
9115216
9346309
9312096
9837883
10529171
15207250
9287323
12554737
7759884
|
CCL2
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9364936
10706668
|
CCL2
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8631787
7679328
76793288631787
9115216
10699158
|
CCL2
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8642344
|
CCL2
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10477718
16298345
1629834510477710
|
CCL2
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17160712
16421945
|
CXCL8
|
CXCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL8
|
CXCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL2
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8702798
9260277
16189514
1379593
12964882
|
CXCL6
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8702798
10699158
9485196
16189514
9692902
22633458
12964882
10593335
|
CXCL8
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
8702798
8137938
9195914
10699158
1840701
12628493
10188995
15946947
22262769
8550564
9553055
1379593
8662882
8245475
10368283
9485196
8940121
15282370
11350788
9725262
10206993
|
CXCL1
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8702798
9195914
10699158
16189514
1379593
12964882
|
CXCL3
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
129648828702798
8702798
16189514
12964882
|
CSF2
|
CXCL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
CXCL1
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
7592830
8702798
9195914
10699158
12628493
22633458
10188995
12549928
8550564
28389721
16189514
1379593
8662882
9126332
10216072
24218476
8940121
|
CCL3
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
11170631
10734056
10488147
10699158
7545673
10202040
22633458
10498628
9169459
9336350
10910894
8530354
23765404
9687537
9207005
20219869
9115216
9624164
10660125
7622448
12381680
|
CCL3
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8573157
|
CCL3
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24218476
7594543
7622448
|
CCL3
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
11170631
16298345
10477718
23765404
15075201
9468473
20219869
9169459
11700073
10699158
9334377
9790730
22633458
12964882
|
CCL21
|
CCR7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11970971
10488147
9507024
10699158
16713569
22633458
22221265
9585422
|
CCL21
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26888559
11907075
|
CCL21
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10706668
23341447
16713569
22633458
|
BMP10
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17068149
|
BMP10
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
30246251
30246252
27252362
31127068
|
CXCL9
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9660793
12782716
15761110
9625760
12750173
10699158
11259614
12884299
|
CXCL9
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
|
IFNA6
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA6
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
CCL4
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
7594543
12381680
10699158
7545673
10910894
8530354
|
CCL4
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7622448
|
CCL4
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10699158
9521068
|
CCL4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10498628
16298345
8663314
10477718
9468473
20219869
23597562
10699158
9334377
9790730
16467191
22633458
12427015
12964882
|
IFNA14
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA14
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
CCL19
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
|
CCL19
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10706668
23341447
16189514
22633458
|
CCL19
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CCL19
|
CCR7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10512740
9507024
15546958
10699158
9153236
24218476
22633458
11342595
16904643
|
FOXP3
|
CCR4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21036387
20554955
|
CCL22
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9933589
9430724
29637711
10699158
22633458
9743322
|
CCL17
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10498628
10488147
9169459
9430724
29637711
10699158
9169480
10540332
22633458
|
CCL5
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8573157
12270118
|
CXCL8
|
CXCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555777
18555778
18633355
18980965
21328342
21847358
23869868
24406209
25922287
26201938
27557510
|
CXCL8
|
CXCR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555777
18555778
18633355
18980965
21328342
21847358
23869868
24406209
25922287
26201938
27557510
|
CXCL6
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8702798
9485196
16189514
9692902
22633458
12964882
10593335
|
CXCL3
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
22633458
|
CXCL2
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8940121
8702798
9260277
8550564
10699158
16189514
1379593
22633458
10188995
12964882
|
CXCL8
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
70.0
|
1.0
|
Omnipath
|
7592830
8702798
22904195
9195914
10699158
7559482
12628493
23597562
10188995
15946947
8626516
8550564
9553055
1379593
8662882
19190236
8245475
9126332
10216072
1891716
9485196
8940121
15282370
9464567
11350788
11511101
9725262
10206993
|
CCL16
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11470772
22633458
10910894
|
CCL16
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
10910894
|
CD40LG
|
CD40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD40
|
â—¼ PROTEIN_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11581322
15034038
17200410
17371980
23125331
8760829
|
CD40LG
|
CD40
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
1280226
1374165
19426221
7516405
11163401
7543281
12324477
10647992
17183360
|
IL1R1
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
14660645
16878026
17704786
17942936
18977329
19104081
19161412
23202296
23681101
23811849
24727385
|
IL1R1
|
IL1RAP
|
â—¼ PROTEIN_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
14660645
16878026
17704786
17942936
18977329
19104081
19161412
23202296
23681101
23811849
24727385
|
IL1RAP
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15044087
23331499
15866876
9430229
10854325
11756486
9371760
7775431
12530978
17507369
|
IL1B
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17145710
23331499
8142597
9062193
7878046
9820540
7775431
2946959
24166242
9625767
|
IL1RN
