Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CNTNAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 CDH15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 PAX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11753601 9916993
H3-4 APAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EIF2AK3 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16595687
ATF2 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17189429 17700520
ATF2 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11413310 12388374
ATF2 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17700520
SP1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15837784 11466608
E2F3 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18469863 12527885
E2F3 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12527885 18319725
CHEK1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0706013104 17686975
H4C6 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
ATR H3-4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
ATR SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18619531
PAX3 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10871843
CASP9 BIRC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11024045 5213055
FOXP3 CASP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23201402 20554955
CDC27 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0913813107 20439707
CDH1 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0913813107 20439707
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
EGR2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16708405 18779345
E2F3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10030670 18319725
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
AKT1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
FLT3 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28522571
CEBPG FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11473033 8567694
ESR1 CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18563714
ESR1 CXCL12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16912174
GADD45A DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DYNC1I1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
EIF2AK3 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029953
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
TP63 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9405685 9032395
CEBPB GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16418324 11012671
TP63 CASP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23703390 16103071
TP63 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22777354 23837456
TP63 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17632082 19719829
TP63 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15944736
YBX1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17893273 18800033
CREB1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
ETS1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22869003 20428211
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
CALM3 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
CALM1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
SP1 CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9348238 10945244
CALM1 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
CALM2 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
ATP6V1G1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESR1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12603855 26790618
SP1 CCL5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19124744
ESR1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 19039095
HES1 FLT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25234168
EEF1A1 FAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ETS1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11970950
CEBPB FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7543095 11473033
EIF2B3 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16288713 15054402
EIF2B2 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887689 15054402
GNAO1 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ETS2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12658630 18319327
GATA3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20189993
CDH1 ANAPC11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9734353
CD4 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CREB1 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9765424
HLA-DQB1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11535811
CREB1 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24298014 17591856
FOXP3 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23201402 20554955
SP1 ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20045441 12560478
ETS2 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9334186 16189514
ESR2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138116 16423895
SP1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12706891 8247540
SP1 PAX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 18314536
SP1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7779811
SP1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15486968
SP1 H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7880446
SP1 CXADR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22190856
SP1 ENTPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18812468
ETS1 CDH5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10828886 17563748
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
ACP5 EGR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H2AC4 HLA-B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CREB1 HLA-DQB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1324879
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CREB1 AICDA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
CEBPB CDH3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20385540 23405208
EEF1A1 H2AC12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EEF1A1 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
ESR1 AICDA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23181348 19139166
ANAPC7 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
CDC27 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
CFB CFH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1067618 301546
CDC16 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC7 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 10500174
CDC16 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 10500174
H3-4 DYNC1I1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 DMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CAMK2D CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20668654 1000426
CNTNAP1 CNTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11069942 9118959
