Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
HTT AP3B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK3 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
BMX TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217965 16186805
TP53 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20160719 20074560
CSNK2A1 CCAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24962073
COPB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
USP24 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23159851
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 DYNC1H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9781666 9627114
HIF1AN EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12573436
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
ETF1 RPS11 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
USP24 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT RPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC JUNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
UBC TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
XPO1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17268548 17891139
JUNB EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21937452 15308641 17510411
GCN1L1 NAA25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
LYPD3 ECM29 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
LRRK2 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 AP3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24725412 27424887
XPO1 CNOT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 26673895
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NHEJ1 USP24 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ETF1 RPS2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RPS11 RPS3 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
TP53 XPO1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RPS2 RPS3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
ABCE1 RPS3 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
RPS11 RPS2 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
COPA COPB1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
ABCE1 RPS11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
COPB1 COPB2 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
ABCE1 RPS2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
COPB2 COPA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9482852 14729954 10921873 26344197 22939629 8940050 8537409 22863883 9751720
COPA COPB2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPS11 RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
IARS RARS â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPB1 COPB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS2 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPA COPB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CNOT1 CNOT2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAPK3 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
LRRK2 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
CSNK2A1 EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11500362 18669648
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
PRKAA1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11020388 21940946 12379484 15006641 12590608
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
GDI2 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
MAPK3 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20041225 15950189 21738525
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
NHEJ1 NCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.3 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368