Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
JUNB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12791272
ATF2 JUND â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MK08 PAXI â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 30120307 23397142 12853963
MK08 HSF1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10747973 27043084
IRS1 RPTOR â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 30240640 19561084 16354680
LAMP3 MK08 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MK08 RPTOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22493283 27043084
JUN P53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 31182485
MYC ELP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
LAMP3 MP2K7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYC TKT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
JUN JUND â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649
MK08 ATE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
M3K7 MK08 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17709393 11865055
MK08 CBL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16982329 11944898
MK08 KCAB3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DUS1 MK09 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8626452 28675297 11359773
MK08 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7642542 16982329 25284480
MK08 TKT â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
MK09 JUNB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 8654373 8945519
MK08 H2AX â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17145805 20512932 19234442
MK08 JUNB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9889198 9405416 8917518
ELK1 MK08 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8654373 8846788 17875713 8586671
MK09 WDR62 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19910486 21749326 25416956 32707033 16189514
DUS4 MK09 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32296183 8626452 25241761 28675297
M3K7 MP2K4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12556533 12429732
M3K1 MP2K7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 14500727 15866172 17110930
MK08 DUS1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11278799 28675297
MK08 KS6B1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21988832 23816567 11279232
ATF2 JUNB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
JUND ATF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20102225
DUS22 MK08 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12138158 11346645
MK08 DUS8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27880917 21900206 26186194 27432908 28514442
MP2K4 MK09 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12788955 21900206 11062067 22366412
EGFR MK09 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
JUNB JUND â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
CRK P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 10962563 12878163 11418612 25814554 19380743
DUS16 MK08 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32296183 27432908 28675297 11489891
WWOX MK08 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12514174 18371080 15580310
MK09 ATF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12788955 7737129 602896 32296183 12110590 11865055 8654373 16533805 25416956 17875713
MK09 P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 12384512 22366412 16713569 9393873
MK09 DUS8 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27432908 23602568 32707033 27880917
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MK08 JUND â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22327296 16264271 12052834
ELP1 MK08 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12058026 16713569
MK08 WDR62 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 19910486 26186194 28514442 32707033
DUS10 MK08 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10597297 32296183 28675297 10391943 16166642
DUS4 MK08 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16038800 19843478 28675297 11387337
MK09 MK08 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 25284480 28514442 23602568
EGFR MK08 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
MYC P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28205554 28628118
JIP3 MP2K7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32427938 10629060 12189133
JIP1 JIP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 16456539 10629060 33961781
JIP1 M3K7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18286207 17709393 16840345
JUNB ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 16511568 20102225
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
CBL P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9918857 19190244 17237826 7544353 10358153 8662998 9259313 8621719 14530346 15581361 7642581 15556646 9890943 16219545 10918571 8995243 16135792 9414268 8702998 8612729 19861161 16713569 11157475 19380743 11042121 16289966 9234717 16982329 8896416 9178909 33512474 8941725 11944898 25814554 9541596 9890970 9461587 9160881 7791764 9174058 8695807 24113870 11133830 11087752 18374639 9092538 10025673 9988765 11418612 15107835 21203488 11994282 10620516 11030146
P85A EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 21701776 7531698 31959764 22973453 8662998 25241761 16230374 7797556 25754235 25187647 16713569 7499252 16273093
MK08 GSTP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16636664 25241761 11279197 26429914 12646564
MK08 CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25241761 11432831 16982329 16713569
MK08 IRS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10722755 11606564 12417588 12351658
MK08 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9732264 11108663 19651615 12514174 15580310 16713569 18813780 9724739 9393873 11283254 15538975
M3K1 MK08 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15299005 9405400 21152872 25241761 14500727 12228228
MK08 MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 1748630 16713569 10551811
DUS10 MK09 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27880917 32296183 28675297 11359773
DUS16 MK09 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27880917 32296183 27432908 11359773 28675297 32707033
MK09 JIP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9733513 10490659 15998799 28514442
WWOX P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16219768 31315632 14965474 12514174 15580310 16713569 11058590
RPTOR KS6B1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12150926 23184942 21795849 25273559 33852892 21071439 16183647 26348909 15809305 12604610 16837165 22493283 19402821 17386266
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
IRS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10854852 19546233
EGFR CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10595738 9480911 9642287 24658140 31980649 11956190 16729043 22973453 8875975 25402006 9617486 16273093 12198159
JUNB EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10803405 23455325
MYC ELK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC GSTP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TKT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8788173 9212167 18414489
JIP3 MP2K4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 12189133 10523642
JUN JUNB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 25609649 28514442 33961781
JIP3 MK09 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10629060 11024282 12189133 10523642 32427938
MP2K4 MK08 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12788955 9162092 10713157 12391307 16533805 15998799 11279118 11707464 9661668 32707033 13130464 11062067 9808624
JIP3 MK08 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 16141199 10629060 12189133 10523642
MK08 JIP1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 9733513 16840345 16343492 18286207 16533805 15998799 28514442 12756254 11700324
MK09 JUN â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19910486 17189706 9596579 8985011 16824735 19527717 16533805 8001819 17875713 10490605 9405416 18940813 1922387 11278395 12788955 17637567 15637069 8654373 8945519
PAXI CRK â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10085298 16713569 26656091 12799422 12198159
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
MK08 ATF2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7737129 9399639 9162092 11566021 15550563 9405416 12958075 12874243 11865055 7535770 8654373 7737130 12804775 9207092 16533805 21444723 11279118 17875713
MP2K7 MK08 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10713157 25241761 24975362 12821118 16533805 9207092 25284480 26364603 13130464 11062067
JIP1 MP2K7 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 18286207 16456539 10490659 16840345
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
P85A IRS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 8382612 8175658 7680095 17640984 23643389 16230374 26839216 7659087 9564850 14511371 12220227 7486683 1381348 15514089 22974441 12730242 16043515 16150444 16354680 16880210 12107746 30240640 33991522 19561084 8628286 14632132 25814554 7935461 7680644 8388384 29526746 11416002 1334490 23439647 12173038 25273559 11403293
MK08 JUN â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 16142216 15677475 14517282 15958389 16007099 16983342 8846788 16824735 9990010 17875713 11479302 10747973 9032244 18957422 12228228 11278395 15590691 25098452 10419510 10908726 11108663 7527398 18429822 22327296 23816567 19527717 16713569 15894542 14633987 15299005 16549498 18003900 10393177 12697749 19910486 8224842 8137421 11907583 8586671 17363973 22110360 20514406 12963725 16157600 16291755 14701799 9774977 10987838 8621542 11532856 12149229 9692890 16166642 15302935 16740711 16434970 17189706 15289320 10398438 19270716 22904686 18922473 10962563 10585392 15749833 12052834 16533805 8001819 12407442 10101227 20732415 12185592 10464310 9207092 14557262 14612408 20133937 8654373 9575168 14572659 15143066 12832416 13130464 9808624
M3K1 MP2K4 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10713157 15299005 14500727 12228228 27806347 16472679 14581471 15866172 9808624
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
IRS1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9837978 8810325 8621590
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
EGFR GSTP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19254954 26429914
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MYC JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 2123531 7775604 12695333 18838534 18414489
RPTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025