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
20959797
17145710
8142597
2876877
24332029
7589429
11641511
9062194
|
IL18
|
SMAD2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
SMAD2
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
24.0
|
1.0
|
ACSN
|
10925299
11074002
11279127
11399519
11792802
11875494
12193690
12702545
12809600
15265520
15644117
16127449
16179589
16713975
17260466
17689680
21042762
21614932
22331441
23390297
6357187
8871614
9389648
9670020
|
CREBBP
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16751102
18003620
9679056
15750622
17283070
20403362
17074756
15231748
|
ACVR1B
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
9346908
11389842
9892009
18988627
14517293
|
IFNG
|
IFNGR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IFNGR2
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IL18RAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IFNG
|
IL18R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IL4
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IFNG
|
FOXP3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
FOXP3
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20554955
17028180
23543754
19877017
17377532
20308632
|
EZH2
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22563434
21674483
17911618
21624129
|
REL
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9374532
16481345
23195252
1542667
17012234
7957928
|
IFNG
|
IFNGR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
12915721
7673114
7514165
12438563
15530433
23331499
16237089
9111318
15143187
16467876
10986460
18988627
1396683
8550631
29145629
10811850
7617032
18591661
8631301
7615558
7510216
20304997
|
REL
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12820969
17705131
11259372
9120310
20058312
16707500
|
CCL5
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CCL5
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10734056
7622448
8642344
22633458
10733106
10699158
9289016
|
CCL5
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
10734056
7622448
14637022
22633458
9115216
9624164
10699158
11116158
12270118
7545673
9289016
9336350
10910894
8530354
|
CCL5
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
16298345
10488147
28381538
10699158
22633458
9289016
12213786
8663314
11449371
10318947
12964882
25923671
9207005
23480650
11116158
10477718
14637022
9334377
9790730
|
IL6
|
IL6R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
IL6
|
IL6R
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
IL15
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL6
|
IL6R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
REL
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17513725
17982049
11564778
11160296
1372388
19122653
12426000
9171095
8910763
16688168
|
JUNB
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20221401
11337499
12070012
7836389
10497240
19918056
8537375
|
IL6
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
14557255
19715447
3136546
12829785
18775332
7744001
8293462
15895091
11251120
2788034
1995637
|
IL6
|
IL6R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17145710
8702737
7744001
23663276
15895091
9028955
1995637
23331499
12829785
3136546
21071413
14656210
28265003
12643274
7893704
18923185
11238858
8706672
8676083
18067990
2788034
14557255
18775332
9694899
7744875
|
CCL26
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
10699158
16339911
22633458
|
CCL26
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15207250
12689946
22633458
|
CCL26
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
15039444
|
CCL26
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
29637711
15039444
|
CCL26
|
CX3CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
20974991
29637711
|
FASLG
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22075988
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FASLG
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22075988
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FASLG
|
FAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
17145710
8521815
9126929
1375228
1713127
14965271
21803845
9039262
11239407
25241761
9228058
15659383
12753742
7505205
12887920
15725726
|
IL4
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21115385
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL4R
|
IL13RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
IL4
|
IL4R
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21115385
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL4R
|
IL13RA1
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
CSF2
|
IL4R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
IL4R
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4R
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4
|
IL4R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
11786020
17145710
18852293
23597562
23331499
12704343
8639787
2307934
7918378
21889455
10219247
17312100
8266078
11815609
10850446
18243101
2278997
791837811786020
9874253
7721786
|
IL13RA1
|
IL4R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
12704343
16682236
18243101
8910586
|
IL4R
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
17312100
12207328
7538655
|
CSF2
|
CSF2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
CSF2RB
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
CSF2
|
CSF2RB
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
CSF2RB
|
IL3RA
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
IL3
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11700046
8649415
18692472
9278420
7957082
|
IL5
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
1833065
7957082
1495999
11748263
|
CSF2
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
1702217
2645577
18692472
8278375
2828352
7957082
|
IL2
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL15
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RB
|
IL2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RB
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2
|
IL2RB
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL15
|
IL2RB
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RB
|
IL2RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RB
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
8568232
3095922
15265897
16477002
11035066
3098894
15933202
1940342
15178252
8260650
3116143
22446627
8006584
8049354
|
IL15
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
23104097
9176231
15265897
