Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MITF BRAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23831555 16001072
TBP EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9699517 8152794
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
POU3F2 GNRH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15561800
TTF1 GNRH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11036938 11161473
POU3F1 GNRH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9032292
POU3F2 GNRH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11875100
NFYC NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857858 22969033
USF1 NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21770893 12697323
POU3F4 POU3F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9105675
RB1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11094070 16713569
SOX10 TYR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17516925
EGFR SGPL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 23956138
NFYB EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9799238 15454570 10075648
BRAF MAPK1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
TBP NFYB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9153318 16713569
BRAF MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
POU3F1 EGR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11782409 19922439 16311519
SOX10 EGR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22492709 19922439 12538520
SOX10 EGR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16582099 16311519
NFYA HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
MAPK1 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19237534
POU3F2 NES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18923447 19147497 18349072
NFYB NFYA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14681455 15243141 15831478 32296183 26344197 12857729 26496610 17098936 23332751 16959611 8051128 25416956
PAX3 SOX10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10942418 11029584 12668617
TBP RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9242374 10197586 9400991
SOX10 TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17516925 16757562 21210960
NFYC NFYA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 33961781 35140242 15243141 32296183 26344197 12857729 23332751 20936779 26186194 28514442
NFYC NFYB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 35140242 32296183 26344197 26496610 12401788 20936779 21988832 28514442 9388234
GTF2B TBP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NFYA NFYC â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYA NFYB â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAPK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 14654779 21478863 19541618 16508002 19710016 19933846 15664191 29335436 8621729
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
EGR2 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16136673 25974668 11734543 8842374
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660747
TBP GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7666533 8670811 11971135 8946917 9121468 9407004 7706261 16330756 7823952 7609077 8051080 8087622
MAPK1 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 21887372 10952390 16162175 29121864 9440696 10673502 12819038 20701798 27428965 16246839
SOX10 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10973953 10982026 15760336 10938265 16494873 19026785 10942418 16921166
POU3F2 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18829533 22290434 18628967 24062982
PAX3 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10982026 22290434 10480898 19074888 19403660 9500554 19026785 20925909 11237412 10942418 10644012 21965087 21519923 11830592
MITF TYR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 1999537 12093801 18424413 8995290 23098757 20099279 8707852 17516925 22259223 12136092 12034359 17083486 8645245 20482673 12204775 21519923 15558216 19067971 9170159 12663655 10080955 9647758 14717844 10587587 23876066 9158138 11532965 8749302 20485200 9500554 7969144 23872139 24769727 21910056
SOX10 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10973953 10982026 10942418 10938265
POU3F2 POU3F1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19922439 21423190 21423191 22814607 16311519 18803322
SOX10 POU3F1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19922439 21423190 21423191 22814607 16311519 18803322
YAP1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457