JUN
|
TSLP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
TSLP
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11418668
10570284
|
TRAF3
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
BIRC3
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18997792
18997794
|
RELA
|
MAP3K14
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15047705
22685329
|
MAP3K14
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18439422
|
JUND
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11973337
14686613
|
JUND
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
JUN
|
JUND
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8922393
2504580
|
JUND
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12226747
21734453
|
TP53
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19416861
22509910
|
IRF4
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11533227
14581002
|
JUN
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12832543
11192249
|
NFKB1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18031796
|
MAPK8
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16306447
|
TP53
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
CCR2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
BIRC3
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23070005
18485876
|
NFKB1
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9294162
9733516
|
TP53
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16917513
|
EGR1
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24337575
18281687
|
REL
|
CD28
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7486663
9199340
|
HLA-DQB1
|
CD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
11535811
|
TRAF3
|
CD40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7527023
5220338
|
TFE3
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14962802
11818452
|
NFATC2
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8530342
15314684
|
EGR1
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16393964
19032775
|
CD80
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12670391
8621607
|
NFKB1
|
CD80
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12860928
11359799
|
NFKB1
|
CD83
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19164127
12182451
|
RELA
|
CD83
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19164127
|
CD86
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12670391
8621607
|
NFATC1
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16498406
11509589
|
STAT5A
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24204704
18945591
|
NR3C1
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15826950
11509589
|
TP53
|
EGR1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216887
14744935
|
PIK3CA
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FOS
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
STAT5A
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9885561
10512880
|
FOS
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20188076
|
FOS
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12163680
11353786
|
FOS
|
ICAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11356008
9218873
|
FOS
|
NFATC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15073183
23619911
|
FOS
|
NFATC2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
18172215
0705181105
|
FOS
|
RELA
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
18172215
0705181105
|
MAPK14
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18253836
|
RELA
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
10488148
|
RELA
|
GATA3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20660789
|
NFKB1
|
GATA3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20660789
|
GATA3
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19674970
11397697
|
NFATC1
|
ICAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19351910
|
NFATC2
|
ICOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16880206
17986443
|
IRF4
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21816905
20674401
|
NR3C1
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9510064
2159467
|
IRF4
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21890374
12374808
|
TRAF2
|
IRF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
RELA
|
IRF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17018379
|
TP53
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
JUN
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
MAPK9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
RELA
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17310108
10646503
|
MAPK9
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
JUN
|
MAPK10
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
JUN
|
PTGS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17138645
|
MAP3K1
|
MAP2K4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6548305
9808624
|
MAP2K4
|
MAP3K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7855889
7997270
|
MAP2K4
|
MAP3K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6548305
9808624
|
TP53
|
MAP4K4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15958553
17113036
|
MAPK11
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23602568
21900206
|
MAPK8
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19737086
|
TRAF2
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
10490605
|
NFATC2
|
NFATC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19564342
11786533
|
RELA
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211837
10498867
|
MAPK8
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
TRAF2
|
TRAF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
TFE3
|
TFEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
EGR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
JUN
|
JUND
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25609649
|
AKT1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
TRAF3
|
BIRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33608556
20097753
30561431
23524849
|
NR3C1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
TRAF3
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23612708
20097753
33608556
23524849
|
TFEB
|
TFE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
9806910
26496610
28514442
33519497
|
CD86
|