10903799
8026467
25416956
19710453
16189514
8178155
|
JAK3
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
7693677
16189514
10825200
7973659
9553136
7973657
|
IL2RB
|
IL2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8568232
15265897
11886175
15933202
15178252
1545122
8260650
3116143
8006584
|
IFNAR2
|
IL15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IL15
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL15
|
IL15RA
|
â—¼ PROTEIN_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IFNAR2
|
IL15
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR2
|
IL15
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IL15
|
IL18R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL18RAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL12RB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL2RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL15RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17709786
17145710
23331499
15265897
7641685
10903799
19710453
8530383
16284400
|
IL12RB2
|
IL12RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10807786
11867689
12244147
12372421
14610620
15546391
19833085
20406969
21042762
21115385
22077060
24091328
24204259
27216177
7543512
8683106
8700208
9834059
|
IL12RB2
|
IL12RB1
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10807786
11867689
12244147
12372421
14610620
15546391
19833085
20406969
21042762
21115385
22077060
24091328
24204259
27216177
7543512
8683106
8700208
9834059
|
IL2
|
IL12RB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10807786
11280761
11460167
14660645
15289500
15563472
17301840
1825141
18264787
18758473
19528259
21133840
21232017
22224781
23650441
24699077
24958845
26755705
2965306
6164929
9625766
|
IL21
|
IL12RB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12244150
16081783
16785506
24751819
|
IL12A
|
IL12RB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11086056
943050
8943050
|
IL12B
|
IL12RB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11086056
8943050
1108605611940480
11940489
|
IL1B
|
IL12RB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10198225
7528775
9038232
8943050
9454765
7594594
|
IL18
|
IL18RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IL18R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IL18RAP
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IL18R1
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL13RA1
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20856220
21115385
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL4
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL18
|
CCR7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
IL18
|
IL18RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9792649
|
IL18
|
IL18R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25261253
9792649
12096920
11046021
9325300
|
IL18RAP
|
IL18R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18RAP
|
IL18R1
|
â—¼ PROTEIN_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL21
|
IL18RAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12244150
16081783
16785506
24751819
|
IFNB1
|
IFNAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
15312780
9121453
10395669
9334213
15778442
12842042
17969444
|
IFNAR2
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR2
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
IFNAR2
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR2
|
IFNAR1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
IFNAR2
|
IL15RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNA5
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10395669
|
IFNA4
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNW1
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11278538
21854986
|
IFNA2
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10395669
10339405
21854986
18027911
10984492
17001036
11888273
|
IFNA7
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA10
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNB1
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
8181059
10395669
7623815
11278538
1127853810395660
|
IFNA16
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA17
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7623815
21856167
|
IFNA8
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10395669
8969169
|
IL2
|
IL2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2
|
IL2RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2
|
IL12RB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10807786
11280761
11460167
14660645
15289500
15563472
17301840
1825141
18264787
18758473
19528259
21133840
21232017
22224781
23650441
24699077
24958845
26755705
2965306
6164929
9625766
|
REL
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17641034
7623820
22860011
11917142
11313336
7744006
17182554
9605137
21832163
8383323
8934574
21890374
8670878
21371435
15079071
9233628
27898347
8977179
8152309
11254713
8920856
16585559
7969133
8814256
7982907
12646638
9547358
24853588
|
FOXP3
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
25567984
23275607
22806628
21458306
17028180
16873067
21955384
17586580
23954131
17922010
20429413
18324310
19172156
17416586
22579476
18779564
17430097
21654845
17632414
11483607
18759924
19564342
|
IL2
|
IL2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
6815536
3095922
15265897
12649439
16477002
15933202
1940342
17032757
15178252
8260650
3116143
8894436
1993646
8580082
8960125
|
IL4
|
IL13RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20856220
21115385
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL4
|
IL13RA1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20856220
21115385
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL4
|
IL5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
CSF2RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
CSF1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4
|
CSF1R
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
FOXP3
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20554955
20573297
18395799
19775525
18374871
|
IL4
|
IL13RA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12704343
10641437
18243101
18480254
|
CXCL10
|
CXCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
18514095
18922917
22798340
23567181
|
CXCL10
|
CXCR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
18514095
18922917
22798340
23567181
|
CXCL10
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
|
CXCL10
