TBK1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TNFAIP3
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11389905
5214127
|
SPRED1
|
FAM161A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SPRED1
|
LMNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SPRED1
|
TNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
IL10
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12773629
|
HTT
|
CRYAA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TNIP3
|
CRYAA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
KPNA3
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
UBC
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
NFKB1
|
TNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18081698
|
BMI1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6948569
19233177
|
UBC
|
TNFAIP3
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
NF2
|
TNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HNRNPC
|
TNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
NES
|
TNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TNIP3
|
TRIM63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
31391242
233395
|
TNIP3
|
TRIM55
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
31391242
233395
|
TNIP3
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TNIP3
|
LMNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TNIP3
|
KLK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DAZAP2
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBC
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18636086
6804508
|
FAM161A
|
LMNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TRIM8
|
TNIP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
32268115
|
BMI1
|
LMNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26468281
34316702
|
TNAP3
|
TNIP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25416956
17088249
32599618
|
TNAP3
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30561431
19615732
15661910
21885437
|
TAX1BP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
TNIP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
TNF
|
TNFAIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
IKBKG
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
YWHAB
|
YWHAH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
IKBKG
|
TNFAIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
TNFAIP3
|
TNIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
TAX1BP1
|
TNFAIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
TNIP1
|
TNAP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
25416956
16713569
10385526
21988832
18029035
12586352
25165885
11389905
12965196
30561431
|
IKBKG
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
NFKB1
|
TNIP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14743216
21988832
19695220
35140242
33961781
25609649
|
NFKB1
|
TNFAIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11880364
19343319
10807933
|
TNFAIP3
|
TBK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18353649
15661910
|
NF2
|
LATS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26045165
24012335
|
TNIP1
|
TNFAIP3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
5214127
11389905
|
IL10
|
KRTAP10-8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
IKBKG
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
LATS2
|
NF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
TNFAIP3
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
IKBKG
|
TNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
38.0
|
1.0
|
ACSN
|
10542212
10754326
10952726
11875494
12133805
12907458
14660645
15199157
15465827
15485931
15536066
15644117
15749903
16243976
16413922
16818229
16878026
16970925
17237376
17254973
17363905
17404308
17485448
17693255
18716620
20138012
20300203
21217011
21807870
22435554
23086447
23390297
23422957
23430059
2649237
28462531
7594497
9743347
|
IKBKG
|
TNIP3
|
â—¼ SHARES_COMPLEX
|
|
|
38.0
|
1.0
|
ACSN
|
10542212
10754326
10952726
11875494
12133805
12907458
14660645
15199157
15465827
15485931
15536066
15644117
15749903
16243976
16413922
16818229
16878026
16970925
17237376
17254973
17363905
17404308
17485448
17693255
18716620
20138012
20300203
21217011
21807870
22435554
23086447
23390297
23422957
23430059
2649237
28462531
7594497
9743347
|
NFKB1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
MAP3K7
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
TNF
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
TNF
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
IKBKG
|
IL6
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
38.0
|
1.0
|
ACSN
|
10542212
10754326
10952726
11875494
12133805
12907458
14660645
15199157
15465827
15485931
15536066
15644117
15749903
16243976
16413922
16818229
16878026
16970925
17237376
17254973
17363905
17404308
17485448
17693255
18716620
20138012
20300203
21217011
21807870
22435554
23086447
23390297
23422957
23430059
2649237
28462531
7594497
9743347
|
NFKB1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
MAP3K7
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
24911653
11477091
17301840
18180283
19909372
15125833
24699077
17363905
16356855
18641653
24403530
18079694
18223652
14514672
17496917
19531477
20300203
11325957
21133840
21232017
18264787
9744859
10391247
16799562
15836773
10702308
23109003
12620219
14633987
17363973
19161412
22941947
23681101
17047224
29145629
11280761
16301747
15082531
26192618
14660645
20038579
24958845
15327770
20164171
11460167
16603398
21041997
|
TNFAIP3
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
21988832
11389905
22099304
23032186
20932475
26802121
31585000
10755617
|
TNIP1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21988832
16684768
18212736
20010814
|
IKBKG
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
TNF
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
IL6
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
TNIP3
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
38.0
|
1.0
|
ACSN
|
10542212
10754326
10952726
11875494
12133805
12907458
14660645
15199157
15465827
15485931
15536066
15644117
15749903
16243976
16413922
16818229
16878026
16970925
17237376
17254973
17363905
17404308
17485448
17693255
18716620
20138012
20300203
21217011
21807870
22435554
23086447
23390297
23422957
23430059
2649237
28462531
7594497
9743347
|
LITAF
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22138218
12177065
11708771
10200294
16804395
16872372
17283168
12655064
21980379
|
NFKB1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17513725
12058956
24337575
12657243
17704137
12471036
17707233
7624137
11259437
12686724
16433741
26114754
20237317
7876168
16707469
12117498
14976218
10485496
15465827
8622636
15812247
21138578
18990758
10748079
15013838
15749903
16916598
17646159
10754326
16040075
10837498
18285351
11675405
11739517
15743782
20066113
20617556
17085785
8530146
8805669
10919279
14960579
1740105
10963848
16055086
9742085
17292554
10553096
11312646
15543947
17442180
16285952
10079106
11297551
10551799
10201927
12907458
8679226
9281604
22782967
8219230
11749970
9916895
11094063
11490006
7895918
1618817
16483936
18057724
20722069
16569682
9452482
17407192
17082635
|
IL10
|
TNIP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
10925299
11207245
11438547
11875494
12193690
12811837
12818165
14607900
15282297
15579430
15749903
15833879
16200688
16424049
16713974
17404308
17485448
20184663
20435894
20547845
21115385
21191065
21220452
23124025
23508573
24378531
26755705
9834059
|
NFKB1
|
IL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15465827
9310124
19124729
19766270
16835236
|
TNIP3
|
IL6
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
38.0
|
1.0
|
ACSN
|
10542212
10754326
10952726
11875494
12133805
12907458
14660645
15199157
15465827
15485931
15536066
15644117
15749903
16243976
16413922
16818229
16878026
16970925
17237376
17254973
17363905
17404308
17485448
17693255
18716620
20138012
20300203
21217011
21807870
22435554
23086447
23390297
23422957
23430059
2649237
28462531
7594497
9743347
|
NFKB1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
71.0
|
1.0
|
Omnipath
|
17513725
18061164
12058956
24337575
19124729
15611045
11058167
9523851
15517885
12887736
15158360
7876168
17495236
25549935
17982049
15241416
18243142
9516466
2405250
18996370
8824277
18310089
24664372
15749903
10903137
16112536
14532843
11327783
18942706
11975924
20066113
16984731
10975857
11160296
19703987
22895549
10963848
10469356
22547075
17040605
11459775
17490702
19469019
8247545
11504280
15756023
10569191
10823821
20696864
12907458
19707556
16043358
11035101
12176740
11302724
8679226
8725624
22578249
8752656
17196927
17532054
12727841
18057724
7499267
10329846
9199307
9502421
19164127
11120852
24676671
11098847
|
NFKB1
|
TNFAIP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
1332946
21725609
23178297
23572150
|
TNIP1
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
21988832
25609649
14743216
19695220
|
TAX1BP1
|
TNFAIP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18246070
34454289
20599425
23018911
32296183
10435631
18239685
11389905
|