CD28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
7513726
21931534
11021528
27708164
|
MAPK8
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
7148309
19527717
|
MAPK8
|
NFATC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
MAPK8
|
NFATC3
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
14517246
|
MAPK9
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9405416
|
MAP3K14
|
TRAF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
APP
|
CRYAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
PTGS2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BIRC2
|
TRAF2
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
20651737
|
MAPK14
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
MAP3K14
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
BIRC2
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
MAPK8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
MAP3K1
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
MAP2K4
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
FOS
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
REL
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
FOS
|
JUND
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
BIRC2
|
MAP3K14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19284370
18022362
|
JUND
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11160303
|
JUND
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1737937
7989759
11685114
|
STAT5A
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8683106
9831114
7796811
|
ADORA2A
|
CD40LG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
17371980
17909080
18758473
|
ADORA2A
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
17371980
17909080
18758473
|
ADORA2A
|
IL2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
17371980
17909080
18758473
|
NFKB1
|
BIRC2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
21725609
23178297
23572150
|
REL
|
BIRC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9372964
12414938
10049645
|
TP53
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22804246
23666675
20406462
|
CD28
|
CD80
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7964482
7545666
21982860
1847722
2164219
|
EGR1
|
CD28
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11342633
10510368
|
FOS
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11160303
|
GATA3
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18719603
|
REL
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11160303
|
NFATC2
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8668213
22911897
10330159
|
EGR1
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9053449
10671503
|
EGR1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19915002
8900159
|
MAPK14
|
F3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23195225
|
JUN
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9468519
16271621
|
JUN
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16713569
7823959
8733011
|
MAPK9
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAPK8
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP2K4
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAPK11
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RELA
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TP53
|
MAPK14
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11437382
15132979
14570892
|
MAPK8
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16648474
10978313
11274345
|
MAPK9
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16648474
10978313
11274345
|
NR3C1
|
NFIL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19805059
23425966
|
NR3C1
|
RELA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12734399
9261164
9442377
|
TP53
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11080152
16713569
|
NR3C1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
8878484
9528750
|
NR3C1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11080152
16713569
|
BIRC3
|
TRAF2
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
18997794
|
NFKB1
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
BIRC2
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
TP53
|
JUND
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.93
|
0.92
|
PKG
|
28854368
|
MAP2K4
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
JUN
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
CD40
|
CD40LG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
JUN
|
MAPK10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
TRAF2
|
BIRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16891304
33961781
23524849
20184394
24276241
21331077
11907583
8943045
19815541
9384571
23007157
8548810
20447407
16713569
16282325
30561431
32296183
25681446
25716317
19584093
21988832
8643514
19506082
28514442
30359437
15861135
16189514
20348096
21653699
20562859
21903422
25241761
10753917
11181075
16263936
27534557
25882049
|
TRAF2
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16891304
33961781
15310755
23543740
23524849
21331077
11907583
19815541
9384571
23007157
8548810
30948266
16713569
16282325
20385093
21988832
24464131
8643514
20562859
25241761
10753917
27534557
|
BIRC3
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CD40
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
JUN
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CD40
|
TRAF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
BIRC3
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
FOS
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
TRAF1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
JUND
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
33961781
12193410
35140242
11431474
20195357
26496610
25609649
20102225
26186194
24029232
15867431
28514442
|
JUN
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
EGR1
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8175747
7896852
12107072
|
CD40LG
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
CD40
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
CD28
|
MAP3K14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10426994
11907067
1313950
15197224
15536084
16713974
22437870
7523569
9359474
|
TRAF1
|
MAP3K14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16713569
11278268
15084608
|
TRAF2
|
