Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MITF GPR143 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19067971 1999537
LEF1 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10747853 12048204
PITX2 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728254
LEF1 PITX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728254
PRKCB MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917261 9891069
MITF PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16411896
NEUROD1 TYRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9447965 14632202
SOX10 TYR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17516925
ATM CREB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15073328 17209043 16293623
TFE3 MITF â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 11818452 11930005
MITF LEF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12032083 12048204
PAX6 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350962 16189514 12756174
PAX3 SOX10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10942418 11029584 12668617
SOX10 TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17516925 16757562 21210960
TBPL1 TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7510966 12663655 8995290
NEUROD1 TCF4 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
PAX6 MITF â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 16189514 11350962
ATM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16293623 15073328 17525332 15212693 23642045 19115993
ATM HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24821553 11980910
CREB1 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19937254 10841026 17083486 22496449 19067970 18039926 21519923 16327152 24267286
LEF1 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12032083 12048204
MAPK8 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9030579
SOX10 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10973953 10982026 15760336 10938265 16494873 19026785 10942418 16921166
POU3F2 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18829533 22290434 18628967 24062982
PAX3 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10982026 22290434 10480898 19074888 19403660 9500554 19026785 20925909 11237412 10942418 10644012 21965087 21519923 11830592
MITF TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 1999537 12093801 18424413 8995290 23098757 20099279 8707852 17516925 22259223 12136092 12034359 17083486 8645245 20482673 12204775 21519923 15558216 19067971 9170159 12663655 10080955 9647758 14717844 10587587 23876066 9158138 11532965 8749302 20485200 9500554 7969144 23872139 24769727 21910056
MITF PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9466887 23610061 17277739 15978250
MITF TYRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11310793 1999537 22371403 8995290 19067971 8749302 10080955 17457519 12204775 11237412 19995375 12136092
SOX10 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10973953 10982026 10942418 10938265
PRKCB TYR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10347209
TBPL1 TYRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8995290 3026921 1142425 6337120 1756720 793630 1268252 796672
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368