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
9660793
12571234
10233762
9625760
15761110
12750173
10699158
9064356
16189514
12884299
|
CSF2
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
REL
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9414129
11418664
8152309
8662666
8934574
8660380
9185524
24899500
|
CSF2
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
16720384
11091218
11468284
7691413
16492764
9187659
|
CSF2
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
10753826
8910448
11777960
27396825
12393492
19833085
10572088
22323450
23331499
22869907
9211889
24030977
11306493
11867689
9187659
11015446
1702217
2645577
20406969
23046136
20805416
2828352
7957082
18551128
26192618
18692472
21765015
24091328
27216177
2555171
14610620
12811837
|
IL10RB
|
IL26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20462497
16982608
14764663
23704922
7543512
|
IL10RB
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20462497
16982608
14764663
23704922
7543512
|
IL10RB
|
IL10RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
11207245
11875494
12818165
14607900
14610620
15282297
15579430
15833879
16200688
16424049
16713974
17404308
19833085
20184663
21115385
21191065
21220452
21840487
26755705
7512720
7521688
7543512
9834059
|
IL10RB
|
IL10RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
11207245
11875494
12818165
14607900
14610620
15282297
15579430
15833879
16200688
16424049
16713974
17404308
19833085
20184663
21115385
21191065
21220452
21840487
26755705
7512720
7521688
7543512
9834059
|
IL22
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17208301
23331499
10875937
15120653
18509351
12513909
29608910
|
IFNL2
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IFNL1
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IL26
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17208301
23331499
14764663
23106140
|
IFNL3
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IL13RA1
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
31.0
|
1.0
|
ACSN
|
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20856220
21115385
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL6R
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11238858
8706672
23331499
3136546
14656210
9694899
15895091
23663276
7744875
2788034
|
CSF1
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
CSF1
|
CSF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
CSF1
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
7883784
8355686
1702217
22483114
22902366
2408759
26235028
22153499
24890514
26095744
|
IL3
|
IL3RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
IL3
|
IL3RA
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
IL3
|
CD40
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15034038
15549123
17200410
23026134
23125331
23762788
24778133
|
IL3
|
IL3RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23331499
11700046
8649415
9278420
7957082
1465408
|
IL1B
|
IL1RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9820540
7775431
20802483
|
CD4
|
HLA-DQA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
10816381
29637711
|
FOXP3
|
IL2RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12522256
17237765
17449799
21411734
|
FOXP3
|
IL17A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20221429
19877017
23409930
18434325
19088203
|
FOXP3
|
IL2RA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23144749
20554955
17028180
18606654
15466453
21036387
|
REL
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8413223
20975042
23195252
19690169
19122653
8910763
14670622
17082635
|
IL1B
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
8332913
7878046
1833184
20802483
|
CXCR4
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23109003
11406370
12495636
16189514
17169327
10506573
|
AKT1
|
GATA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
27053161
16107690
20101202
8206977
26680303
|
AKT1
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
22391560
24526064
29864144
34230470
16224021
26517694
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
IL22
|
IL10RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10875937
|
CSF3
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
10537111
10364174
15676205
16492764
|
IL21
|
IL18R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12244150
16081783
16785506
24751819
|
IFNB1
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15312780
8943354
18508557
15449939
17969444
16171819
|
IFNAR1
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNB1
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
8181059
1834641
10049744
7592797
7623815
11278538
18988627
29311663
112785381834641
|
IFNA7
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA4
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA10
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA16
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA2
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7592797
9334213
1834641
|
IFNA17
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7623815
21856167
|
IFNA8
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7592797
21856167
|
IFNW1
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1834641
11278538
|
IFNA5
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IL21
|
IL2RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12244150
16081783
16785506
24751819
|
IL21
|
IL21R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
21071413
11418623
18988627
1141862311418620
16424177
|
IL12A
|
IL12RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
11086056
7911493
11114383
12023369
8943050
7527811
|
IL12B
|
IL12RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11086056
7911493
7843232
8943050
7527811
|
IL23A
|
IL12RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23331499
11114383
12023369
12671732
18988627
|
HLA-DRA
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DRA
|
HLA-DOB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DRA
|
HLA-DMA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
IL19
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11196675
14580208
12351624
22802649
|
IL26
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20462497
16982608
14764663
23704922
7543512
|
IL24
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17208301
23331499
1297448111706020
12974481
11706020
|
IL20
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
12351624
11163236
22802649