MAP3K14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
9275204
11278268
23543740
18997792
20385093
25416956
15084608
10755617
16713569
9334169
25246529
20348096
20651737
20184394
9020361
|
BIRC3
|
MAP3K14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18997792
19284370
20682767
|
TRAF3
|
MAP3K14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
17145710
18997794
9275204
15208311
11278268
23543740
18997792
14743216
15084608
32296183
25246529
20348096
|
RELA
|
CXCL8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15079071
15536066
17550372
19171876
23430059
8383323
9743347
|
RELA
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
129.0
|
1.0
|
Omnipath
|
12820969
24337575
15289496
9405619
9698090
20038977
15057743
21665565
24260304
10817569
14631383
10969814
15005855
19668231
16325549
19732956
8207232
18281166
27856305
23894194
9388261
26340924
10975857
10745031
20194077
10928981
16553947
17565687
16764699
22848596
15531761
16105834
16803583
9510190
15355994
18221537
12643600
20053934
11716760
8617886
12218154
12707271
23637609
27076634
8878392
17917246
12163591
16829531
16818736
14670967
12038622
15958549
18362169
8413215
19734226
23386688
11297551
15950427
17362989
16455661
27371733
11953364
8413306
18074095
11973337
18786178
19376732
19837667
17276517
15517885
11342414
18669446
7876168
15350531
14645117
22891766
18034886
11564889
12748173
17586662
18996370
15223809
17041011
12485925
16004996
15079071
21343296
26618242
18435575
17636245
22340043
19173296
24634218
11120852
10477716
21343177
12058956
17045242
19786024
24048734
24770886
10202011
18309103
11864912
21131967
19064995
10530453
12716652
16418726
28283022
18723827
17040605
21255844
15615716
17932106
19966855
20696864
15387324
21451502
15722553
15879558
12855659
12883201
15688424
18045535
10506755
|
JUN
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
18684922
16701870
24048734
14686613
24284797
15057743
12643600
17197543
11864912
10817569
12218154
22031759
17586662
10969814
19064995
12716652
27856305
25582859
17471497
22095787
16818736
23176534
14670967
18435575
16846747
19734226
16299055
14612204
18772138
19132242
12209633
15939312
16834785
11399048
11120852
25567680
|
NFKB1
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
9510190
12058956
11973337
18786178
17045242
15289496
16701870
19376732
19837667
9698090
17276517
11512674
19786024
20038977
10202011
15057743
15517885
12643600
11342414
7876168
15350531
18034886
11716760
11564889
11864912
12218154
12707271
10969814
12748173
14631383
16325549
17586662
18996370
19732956
17041011
10530453
18281166
12716652
16418726
12485925
16004996
9388261
8878392
17917246
10975857
10745031
10928981
16553947
16818736
14670967
18435575
12038622
15958549
17040605
8413215
21255844
22340043
1401924
9452482
16764699
11297551
15950427
15387324
15879558
16105834
11953364
15688424
18074095
8413306
11096450
16803583
10506755
11120852
10477716
|
NR3C1
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
24500711
27371733
15879558
19307749
15355994
21474440
1592440
|
FOS
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
11973337
18317936
12218154
22095787
12748173
10969814
15005855
17586662
16818736
24048734
14686613
16846747
15057743
15615716
8999951
25567680
19173296
|
MAPK8
|
JUND
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16007120
22327296
14676207
12052834
26538579
|
RELA
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7957928
15331713
9446577
8035474
|
NFKB1
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7957928
15331713
8035474
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
RELA
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20186924
18031796
20649564
|
STAT5A
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24218138
24469394
18042802
20385773
|
PIK3CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25793261
19117013
21041639
24950409
21816939
|
AKT1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
15911620
15998799
17570479
30680530
11707464
|
AKT1
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
27997540
24291004
|
APC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11274345
11955436
11967263
12051714
12711682
15001769
15327769
15834423
16039586
16510874
16547505
16940750
17143292
17439715
17936032
19216735
19506021
19619488
19623618
19751508
20006983
20705860
20964627
21285352
21681822
22270359
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
APC
|
JUN
|
â—¼ SHARES_COMPLEX
|
|
|
33.0
|
1.0
|
ACSN
|
11274345
11955436
11967263
12051714
12711682
15001769
15327769
15834423
16039586
16510874
16547505
16940750
17143292
17439715
17936032
19216735
19506021
19619488
19623618
19751508
20006983
20705860
20964627
21285352
21681822
22270359
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
JUN
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8063812
11677255
8015372
|
MAPK10
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8131745
14970211
22958823
11877420
24610780
15936948
|
MAPK8
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12917434
14970211
24610780
20122754
15936948
|
CD40
|
BIRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
CD40LG
|
BIRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
NFKB1
|
BIRC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15050749
17673602
12687011
15756023
9733516
12010810
18566231
16453001
20103608
|
RELA
|
BIRC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15050749
17673602
12687011
12714587
15756023
12010810
18566231
16453001
20103608
|
TRAF2
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
21653699
25681446
8943045
8643514
11907583
16713569
20184394
18621737
18997794
21988832
25882049
9384571
21903422
16891304
10753917
20447407
18981220
16189514
15861135
11181075
20348096
20562859
25241761
19584093
32296183
21331077
23007157
16282325
19506082
25716317
23524849
24276241
16263936
12887920
8548810
19815541
|
CD40LG
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
CD40
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
NFKB1
|
BIRC3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
21725609
23178297
23572150
9294162
9733516
|
NFKB1
|
BIRC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15231833
15050749
19343319
17673602
17000776
11880364
10733571
9733516
18566231
12010810
15723831
