Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP THY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCR8 THY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ETS1 LCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7970721
HTR6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7214551 17189269
SNCA FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN HTR6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7214551 17189269
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
HTR6 THY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ID2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
POU5F1 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17068183
LCK SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11078745 12096713
STAT6 THY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17312100
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
THY1 LCK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 1351058 16189514
THY1 FYN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 1351058 16189514 16713569
ETS1 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16564026 24058639 11278621
FYN ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18541700 23144976 11536198
NHEJ1 NSA2 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12893833 11162638 11744621 28671665 17570479 16713569 24860424 11078745 12096713
NHEJ1 THY1 â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368