14580208
|
IL26
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17208301
23331499
14764663
15178681
23106140
|
IL19
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17208301
1297448111564760
23331499
11564763
12974481
18988627
|
IL20
|
IL20RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
12351624
11163236
22802649
22232181
14580208
|
IL20
|
IL22RA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
11163236
|
GDF2
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17068149
25237187
|
FHL1
|
RBPJ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24952875
15710417
9418910
14999091
|
CCL13
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10477718
9790730
|
CCL3L1
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
11170631
10364178
10477718
16298345
11734558
11449371
11700073
9790730
22633458
12964882
|
CCL8
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10477718
9468473
10699158
9790730
22633458
12964882
|
CCL14
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16298345
20483925
22633458
11085751
12964882
|
CCL11
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10477718
9468473
10699158
9790730
11264152
22633458
12964882
|
CCR5
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23109003
11406370
12495636
17169327
|
HLA-DQA1
|
HLA-DMA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DPA1
|
HLA-DMA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA2
|
HLA-DMA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
JAK3
|
IL7R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15996891
20167604
7481769
27423467
10781830
22551764
|
IL7R
|
CRLF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11418668
23331499
10881176
10974032
|
REL
|
IL2RA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10221648
1508203
7636248
|
REL
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
11058167
10657616
10940886
17982049
9464836
7565674
14976188
15251981
12077291
17291992
16688168
9497375
17579043
18523276
15482860
19299558
22427889
16166378
15270850
20876114
25565375
9808189
20145200
|
REL
|
IL12A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12820969
11602633
14568984
17982049
22893703
17892401
20876114
25565375
21402701
19122653
15871905
16166378
19185846
|
REL
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15699120
20855868
24656046
22065573
8035474
22427889
|
REL
|
IL23A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17982049
23916470
20876114
18523276
19122653
19624579
19592489
17182554
|
IL34
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18467591
22483114
30205037
22729249
23478061
29796177
31616414
24890514
26095744
|
IL9
|
JAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
25297818
15143194
1376929
7718508
21439476
|
AMH
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14656470
|
BMP6
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12297674
|
BMP2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8006002
28977600
|
GDF2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
27252362
19996292
|
ACVR2A
|
GDF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
GDF2
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22622516
19996292
|
GDF5
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8702914
|
GDF7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
BMP2
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17483092
10880444
21702718
17295905
25938661
20959140
|
BMP6
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10504300
|
BMP4
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
8702914
26330344
20860622
21054789
11241215
8006002
16189514
7644468
|
IL11
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8360477
10948192
9143707
9560294
|
IL11
|
IL11RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
23331499
12740032
10948192
7670098
8940087
10504396
26551460
16189514
|
BMP2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
20385559
16446785
28977600
15064755
18988627
17295905
|
BMP2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
51.0
|
1.0
|
Omnipath
|
17145710
17483092
10880444
10712517
26330344
21054789
16672363
10881198
11263668
20860622
15064755
18937504
25938661
15621726
12700180
10692589
19804412
|
GDF1
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
GDF5
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
8702914
16446785
|
GDF2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15851468
27252362
26047946
|
GDF11
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12414726
23331499
1241472616845370
16845371
16446785
|
BMP6
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
10504300
|
ACVR2B
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
23180781
8622651
16446785
12364468
18988627
|
BMP5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11580864
16189514
|
BMP6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11401330
12297674
10504300
|
GDF6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9525338
160490149525338
16049014
|
GDF7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
GDF5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
21543859
9525338
11282024
16127465
19229295
|
GDF11
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12414726
|
CTF1
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
9030543
11834704
|
CLCF1
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10966616
9143707
|
IL5
|
IL5RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
23331499
1833065
7721873
10823900
1732409
10880230
22528658
7957082
1495999
8567620
11748263
22153509
|
IFNL2
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IFNL1
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IFNL3
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IL17A
|
IL17RC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16397230
16785495
8777726
11574464
|
IL17A
|
IL17RC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17911633
19838198
18684971
|
CCL11
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9660793
96607939660793
22633458
|
CCL11
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
15207250
9276730
9115216
9195948
11264152
22633458
12554737
12149192
|
CCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
10488147
10699158
22633458
12218106
23597562
25450766
12149192
16102831
8642344
9169459
9005985
16339911
8676064
9276730
9207005
24702154
9712872
10733106
10706854
12761559
8609214
10854442
|
EDA
|
EDA2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11039935