10823821
11297551
|
RELA
|
BIRC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
15231833
15050749
19343319
17673602
18226221
23250755
17000776
11880364
21279667
21765477
10733571
18566231
12010810
15723831
10823821
11297551
16291753
|
REL
|
BIRC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12414938
23271966
11880364
|
TRAF2
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
18997792
8643514
11907583
16713569
18621737
18997794
21988832
18606850
9384571
16891304
10753917
18981220
24464131
20562859
25241761
23543740
20385093
21331077
23007157
16282325
23524849
8548810
19815541
|
CCL2
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10623817
15032599
17681149
19915063
23527025
23567181
23943801
24531940
27216177
|
FOS
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18024959
18443042
14752027
8063765
12667961
17424890
7602115
9558097
16206198
19404962
|
NFKB1
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10644332
22189654
20038977
11512674
8630731
12488502
12540607
11716760
8617886
12218154
14631383
16325549
10744656
10530453
11006087
16040075
10987310
16206198
9388261
10614622
16818736
10636866
10469356
17507908
12647268
16764699
25108845
20200316
15950427
20579762
11949945
|
RELA
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
24337575
10644332
22189654
18226221
20038977
8630731
12488502
19738286
22189669
14976218
19371341
12540607
24260304
11716760
21138578
8617886
12218154
14631383
20952659
17452470
16325549
10744656
15223809
10530453
11006087
16040075
16730843
23583295
24063814
27076634
10987310
16206198
9388261
10614622
18353872
16166627
16829531
16818736
10636866
20195282
10469356
17507908
12647268
12682245
21106671
24550391
16764699
17932106
25108845
20200316
15950427
24634218
9174597
23198981
11949945
9916692
17537731
22723832
|
REL
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10614622
11716760
12218154
16325549
20038977
10469356
9388261
|
JUN
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19162185
18024959
18443042
14752027
22674286
23583295
19299558
12667961
10918580
19371341
26554515
|
CCL2
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
10770925
10488147
10699158
22633458
9169459
11470772
28389721
9336350
8530354
15629146
11310855
9276730
20219869
9115216
9346309
9312096
9837883
10529171
15207250
9287323
12554737
7759884
|
CD86
|
CD28
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10477595
11207245
11964292
14764699
15034038
15197224
17513775
20231889
20805416
21220452
22076556
22437870
23390297
24218453
25215878
25384214
7523569
8920882
9359474
|
CD80
|
CD28
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11964292
12810107
14764699
15197224
17513775
17629517
18585785
20231889
22437870
23390297
25215878
25582338
26405600
7512027
7523569
9359474
|
CD28
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10426994
11907067
1313950
15197224
15536084
16713974
22437870
7523569
9359474
|
CD80
|
CD28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
21530327
7964482
22437870
2164219
1847722
23954143
15610849
7545666
21982860
21487479
|
CD86
|
CD28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21530327
22437870
18205792
23954143
11021528
21931534
21487479
7513726
|
NFATC2
|
CD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21799768
10692237
17463169
16880206
16219537
9916709
10799559
|
GATA3
|
CD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24167278
19542428
23310955
19602726
20696860
24813204
18776904
20706986
20809492
20065998
19801513
21341258
|
CD40LG
|
CD40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40
|
CD86
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40
|
CD80
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40
|
CD70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
NFKB1
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17513725
11313274
19164127
11027342
17031478
9733827
|
RELA
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11313274
17031478
19164127
9733827
10075983
|
NFATC1
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21913318
21413932
19801646
23990468
20831919
|
CD40LG
|
CD40
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
1280226
1374165
19426221
7516405
11163401
7543281
12324477
10647992
17183360
|
CD40
|
TRAF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
20614026
17145710
21041727
9133417
7859281
12637493
10352240
16260598
15485859
24810049
17878343
9384571
7530216
12220533
18635759
14517219
9990007
24260396
10428814
17332487
19667091
7533327
9168896
10984535
27716849
9718306
10318845
11562359
7527023
|
CD40
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
20614026
21041727
9133417
25416956
12637493
10352240
16713569
16260598
15485859
25502805
12220533
18635759
25910212
9990007
17353931
8855313
10428814
21282461
10411888
17332487
32296183
16282325
20676093
19667091
9168896
27716849
20449947
9718306
31515488
10318845
21071692
11562359
9020361
|
CD40LG
|
TRAF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
ICOS
|
CD40LG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10426994
11907067
15536084
16713974
20116985
21708958
|
CD40LG
|
CD80
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11581322
15034038
17200410
17371980
23125331
8760829
|
CD40LG
|
CD70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD86
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
NFATC2
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17237447
18719603
|
NFKB1
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11751888
11529914
21243522
11160303
|
RELA
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10369418
11529914
21243522
11160303
|
CD80
|
CD86
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10477595
11207245
11964292
12810107
14764699
15034038
15197224
17513775
17629517
18585785
20231889
20805416
21220452
22076556
22437870
23390297
24218453
25215878
25384214
25582338
26405600
7512027
7523569
8920882
9359474
|
RELA
|
CD86
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10586028
12574356
15949284
19164127
15895390
18929846
|
NFKB1
|
CD86
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10586028
15949284
19164127
15895390
18929846
|
TP53
|
CRYAB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19343786
24859470
19777343
21556774
19799611
|
RELA