HLA-DQA2 CD3G â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
EPOR EPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
GATA3 EPOR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23577103
CFD CFB â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 809512 279011
CD55 C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
CFI C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
H3-4 H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC5 H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H2AC20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC14 H2AC14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC14 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC14 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H3-4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC21 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC12 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 H2AC14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H2AC21 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H2BC5 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC12 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 HLA-DOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC5 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EP300 ETS2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14722092 10942770 10358095 15572696
EP300 ATF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10327051 24069158
ESR1 FAS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
CAV3 CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GPS2 CREB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ATM CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 20068082
FPR2 GNAI1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
BCL2L1 APAF1 â—¼   PHYSICAL_INTERACTION ✅ - 0.82 0.82 Signor 9539746
EIF2S1 EIF4G1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
HLA-DQA2 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATR ABL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10608806 20798688
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
CCNA2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PAX3 DAXX â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11244500 10393185
CDC27 BUB3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27114510 22193957 33961781 32152539 32076268 21926987
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
EIF2B5 EIF2S1 â—¼   GTPASE_REACTION ✅ + 0.83 0.83 Signor 15054402
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CD74 CTSL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CALM1 FAS â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EIF2B3 EIF2S1 â—¼   GTPASE_REACTION ✅ + 0.83 0.83 Signor 15054402
CALM3 ESR1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CALM2 ESR1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
C1QC C1QB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21054788 16189514 12960167 28325905
CEBPB SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16651265 12847250 12665574
AKT1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 0.84 0.84 Signor 18423396
APAF1 BCL2L1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CALM1 CAMK2D â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 CAMK2B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CALM3 FAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CDC27 CDH1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ATM CREB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16293623 17209043 15073328
CASP10 FAS â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
ETS2 ETS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 9334186
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
CDK6 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 16160006
CALM1 ESR1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
AKT1 FAS â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25640309 31980649
CREBBP ETS1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
CAV3 DAG1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10988290
ATP6AP1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CDKN1A GADD45A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
DAG1 CAV1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 11724572
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
CDK6 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 16508017
CFH CFI â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ANAPC4 BUB3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ABL1 ATM â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
AKT1 CDKN1B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CEBPG ATF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23661758 33961781 12805554 20102225
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
CEBPB CEBPG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12177065 20102225
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
CDK4 CDK6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 28205554 28628118 33961781
ESR1 GATA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
EIF2B4 EIF2S1 â—¼   GTPASE_REACTION ✅ + 0.88 0.88 Signor 15054402
ATP6V1B1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EIF2AK1 EIF2S1 â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 10563826
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DYNC1I1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DYNC1H1 DYNC1I1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ABL1 ABL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15735735 12569093 27229929
CDKN1B CCND1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 34591612
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
ATP6V1E2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DAXX ETS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15247905 16861237 10698492
ANAPC15 ANAPC16 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EEF1A1 EEF1A2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDK6 CDKN1B â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BIRC3 CASP9 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
ATM ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9168116 17409407 10212258 20798688 11375976 9168117
ABL1 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19783996
ABL1 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20798688
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
ATF2 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9511728 10777595 7843287
ATF2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23800081 10506225
ATM AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15546863 15899889
CHEK1 ATR â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15190204 10859164 11390642
ETS2 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19411629 19179380 10082528
