Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CFHR1 ENSG00000276911 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFH ENSG00000276911 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ENSG00000276911 FHR2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFH FHR2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFB C3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 809512 279011
CFB CFH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1067618 301546
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
FOXO3 SIRT1 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome 14976264 23665396
GRB2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JUN SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
JUN VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15930183 17121851
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
ZBTB16 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
VDR SMAD3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11278756 10037600
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
C3 CFHR4 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CFHR1 C3 â—¼   PHYSICAL_INTERACTION ✅ + 0.83 0.83 Signor 27814381
FOXO3 EP300 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 11896584 19592618
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CFH CFI â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CFH PTX3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EP300 VDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 21988832 20089040
FOS SMAD3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9732876 21829441
SMAD3 FOXO3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24920680 15084259 21532621
C3 CFI â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6607952 21788512 2971659
CFH CFI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26806831 9291131 1401896
EP300 ZBTB16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15964811
SMAD3 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10903323 10220381 11306568 21829441 9732876
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SIRT1 FOXO3 â—¼   DEACETYLATION ✅ - 0.9 0.9 Signor 24003218
CFH CRP â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CFH CFHR1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CFHR1 FHR2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
FOXO3 SIRT1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
C3 CFHR1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
C3 CFI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
C3 CFB â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
C3 CFH â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CFI C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16023208 1401896 26806831 9291131 8648130 2141838
CFH C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16023208 19050261 11367533 21979047 21317894 9988761 16612335
PTX3 CFH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19050261 28533443 22786770 19632990
CFH SELL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1037724510377240 10377245
CFH CRP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20042240 17293598 17399790 19680263 21930971 28533443 17339482 10490997 18786923 29374201 26961257 19850925 19084272
CFHR1 CFH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8663389 16189514 27814381 19528535
IFNG EP300 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
FOS IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19285436 16713974 7759501 8756632 12842891 12432566
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
JUN FOXA2 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 16054035 16396903 16406505 16880536 17000779 17439715 18813803 19190345 19219074 20107231 26587781 8545107
FOXO3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23525956 20816089 15604409 23262029
SIRT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 24003218 14976264 14980222 15126506 21713995 15917664
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
SMAD3 IFNG â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 18768831 21042762 21614932 22331441 23390297 6357187 8515656 8871614 9389648
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323