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9414129
7636192
9190901
11418664
18230685
9596659
8135780
21071440
14741709
11395507
8934574
18285351
10608823
18056447
|
REL
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9414129
11418664
8152309
8662666
8934574
8660380
9185524
24899500
|
JUN
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9190901
12760745
19890352
1900839
8135780
11509589
8524292
7579683
10330159
9862439
15840658
|
FOS
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9190901
1900839
8135780
11509589
9028942
12432566
7579683
8631792
9862439
|
NFKB1
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9190901
11418664
12760745
8135780
8934574
14741709
18285351
10608823
|
RELA
|
EGR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19276347
20427719
15616591
21983014
|
EGR1
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19915002
10656874
12560487
9756940
7673240
20680391
8773576
17142725
|
EGR1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9049304
19526316
20489156
15517885
15737464
|
EGR1
|
F3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11594561
10674404
10551840
19652887
17967787
8576248
12600889
12483323
10339488
16037570
11520792
20671239
10707957
11978801
16849552
15492129
9653181
10329706
8647847
|
EGR1
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15517885
20624458
20546888
17032742
|
EGR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9242687
17822668
15958557
12755686
16990849
|
RELA
|
EGR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19915002
19837667
10671503
|
EGR1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15225550
14744935
11251186
16713569
12384981
|
JUN
|
F3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23038262
11057875
20671239
15201277
15636197
7615158
9585253
9081693
8647847
14603525
|
REL
|
F3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11057875
7615158
9081693
|
NFKB1
|
F3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15242552
20303465
11057875
12746898
9867853
19167713
11157486
|
RELA
|
F3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15242552
11057875
12746898
9867853
18226221
19167713
7615158
7929355
9081693
11157486
|
JUN
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10606235
11274345
11274400
14673140
15067049
16393692
16394015
17439715
18222063
18754863
19667062
19846528
21385848
21790308
22381618
22634314
22723415
23430059
26587781
8545107
9064320
|
JUN
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
2513130
14561487
8617996
8934539
19255142
9217081
12760745
2498806
10521486
8597411
10858536
12392213
9819441
1380150
23562910
1944274
9867253
9571041
1900040
2511006
14684847
15467742
12231642
11950097
|
TP53
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
8604347
17174366
8668332
1946467
10082525
10214938
1508692
8649776
10529369
12173040
|
NR3C1
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16850320
9804760
1314076
8036015
8890955
8733011
|
FOS
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19285436
16713974
7759501
8756632
12842891
12432566
|
FOS
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15772294
11278336
9620167
17556653
12057991
8906578
17440114
|
FOS
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
20557936
8893011
11260070
11685114
8397339
1737937
9605137
9590239
11262396
7989759
1916630
8473495
10601992
8114694
22474330
18725523
9233628
11385624
2518655
15170389
8468462
7565732
12432566
8660843
7739550
1305903
20680391
19181930
|
FOS
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
20498278
16714286
21675959
25609649
23602568
9872330
20102225
8380166
18848838
18535250
2516828
8397339
15867431
18172215
9346889
10779323
9732876
16928824
26496610
15994313
22719067
24029232
16511568
20195357
11053448
20936779
26186194
18619508
20511396
16008525
10488148
21199371
8617242
17440114
16055710
15319445
11090181
9160889
23661758
1631061
15718494
11431474
31515488
8440710
7816143
20410304
34671206
|
GATA3
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17717199
20399120
11970994
21507199
20193034
23232398
20636338
21632975
8228802
19648923
15251440
16520391
|
IFNG
|
ICAM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
NFKB1
|
ICAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
10926553
15480988
9192770
7957928
11198351
19074768
9188493
16317091
17121934
18928584
15843586
22001597
9056676
18285351
16385502
10946302
20103608
10738944
15800027
22708120
9888295
11877286
17855547
10553096
10092659
9733827
11401521
11463837
9916895
20173029
10837365
12691701
16105834
12490396
16453001
|
JUN
|
ICAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11356008
12832416
9218873
20459645
|
REL
|
ICAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10926553
10837365
9056676
10706725
7957928
9442377
|
RELA
|
ICAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
10926553
7822333
9192770
9831247
7957928
15996193
22337883
19074768
16778171
9188493
16317091
17121934
18928584
15843586
22001597
9056676
18285351
16385502
10946302
15946255
20103608
10738944
15800027
22708120
23238746
22901690
9888295
11877286
7659084
17855547
10553096
10092659
9733827
11401521
11463837
9916895
20173029
10837365
16455661
19351910
20823682
12691701
16105834
12490396
17537731
22345292
10228026
16453001
19278584
|
IFNG
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
48.0
|
1.0
|
ACSN
|
10485906
10679398
11489965
11579131
11777960
11870632
11964313
12133954
12413632
12759422
12818165
14607900
14668329
15079071
15536066
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17145890
17404308
17550372
17559085
1825141
18272812
19171876
19833085
20038811
20138012
20819927
21149606
21224476
21411734
23430059
24658051
26755705
2965306
6425450
8383323
8580069
8641346
9743347
9834059
9864217
|
JUN
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20006311
22123848
14734615
15187132
11943142
20304822
17556653
1314139
17105733
22413812
19265145
11801649
16713974
7759501
12836278
15522880
12626576
9558063
8756632
18641343
22351517
|
REL
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9374532
16481345
23195252
1542667
17012234
7957928
|
NFATC2
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23616576
18962896
15684054
12836278
22123848
11520798
12842891
18217957
22427656