CREB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11450946 16205321 18830594
CEBPB BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19043455
BIRC7 CASP9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 25416956 11024045 11084335 11801603
CASP9 BIRC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16701639 25241761 21988832 16339151 9545235 15069192
CCND1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16061635 9039267 11073968
CEBPB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22242598 11162569 12810706
ETS1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19499154 15579511
HLA-DQA2 CD74 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
SP1 CD74 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8955189 10567217 17511886
EEF1A1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A DYNC1I1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CEBPG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10982390 9442037 15041706
ETS1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18955504 12740370
CREB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25379405 14520699 21295542
HES1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19541765 19321451 11809764
ESR2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19487281 14729654 23907131
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
CEBPG ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9192779 8756629 12949251
CHEK1 E2F3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19917728
EP300 CEBPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28428115 9343424 14630807 12471036
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
GADD45A EEF1A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
SP1 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12840223 11297539
CALM3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
CALM1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
CALM2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
C1QC C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QC C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QB C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QB C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
GATA3 CD40LG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18719603
CD2 CD58 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 19398758 19494291 26794910
CD2 CD58 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 19398758 19494291 26794910
CD2 CD4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
CREB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17471497 24038085 22031759
PAX3 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18308300 20833714 21169561
EIF2B4 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16288713 8887689 15054402
CD58 CD4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
ETS1 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19917777 8356078 9780181
GATA3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21965331 21131965 18162042
CAV1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11563984 23634843 22230296 19595769
ESR1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12138116 18414489
SP1 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14741200 22138754
SP1 CDH3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19882246 9328434
SP1 CD9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8760289
SP1 DMD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27143785 15550398 19943855
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
ABL2 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19563810
HLA-DQA2 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19515975 23108396 20023423
ESR1 CCL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 CD24 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18404683
CDC16 CDC27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24100295 20360068 17187060 21186364 26496610 22193957 9356466 20733055 21043528 27114510 7736578 16648845 25306918 12956947 9628895 32076268 22939629 10922056 16364912 33961781 27173435 32152539 9405394 14657031 26344197
ANAPC4 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25383541 10500174
ANAPC5 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
CDC27 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25383541 10500174
CDC27 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
CFH CFI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26806831 9291131 1401896
DMD DAG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19109891 10932245 10355629 7592992
EPOR EPO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9030560 29997244 9808045 17327410 9774108 26481148 15358619 10318834 8662939
GATA3 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8677751
CDK6 CDKN1A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DYNC1I2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
EPO EPOR â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
C1QB C1QC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
CALM3 CAMK2B â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CALM2 CAMK2B â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ATR CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 15775976
ATP6V1B1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCNA2 CDKN1A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DAG1 DMD â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ATP6AP1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1C1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1F â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1F â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
DYNC1H1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ATP6V0C ATP6V0D2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATP6V1C2 ATP6V1F â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CDKN1B CDK4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5219242 17053782
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ATP6V1C2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC15 CDC27 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC15 CDC16 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC15 ANAPC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ANAPC15 ANAPC7 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ATP6V1B1 ATP6V1E2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ATP6V1B1 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ATP6V1C2 ATP6V1E2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V1B2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATP6V1C2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATP6V0C ATP6V1E1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B2 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1C1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CALM3 CAMK2D â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CALM2 CAMK2D â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ATP6V1B2 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ATP6V1C1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CASP9 APAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5221774 9390557