10484778
12270937
12084975
|
HLA-DQA1
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA1
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA1
|
HLA-DOB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA2
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA2
|
HLA-DOB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA2
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
GH2
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
2387255
1955498
|
GH1
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
2825030
8943276
17500058
1549776
9353194
26713839
1935820
31279174
9030599
23331499
7862673
7691587
19927328
10551877
21889455
9571026
3349036
2387255
31100495
29145629
24280222
24243840
|
EDA
|
EDAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
11039935
18304980
10484778
11309369
11035039
12084975
|
EPO
|
EPOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
17145710
8662939
9442088
15358619
9030560
9974393
9774108
18586265
23331499
2163696
10318834
21889455
17327410
16982323
29997244
9808045
|
GATA1
|
EPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16471262
8677751
8288642
|
IL1RN
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20959797
24332029
1834644
7878046
1833184
|
IL12A
|
IL12B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
10779781
10899108
8943050
7527811
|
IL12B
|
IL23R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12023369
17587057
|
IL23A
|
IL23R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
1202336912023360
12023369
|
IL22
|
IL22RA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
12941475
10875937
29608910
15120653
5898511035029
20462497
18675809
12513909
18599299
11035029
|
IL17RC
|
IL17F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16397230
16785495
8777726
11574464
|
IL17F
|
IL17RC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19838198
18684971
17911633
28827714
|
HLA-DOB
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DOA
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DPA1
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
IL20RB
|
IL19
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11196675
14580208
12351624
22802649
|
IL24
|
IL20RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
11706020
|
IL19
|
IL20RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
22802649
14580208
|
CCL8
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10699158
22633458
9115216
|
CCL23
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9886417
9558365
12381680
10699158
10660125
22633458
|
CCL3L1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11170631
11449371
12381680
9115216
9624164
7545673
10202040
10660125
22633458
8530354
|
CCL14
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9687537
9548457
15905581
12381680
20483925
9346309
9405404
24218476
22633458
11085751
|
CCL8
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10699158
9005985
|
CCL28
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
22633458
12964882
|
CXCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
15178708
|
CCL3L1
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11449371
7594543
22633458
|
CCL13
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9276730
10733106
9005985
10699158
16339911
22633458
12149192
|
CCL14
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9548457
9346309
11085751
|
CCL24
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
22633458
10733106
10699158
16339911
12218106
|
CCL18
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
10640766
29637711
23999500
24218476
22633458
23951310
|
CCL20
|
CCR6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10498628
9223454
10488147
9169459
9294137
10699158
12081481
24218476
22633458
12964882
|
CCL20
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9660793
|
CLCF1
|
CNTFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11294841
11285233
10966616
|
CCL13
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CXCL13
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11554781
16189514
22633458
|
CXCL11
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
15273303
9625760
15761110
12750173
10699158
16189514
11259614
12884299
|
AMH
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8889695
23331499
8119126
16446785
18988627
79972308889695
7997230
|
CCL8
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9115216
10699158
9195948
22633458
12554737
12149192
|
CCL24
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15207250
|
CCL13
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9276730
10699158
24890717
9195948
22633458
12554737
12149192
|
CCL27
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10781587
11821900
12718728
10725697
22633458
|
CCL28
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
10781587
22633458
|
CXCL13
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
CCL25
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
GDF1
|
ACVR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
EBI3
|
IL27RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12121660
|
CX3CL1
|
CX3CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9390561
10488147
14607932
10699158
28389721
11432858
16189514
22633458
9931005
|
CXCL13
|
CXCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
22913878
9486651
9463416
10699158
28389721
22633458
|
IL17B
|
IL17RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10749887
24011563
11058597
1074988710749880
|
IL25
|
IL17RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
24011563
11058597
19838198
1105859711058590
|
CCL17
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12832759
10699158
9521068
10910894
|
CCL8
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
26740381
9405404
10734104
|
CCL13
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
26740381
16189514
9405404
10734104
|
CCL25
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10706668
23341447
22633458
|
IL24
|
IL22RA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
|
CCL1
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
12967681
16221874
9207005
12645948
9211859
11470772
10699158
11154210
9469461
10419462
10910894
|
IL31
|
IL31RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
15184896
15194700
|
CCL25
|
CCR9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10498628
10699158
11159507
22633458
10229797
|
CCL18
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24218476
23999500
|