22844476
10894164
21624129
16237086
|
NFATC1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9374532
11994444
12842891
12836278
|
RELA
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17035338
12759422
12105194
21243522
9374532
10227974
20643337
19929594
19732956
21224476
23195252
23667107
12842891
14662860
12757742
18690006
17407192
10075983
|
NFKB1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12759422
21642544
21243522
9374532
10227974
16481345
17556653
19732956
21224476
14662860
12757742
18690006
17407192
|
STAT5A
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12759422
7875295
7796811
15528362
9831114
|
RELA
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10679398
12133954
12759422
14668329
15079071
15536066
17145890
17404308
17550372
19171876
20138012
21224476
23430059
8383323
8580069
9743347
|
NFATC1
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
16498406
20557936
17179947
21832163
15005855
17513763
7730629
8631809
10656874
12560487
8202141
18097033
9756940
8543769
8660843
7739550
23924068
15347678
19564342
19181930
18769450
|
JUN
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
20557936
12370343
10700231
12884855
8436291
9541574
8397339
1737937
9605137
8683110
21832163
9590239
7989759
9774418
16116194
8473495
8114694
10878360
10320367
9233628
7642615
17097050
7565732
8468462
8660843
7739550
8051409
1740667
19181930
|
NFATC3
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7739550
9017603
21642596
17513763
7730629
8543769
|
NFKB1
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
17641034
1777483
7623820
7744006
8834450
15477007
8254209
9111330
9135552
8383323
11035116
7730629
15079071
2848811
9737979
1707162
19968887
7957556
1604322
8977179
12027419
17491020
18207244
8814256
9233628
11145913
|
NFATC2
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
15180435
20557936
8576111
8014029
8397339
7706710
21458306
21832163
8577772
17513763
16873067
8631809
11956291
12560487
17237447
24561192
18097033
7565732
8668213
7982959
21799768
8441422
9047239
8098881
1712901
|
RELA
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
7623820
8814256
22427656
9417120
9605137
15477007
9111330
21832163
9135552
8383323
8934574
11035116
7730629
16275766
9737979
19968887
28199730
1604322
15585831
8977179
12027419
18045535
18207244
17179947
23578476
15710339
9233628
11145913
|
STAT5A
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9817603
24587342
7479881
8683106
24550509
10022878
8943338
9121484
17911616
22854263
17182565
11435608
|
REL
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17641034
7623820
22860011
11917142
11313336
7744006
17182554
9605137
21832163
8383323
8934574
21890374
8670878
21371435
15079071
9233628
27898347
8977179
8152309
11254713
8920856
16585559
7969133
8814256
7982907
12646638
9547358
24853588
|
NFATC1
|
IL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17928811
16406523
19218564
20452955
|
NFKB1
|
IRF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12218129
17018379
16272311
|
NR3C1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20499359
8639160
2169353
9731701
|
JUN
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
11901151
16001969
19783677
15238218
23523690
10668496
16007171
12057991
22472290
18294142
16339564
17556653
9830045
9988750
19825968
15994313
15772294
9620167
9686761
15525691
11356200
16256955
11234900
18097055
11980644
9705326
19522015
11278336
18282182
12086396
10811116
20237399
|
JUN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22859294
17321721
20697347
10348347
12963547
10072388
22353755
18604200
|
JUN
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9256279
11204570
11353786
23274526
11678207
17341624
20015448
8910439
16328781
11731421
15039660
19553068
20432243
7887961
12163680
10885623
11281649
14602779
18294451
15277220
|
RELA
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18174238
9468519
16713569
10488148
|
MAPK14
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12475989
17689131
17570479
25483191
|
MAPK8
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
202.0
|
1.0
|
Omnipath
|
17143273
17804415
10617656
8846788
15958389
11948398
10882101
20028971
12697749
15894542
20514406
14612408
17875713
9891069
17570479
18922473
11809792
8586671
11896587
12185592
12871843
7992057
7600582
11278395
8137421
8001819
10493750
14557262
16549498
18707149
9169478
11460167
15289320
8157646
16007099
20506250
22110360
15378002
9687508
12740383
20732415
9305638
19270716
23331499
10747973
16291755
16393692
12832416
18988627
10713700
18669648
12087092
14633987
8525045
15677475
16076903
16166642
18650425
15590691
1608942
19910486
18212344
11562357
12228228
16740711
14701799
19690332
10871633
12531896
16713569
8654373
16983342
19664995
15302935
10962563
15068801
8621542
8607977
18362184
10393177
20068231
9808624
14572659
8224842
10585392
9407028
17363973
19527717
19436832
14517282
12407442
9487126
9692890
14523011
15212693
10908726
11108663
13130464
10064600
18429822
15299005
9774977
11907583
12963725
16824735
19413330
10617104
17055484
21071413
18452278
16434970
16157600
7737130
23816567
10987838
17189706
9561845
9575168
1460037
7652575
18617513
24113186
11971971
11801649
25098452
20058876
16533805
9184210
18003900
9315636
10385525
18957422
12881422
11274345
12052834
15749833
|
MAPK9
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
17143273
17145710
17637567
12584171
20506250
11948398
15378002
16824735
9687508
8654373
20028971
12788955
9305638
15302935
26091349
33822843
18362184
17875713
16393692
9405416
17570479
1922387
18252863
25561726
7737130
10490605
17189706
11896587
34408980
11274345
20178741
8525045
16076903
7992057
19527717
7600582
17215518
8985011
11801649
19118012
11278395
8001819
8137421
19436832
16533805
8945519
12881422
9315636
10385525
12093796
14523011
19910486
15212693
8157646
12040039
11562357
|
MAPK10
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17143273
20506250
16824735
8654373
20028971
16007099
21988832
12167088
16393692
1922387
16076903
22327296
19527717
21757544
19436832
17670986
14523011
11274345
20395206
11562357
|
TRAF2
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
15592525
17462996
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
|
MAP3K1
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