CDKN1B CCNA2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 34591612
CREB1 EP300 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12665587 21268077 10506141 21212407 11313407 7870179 17476304 22787115 26944191 33846793
CAMK2B CAMK2D â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDK6 CCND1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15232106 16713569 10022865 24855949 17517622 33854235 11739795 14681455 24953629 11360184 33961781 10580009 17420273 21654808 11160398 9178893 19075005
ATP6V1B1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ANAPC16 ANAPC7 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ANAPC15 ANAPC4 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BCL2L1 BCL2L11 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ANAPC16 ANAPC5 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ANAPC16 CDC16 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ATP6V1E1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ANAPC5 ANAPC7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ANAPC16 CDC27 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC16 ANAPC4 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ATP6V1E1 ATP6V1F â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1F â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ANAPC7 CDC16 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCND1 CDKN1A â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
DYNC1H1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK4 CDKN1B â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CREB1 CREBBP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CCND1 CDKN1B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CDK4 CDKN1A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CCNA2 CDKN1B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ANAPC5 CDC16 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
APAF1 CASP9 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CCND1 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 25416956 25241761 8259215 9372967 29142209 9150368 18537972 16431923 33854235 24292678 9178893 33854239 9106657 14681455 8867812 8662825 17420273 19767775 16985050 19075005 12519773 21306487 26203195 24855949 23007395 11360184 10580009 11463845 17081987 8978686 16613857 15681588 21242975 15232106 9837900 24218572 27130439 10022865 25910212 9228064 12036906 23707388 23543736 27107012 23718855 19470470 31217276 10908655 8756624 25502805 17205132 33961781 20837141 19237565 21654808 11160398 7568034
ANAPC11 CDC16 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EIF2B2 EIF2B5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B4 EIF2B5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B2 EIF2S1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B2 EIF2B3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B2 EIF2B4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC5 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDC16 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC11 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 CDC16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 ANAPC7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC11 ANAPC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATM ABL1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 17303408 22334513 11375976 11804596 23331499 21071413 16163361 17570479 18988627 9168116 23847781 9168117 20798688 15964794 19788416 9561848 22084676 12607003 10212258 15459660 11877377 15686624 17409407
ABL1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22553782 24974292 29066624 15657060 20841568 28177918
ABL1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19563810
ABL1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17254966 17908796 22276948 16195327
ABL1 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12107171 20841568
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12569093 15735735 20841568
BCL2L1 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10811864 9488720 12963020 9539746
APAF1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 17145710 15829969 15024710 9390557 19494828 11113115 10617566 9539746 10364241 10722681 27476169 21060833 19118655 20829884 16977332 10329646 15210107 10393175 16352606 11242052 14555243 10376594 12773388 10206961 19337385 10428850 9488720 19788417 15262985 9922454 21827945 10749135 9651578 19698783 12792650 9837928 11227497
ATF2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9990041 10915780 11850817 11410592 11739785 15691880 16405968 10464245 10500157 15314161 10066798
ATM ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24357804 25545367 15916964 28212892 25689427
H4C6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM CHEK1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
ATM TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24366874 20023394 18769144
ATM SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23148884 18619531 22826432 27156884 29144413 29294106 23046908 17609267 18171990
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23405218 17525332 25659035
ATM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16293623 15073328 17525332 15212693 23642045 19115993
ATM CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 69.0 1.0 Omnipath 29774099 20976184 26683224 25663895 12676583 17303408 14657349 29167438 27545311 10859164 19056039 15485915 28808226 12588868 16163361 15650047 12676962 17570479 14988723 14681223 26516160 10608806 26069190 29741650 12676925 23847781 17118344 11252893 20376879 15964794 15149599 18691976 19059218 20068082 15707391 12607003 25450480 17525332 11553781 19646247 15870257 15459660 20798862 19716789 11877377 12660173 11390642 15674326 16782033 28396830 28228262 12446774 15533933 15212693 29555944
ATR CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
HES1 ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15073328 17145710 16293623
