Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBE2I NMI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HGS NMI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
H4C6 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
PARP1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
UQCRFS1P1 DTX3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AR PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 20610535
AR NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22347519 23145211
NOTCH1 DTX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14567914 15965470
ITCH DTX1 â—¼   COLOCALIZATION 2.0 0.8 intact 17028573 5219205
UBE2K DTX3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPIB DTX3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HGS UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
IFIT3 IFIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NOTCH1 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8313469 19567869
NOTCH1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330899 22363130
PARP14 PARP9 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DTX3L PARP14 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HIST1H2AB HIST1H4A â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIST1H2BJ HIST1H4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST1H2AB HIST1H2BJ â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
DTX3L PARP9 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DTX1 NOTCH1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
NMI STAT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9989503 16189514
RNF111 UBE2D2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
H2AFV HIST1H4A â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
DTX3L UB2D3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19549727 12670957
ITCH UBE2D3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IFNGR1 STAT1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
JAK2 STAT1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DTX3L UB2D2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19549727 12670957 19818714
DTX3L UB2D1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19549727 12670957 19818714
DTX3L PARP9 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
STAT1 NMI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
DTX3L H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19818714
NOTCH1 DTX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10933396 9881968 15356142
ITCH DTX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17028573
STAT1 IFI35 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
STAT1 JAK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12223098 21239533
ITCH UBE2D2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
IFIT1 IFIT3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
IFI35 NMI â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
ITCH DTX1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 18628966 17028573
UBE2I UBE2K â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
IFIT1 IFIT3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HGS STAM â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NMI STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9989503 16189514 17085014
AR UBE2D3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
DTX1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11153911 20208568 23331499 21071413 11226752 11564735 22162134 18988627
STAT1 IFIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21056555 17050680 17933493
JAK2 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK2 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNGR1 STAT1 â—¼   ENZYMATIC_REACTION ✅ 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12133952 8232552 8550631 8156998 7796299 7615558 8649432 19041276
IFNGR1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10848598 23285134 28143527 24608040 24366643 7514165 27378243 8156998 8605876 8662591 15780933 8910398 28445952 24443556 24777831 26113305 22162832 15494521 7615558
IFNGR1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11438544 15864272 17063185 23898330 12040185 7499845
ITCH NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12682059 10940313 23331499 16713569
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 STAT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
JAK1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 132.0 1.0 Omnipath 35317858 11839738 10918587 15261459 34950606 11306517 8756628 12244150 8156998 9535918 10748192 7657660 12817007 23257612 27774606 25297818 22306691 8631301 7510216 14963018 15284024 24243840 7592750 10851062 11823427 23331499 7532278 11418623 11722592 18988627 12637327 27387064 8662591 10022928 19088846 32953130 7796299 7504784 23124025 19787091 24058793 20169197 7543024 15322115 18941194 19534553 15978943 14978237 11294897 14764663 21429244 14565860 34228987 25386349 18989459 34521819 9020188 19535621 10982844 21576360 12759422 18508557 8232552 12093291 12040185 20006573 8662795 7690989 20087684 11438544 20035788 11972023 29145629 9355737 11152457 12517932 18389480
JAK2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
JAK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 11839738 10918587 7888666 20353823 7543024 15322115 25950470 23331499 21071413 14978237 11294897 7690989 7504785 18988627 12637327 25535282 11438544 21576360 10748192 7657660 12817007 14984365 7504784 21207025 9355737 11152457 7615558 19834108 15284024 10982844 7592750 19787091
JAK2 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 9133424
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368