41.0
|
1.0
|
ACSN
|
10086337
10465784
10567412
10811803
10982827
11274345
11447289
11668179
11777939
12040186
12048245
12175651
12419216
12640133
12738796
12782630
14585353
15170913
15567848
15574420
15863030
16102570
16227978
16488589
16582911
16887996
17496910
17496911
17673906
18855897
19449109
19568798
19615955
21102635
21614932
24027568
26552706
7510700
8551221
9379049
9582321
|
MAP3K1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
83.0
|
1.0
|
Omnipath
|
17145710
15863030
8551221
10811803
11447289
16582911
11777939
18855897
9379049
16472679
12640133
12040186
9305638
26552706
23331499
12048245
10982827
16227978
11668179
23180781
21614932
9808624
12738796
12782630
9889102
9891069
10567412
12175651
18182252
19568798
16102570
9582321
14585353
10521444
17673906
17496910
11242034
10465784
7510700
9712898
11274345
12419216
7992057
7600582
10086337
17276500
15574420
19449109
26192618
19615955
19369195
24027568
10400627
16887996
8910292
12456688
9487126
21102635
15567848
17496911
16488589
15170913
|
TRAF2
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12655147
21614932
12738796
11274345
18855897
|
MAP2K4
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
17143273
10713157
11489946
7600581
8702918
17145710
13130464
23416355
10748139
8805275
18855897
10791986
9108083
19690332
95141073
18083107
9724739
12788955
9305638
23331499
19534553
15068801
7839144
10958661
21071413
23047924
11062067
21614932
9808624
12738796
15911620
15998799
9891069
11389443
18988627
9733714
11847100
18669648
16153436
10521444
15302099
16282370
11242034
14523011
12709432
26370088
9661668
10499589
7652575
16076903
7992057
16440308
7600582
17192257
9860979
15755722
12133933
16533805
19369195
9312068
9207092
10385525
12354380
12917261
8910292
9487126
9448004
10962008
12624093
11274345
11099046
|
MAP2K4
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7914033
7535770
7839144
9808624
7693711
7716521
7997261
12788955
26538579
|
MAP2K4
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
17143273
11489946
10748139
18408005
18855897
17761173
18083107
8974401
12788955
10715136
23331499
23047924
11062067
21614932
15911620
12738796
11389443
18988627
12624093
11847100
11242034
26370088
16076903
12133933
19651622
12354380
14523011
11274345
|
MAP2K4
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17143273
7600581
11489946
10748139
18855897
14699111
10791986
17761173
18083107
12788955
9305638
22730327
23331499
19534553
23047924
11062067
21614932
12738796
15998799
11389443
18988627
9733714
11847100
16153436
21900206
11242034
14523011
26370088
10499589
16076903
7992057
7600582
9860979
17192257
15755722
12133933
19369195
9841871
10385525
12354380
9448004
12624093
11274345
11099046
|
TRAF2
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12738796
14730360
15170913
15592525
17462996
17496911
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
9379049
9582321
|
TRAF2
|
MAP3K1
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12738796
14730360
15170913
15592525
17462996
17496911
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
9379049
9582321
|
TRAF2
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10346818
17145710
25241761
16636664
10755617
18635759
25260751
|
MAP4K4
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9712898
8824585
23331499
|
MAP3K1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12228228
9405400
25241761
10465784
15757900
15299005
14500727
21152872
26538579
|
MAPK10
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9393873
16713569
14699954
|
MAPK10
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16648474
10978313
10652349
11274345
|
MAPK10
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12351702
18337589
9482836
9199329
|
MAPK10
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16648474
10978313
17570479
11274345
|
MAPK11
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15187187
17145710
19436832
15140942
10212189
20506250
21614932
16393692
17254968
11274345
|
MAPK14
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
25847991
12351702
28582465
31974640
20047289
22911818
19841061
12000743
15817653
20660302
17570479
22401993
17440046
17185395
24024586
19812390
|
MAPK14
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
21675959
26247731
20213747
17535811
20506250
15657900
9315650
15642743
19413330
11283254
22975381
10581258
16083285
1088347
21614932
16393692
10884347
21050851
16552184
10747897
15187187
17906639
25789565
15140942
11258706
24818748
19436832
10781582
10212189
17172861
10348343
11078726
11274345
|
MAPK14
|
PTPN7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
10559944
10206983
10415025
18088087
16226275
16189514
|
MAPK14
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12842894
15128824
15485852
10521409
15489227
15849198
15212693
12767944
|
MAPK14
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
15649893
20516082
16648474
12944472
11997522
10788511
15304486
10747897
17255949
10652349
11274345
12697810
|
MAPK14
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15649893
20516082
16648474
15121840
12944472
10788511
11030334
10747897
17255949
11274345
12697810
|
TP53
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22607268
23376463
18374905
15958553
10854211
22353755
|
MAPK8
|
NFATC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
14517246
16648474
10978313
23047924
9374467
9630228
11274345
|
MAPK8
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12351702
18337589
9482836
9199329
18669648
|
MAPK8
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
11108663
12531896
16713569
11283254
10706102
19651615
27147566
9724739
15538975
9732264
10581258
10436023
17570479
9393873
11896587
12514174
15580310
18813780
11078726
|
MAPK8
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15743762
14517246
16648474
10978313
17570479
11274345
|
MAPK9
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
14517246
15184502
16648474
10978313
17570479
15958558
11274345
|
MAPK9
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
12356735
14665630
26158765
18778462
12969974
12861053
15254178
17135248
18669630
12384533
17363488
17698850
11283254
10706102
21454683
18931691
11551930
11397945
14612532
15064747
15963507
11175334
11423984
27147566
29234486