ATR CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 29774099 26683224 26658951 28180282 27545311 29605721 16461339 26165835 24971543 28937603 28573382 27713304 27643582 18723495 26082189 25205668 29088070 22971344 20536192 22353182 28051860 19276361 14681223 14988723 26069190 23892398 12676925 11252893 26643553 16520097 23383325 20396397 16431910 19059218 21440578 22357623 24753408 28572758 11090622 25795119 29309644 15870257 34398682 19716789 23508805 25965828 24947324 23380594 19071136 23118481 28396830 15533933 15190204 19737971 24023735 27283761 28025997 23696651 16360315 28915668 15707569 19062161 14657349 19489726 21937510 25448276 26721387 27558808 25104095 19056039 23468519 17081992 20679434 20062519 28808226 27679857 12588868 22203733 29928473 25459351 28558031 12766152 26748709 28986587 18265945 18669648 27775084 18691976 12781359 23583268 29221122 26633513 34509474 22564734 31928997 33863777 27685627 27167194 29118324 30796221 24366029 11390642 21907702 24632611 27068998 24349411 31591366 17686975 15665856 19781914 21736880 12676583 27690219 23386996 21482692 24113549 21730979 15775976 15272308 17851138 33811702 27271602 30510197 28273450 29209046 23849791 18794134 25024738 12676962 26438152 20932473 15279789 20376879 16414131 15149599 24387336 18790091 24327542 17525332 19646247 23997120 20798862 29022904 15674326 24500207 16137618 12446774 16885021 20639859 19101576 20976184 25663895 24244353 27603133 10859164 23333305 24621867 22863316 24072747 15650047 22084686 10859163 21851590 23613359 15629715 29741650 17118344 22706734 25565400 25301724 17327276 23006513 29242514 24906880 15707391 27908669 18353973 27708213 18243098 18603484 12660173 18955550 26039276 19473886 28255082 25898113 29163782 16629900 25937999 30100999 24140082 24970150 22084169
AKT1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
BCL2L11 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 17145710 16697956 9430630 17525735 22516262 18498746 10198631 21199865 20836993 26186194 15694340 17289999 27013495 32296183 23245996 11859372 19427863 21671007 14596824 9731710 16260615
BCL2L1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 25241761 9539746
AKT1 BCL2L11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17145710 16282323 30923040
BIRC7 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 11024045 11801603 25416956 31515488 32296183 11084335
AKT1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 11756412 11923280 16697215 20398329 18372248 15004527 15808505 20138985 20214616 15703181 17570479 28177918 18840507 15169778 11714830 10949026 16341064 11715018 18636226 10529400 9812896 17680028 19440551 10722653 20832730 18570873 17052453
AKT2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9812896 15004527
AKT3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9812896
BIRC3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16339151 21988832 9990849 15069192 25241761 9545235 16701639
SP1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10497251 22911796 19850937 9236224 17617380 9407106 15870300 22415074 10850422 9584162 10908361 22734486 16267018 9637785 19755513 11410592 11024050 15922873 12794082 20435036 22334592
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CDKN1B CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 9106657 10908655 17254966 25416956 7478582
CDKN1A CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 26203195 23443559 17145710 25416956 7478582 9837900 21988832 21516116 7777546 15232106 16082198 27107012 15695403 8657154 8242751 23007395 9106657 12383116 17556661 8756624 8662825 31515488
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
CD74 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CDKN1A CDK6 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517297 17092340 9106657 18710949 24515438 20843055
E2F3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17008321 10030670 22894933 17167174 15855772
TP63 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15790310 10383130 21480565 12640112 20123734 17404570 16007146 16410722 15965232 12374749 17965458 21093383 23665236 9405685
CEBPB CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10982390 15466360 15041706
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
AKT3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12851486 15023346 19216069 17680028 11756412 16680151 20214616 11463845 23109003 20452955 9829964 20398329 17646672 10217147
AKT2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 21933447 16982699 20452955 9829964 20398329 17646672 10217147
CDK6 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 25121590 20102411 15964852 22375140 15232106 16713569 16508017 19440234
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
CDKN1A CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 23443559 26186194 21308745 9660939 8756624 15890360 9380407 8242751 8662825 12947099 9632134 17679094 26496610
CDKN1A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23443559 15169570 18850315 9658399 16962592 15232106 9632134 16189514 8622677 15695403 20102411 8242751 9464540 23007395 7626805 9106657 12383116 30193583 17556661 23543736 8756624
FLT3 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 17254966 28522571 19075005
HES1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22311706 19541765 15870295 19598246 19609448
SP1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9349726 12907235 18355800 10072762 19145069 21131823 22415074 15064717 15951157 16105842 23184467 15899840 12773549 12907249 10542271 16518840 11231912 19433067
AKT2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12244303 18593906
CDK6 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16160006 25241761 18615582 16782892 21439954 11360184
AKT1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 22119715 11756412 16780593 11923280 16697215 16209941 12244303 20398329 18372248 14967450 18710949 15808505 26053093 20138985 14504289 20214616 12244302 17570479 18593906 23576547 23400686 12851486 15169778 24651496 19829074 25241761 10949026 16288292 11715018 18636226 19377290 9812896 12042314 17680028 10722653 20832730 18570873 12244301 17052453
CDKN1B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 23602568 8978686 23707388 21439954 18850315 16326706 9658399 14597415 18615582 10198259 16782892 9632134 16189514 17053782 11360184 9311993 17092340 20837141 26186194 25241761 15695403 9464540 19470470 9106657 10908655 23543736 11940657 18285702
CDKN1B CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 8684460 26186194 9660939 17254966 15890360 16209941 12947099 12501191 26496610 9724724 9311993 9716181
CEBPG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12177065 8530498 15223809 8413306 20388952 8207232 9271387 18824136 18199703 18850010 19734226 8999951 12561382
AKT1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20832017 18691976 23108403 17418864 20068231 12062056 15107605 17570479 19664995 18669648 26091525
FOXP3 CTLA4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12522256 17237765 17449799 21411734
FOXP3 CTLA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18599122 17028180 20554955 21654845
CEBPB CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17656649 19962993 23098564 25453873
SP1 CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15808852 23246486 21465475 19745163 23098564
EIF2S1 EIF2AK3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 18664456 12370288 16288713 17956313 11907036 10026192
EIF2AK3 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 76.0 1.0 Omnipath 25429617 25579745 14967143 17998059 21981022 27009865 10504407 23356742 3352609 26622781 24316205 24706853 16288713 20408811 30070006 18840095 27638465 21844328 21029306 23293645 21901118 29199180 30081573 14638860 19007793 9819435 23935851 8099443 21029301 19220912 31226023 25660019 22509299 22169477 11337501 24904562 15314157 9930704 23314846 17998206 17325203 16179258 25393282 19583950 26028033 29396442 26487695 10542257 18694499 1677563 11555640 24705207 20040105 24159375 25541374 24958502 11907036 29163417
AKT2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17964260 16926151
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
AKT1 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17081983 32028981 33911076 26318844 33151228 20844753 27591085 17704806 21423216 19036157 31906126 15806160 24335958 34272387 33379356 19651622 31387591 16354698 19664994
FCER1G FCAR â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
FCER1G FCAR â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
SP1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10792620 10644332 17255531 8630731 10636866 16847329 10657660 23349788 12787135 12488502 12682245 25108845 8051410
CEBPB CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17180354 10748205 20019816 12145301 16784777 17390372 18649942 20730378 19026986 15710476
CD40LG BIRC3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
CD58 CD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30368623 23602662 16189514 7544396 21982860 11575926 7525848 1377404
CD59 CD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16189514 1385156 1377404
CEBPB CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11937564 11413310 12388374 16239564
CREB1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11413310 12388374 7513046
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
CEBPB CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23051921 10775602 17135982 8969274 17997161 18512730 21471847 24554449 14645117 15085176 17845418 12707271 12748173 19489038 22031759 8234276 19064995 8207232 16989899 27856305 11991987 19109189 17471497 19786303 16809637 16818736 21255844 19734226 24038085 18772138 19805069 20861254 18487355 11390611 15688424 10462040 16803583 8999951 11120852
DAXX FAS â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
DAXX FAS â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
DAXX FAS â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
FAS DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 15725726 9743501 25241761 11483955 11773067 11003656 14637155 11193028 11495919 9215629
SP1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10022897 9261184 22084312 9300785 10871852
EIF2S1 EIF2B2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2B2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2AK1 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 28781602 10504407 3352609 11041858 24706853 16288713 28670265 2116318 9819435 8099443 15550948 11337501 9930704 16179258 19583950 10542257 10563826 1677563 24714526
CEBPB CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17067998 8654374 10818089 15722556 15388792 17599912 12857754
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
CREB1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 10866654 18599546 15585582 7870178 8028671 11313407 16007092 8413673 11564156 15691881 9829964 15073328 20403362 11259575 17476304 17707401 20541704 16799563 7870179 11123304 27789289 7913207 12933667 8663317 8004670 11483993 12198160 9413984
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
CD4 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
GATA3 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24167278 19542428 23310955 19602726 20696860 24813204 18776904 20706986 20809492 20065998 19801513 21341258
ESR1 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11773442 17535799 15033483 22031296 15496458
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
SP1 CTSL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11742542 14563703
SP1 EPOR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21029371 7659529 23577103 8521844
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
SP1 ALOX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16413224 2251250 9698605 17894944 23720274 20554538 19781662 9062372 16364163 10436859
ETS1 GP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15466856 11504709 10194443
CAMK2B ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12475968
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
EGR2 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23155406 18396140 16054051
EIF2B4 EIF2B2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25910212 10805739 31515488 16189514 32296183 9446619
CREB1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11160720 20857405 8641461 17325033 12869629 19343785
AKT2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
AKT3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
CAMK2D CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11175347 12356771 15733869 22554507 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK2B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
GNAI1 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9748257 23109003 15539636 7935349 16460834 11376933
E2F3 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15510213 11980909 10733529 18319725
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
AKT2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11139588 11432835 11507039 9528769 7838153
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
CDC16 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
CDC27 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
CAMP FPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11015447
HLA-DQA2 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 CD3G â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
EPO EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 8662939 9442088 15358619 9030560 9974393 9774108 18586265 23331499 2163696 10318834 21889455 17327410 16982323 29997244 9808045
CD3G CD1B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 18037897 26300885 15864273 14764708 20080535 15723809 7542404 21167756 22006319 25703557
GATA3 H4C6 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
ADCY5 CAMP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 15539636 7935349 16460834
C7 CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
CD59 C9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 7523406 1377690
C9 C7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145