24657168
10581258
14517211
17353187
10673500
22030623
14527925
22728651
17525747
15629715
9393873
11447225
15671037
22285752
17245430
15140942
28673515
23871434
11078726
20041275
11896587
16731759
17121812
33514736
11861384
25431954
12810724
17967874
12955074
21832239
16818520
12756247
23798621
11526498
20009884
16713569
10202145
11850826
11896572
10710310
10570149
12959929
15269203
11583595
21148320
|
MAPK9
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12351702
18337589
9482836
9199329
|
MAPK9
|
NFATC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
14517246
16648474
10978313
23047924
9374467
9630228
11274345
|
NFATC1
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21515435
16909108
11423565
21871017
19748606
|
NFATC1
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19915002
18078995
15657420
18299389
16455648
11402342
11030334
|
NFATC2
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23105117
18006811
21871017
|
NFATC3
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21642596
21871017
24291639
|
NFKB1
|
STAT5A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12208876
21725609
23178297
23572150
|
NR3C1
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
8639160
17016446
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
NFKB1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18184402
17673602
16684540
15517885
12160329
15856023
18056465
20538607
17407600
20103608
|
NFKB1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10348347
11032029
8051093
12145335
20097177
|
NFKB1
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
9266823
20669087
12471036
17673602
10827178
16210649
12466023
15517885
12622742
18294142
19618291
12067569
15655349
17556653
9988750
18973191
14988266
12871860
20103608
15555528
11082190
15234907
22001128
16820889
19766095
15997464
12349897
15387324
15368354
18057724
15547942
16624933
17767925
|
NFKB1
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
20966071
22708120
16317091
16271621
10833420
10496926
16249517
7536741
19281832
10553096
19422386
7537851
16385502
10946302
16453001
10329958
11359843
|
NFKB1
|
TRAF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19343319
17673602
14991743
17018379
9733827
9733516
10823821
11297551
|
NFKB1
|
TRAF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15723831
15041463
19392652
18990758
|
NR3C1
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16713569
8290595
16380507
7823959
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
NR3C1
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10631313
18945810
10827178
18657608
9918831
19797430
10701683
18650268
16198345
|
RELA
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23871663
10995388
7659084
8290595
16713569
|
NR3C1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23871663
10995388
7659084
8290595
16713569
|
STAT5A
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9551919
21617857
10433370
16585602
|
RELA
|
PTGS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
16001969
9266823
19783677
12471036
17673602
10827178
16210649
20669087
12466023
15517885
15013753
12622742
20600530
14645117
18294142
19618291
12067569
15655349
17556653
18973191
14988266
12871860
20103608
19284764
15555528
21149600
11082190
15234907
9041934
22001128
16820889
18752821
19766095
15997464
8995303
9710122
12349897
15387324
15368354
18057724
15547942
16624933
17767925
|
TP53
|
PTGS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21187340
16713569
11687965
21763744
|
RELA
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18269916
10348347
11032029
8051093
20061391
15155458
21332394
9890939
21887328
|
RELA
|
TRAF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19343319
17673602
14991743
19383900
17018379
9733827
9733516
10823821
11297551
|
RELA
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18184402
17673602
16684540
15517885
12160329
15856023
18056465
20538607
17407600
20103608
|
RELA
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10833420
20966071
16317091
7536741
16627481
16385502
10946302
19422386
22708120
23042817
19281832
10553096
10329958
11359843
7692229
16249517
10496926
7537851
16453001
|
RELA
|
TRAF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15041463
19392652
21573233
15723831
9733516
|
TP53
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
8108142
20639906
9377555
21325822
16684540
9833779
10910082
16835303
23449391
8521408
15860260
11971180
11559575
|
TRAF2
|
TRAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
10820262
10925299
11112697
11274345
11280761
11438547
11460167
11875494
12433365
12646658
12811837
1431106
14607933
14625680
14660645
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18345002
18633355
18641653
19392652
19411070
20038811
20184663
20435894
21133840
21232017
21411734
21826665
22955274
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
8910423
|
TRAF2
|
TRAF1
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
10820262
10925299
11112697
11274345
11280761
11438547
11460167
11875494
12433365
12646658
12811837
1431106
14607933
14625680
14660645
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18345002
18633355
18641653
19392652
19411070
20038811
20184663
20435894
21133840
21232017
21411734
21826665
22955274
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
8910423
|
TRAF2
|
TRAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
49.0
|
1.0
|
ACSN
|
10820262
10925299
11112697
11274345
11280761
11438547
11460167
11875494
12433365
12646658
12811837
1431106
14607933
14625680
14660645
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18345002
18633355
18641653
19392652
19411070
20038811
20184663
20435894
21133840
21232017
21411734
21826665
22955274
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
8910423
|
TRAF2
|
TRAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
8702708
15383523
16713569
8069916
21903422
25996949
9500555
14743216
11181075
15323523
25241761
14557256
20385093
32296183
10544141
12887920
19287455
8548810
9718306
31515488
29748372
|
TRAF1
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
8702708
15383523
16713569
8069916
21903422
25996949
9500555
14743216
11181075
15323523
25241761
14557256
20385093
32296183
10544141
12887920
19287455
8548810
9718306
31515488
29748372
|