Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MDM2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19816404 21986495
ATM EYA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19234442 19351884
SP1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15837784 11466608
FOXO1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15059979 10871843
PAX3 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10871843
FUS BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
RARA CCNH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0509717103 16769902
GTF2F2 CDK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17690249 22492511
GTF2F1 CDK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17690249 22492511
CDK9 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
NUPR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22858377 18690848
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
PPARG CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15041706
CDKN1A POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678112
CDKN1B CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
PPARG CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11034103 15763423
TAF1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18684994
KMT2A CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997566
COPS6 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 MNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DDIT3 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19359519
TARDBP DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DDX5 GTF2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
DDX5 GTF2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
DDX5 HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16917507 5218981
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 CCNT1 â—¼   ACETYLATION ✅ 2.0 0.8 intact 7265510 19387490
EP300 DDX17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20663877
EP300 H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
GTF2H3 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8652557 10734072
POLR2C ERCC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
GTF2H4 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9118947 10734072
SIX1 EYA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12783782 20110314
FOXO1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16670091 19289458
FOXO1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20338229 15632117
POLR2C GTF2H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
GTF2H2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10949034
TARDBP HNRNPDL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RALY HNRNPDL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CEBPB KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23456364 17301242
TAF1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17085686 9285713
H3-3B KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
H3C2 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
H3C14 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KAT2B H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 34811519 15616580
IGFBP3 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYCN KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
KAT5 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 GADD45G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KAT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10096020
FLI1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592502 20153576
DDX17 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17226766
TARDBP MNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H3-4 POLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17099721
RNF113A ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SAFB FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
SAFB ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10707955
TAF5 TAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 362175 7680771
TAF1 TAF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22711989 16407123
TBP TAF12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219590 17268553
TBP TAF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20189987 15637059
TAF7 CCNT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0801637105 18391197
TBP TAF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22711989 24082143
H3C14 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16774833
H3-4 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16774833
RUNX1 HHEX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28213513
KMT2A CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997566
POLR2C DHX15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
CEBPB GADD45G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11012671
NFKB1 GADD45G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23681230
TARDBP HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SF1 HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPH1 RALY â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPH1 REL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
JUP BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCNT1 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CCNT2 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
ETV6 MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11439334 10913166
ETV6 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17606295 19829305
ILF3 SNRPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPUL1 SNRPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
TARDBP ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYCN ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12670915
RARA PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10361124
PLAU PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721771 16189514
NFKBIZ IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15241416 26226212
PTK2 ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16874740 10592173
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
HDAC1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16431920
BCL11B HDAC1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
PPARG HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21151932 16431920
HDAC2 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
RUNX1T1 NCOR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18952841 0802696105
ESR2 NCOR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816459 22622808
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
PPARG CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15741503 17237441
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
SPI1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18227805 12393465
CEBPA CD14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 IL2RB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15084276 18003603
SP1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199305
SPI1 CEBPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8695841 22474248
SPI1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22105598 12032776
SPI1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24503536 19423615
SPI1 CSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SPI1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689920
SPI1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8264604
CEBPB CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7513199 21455770
CEBPA IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10453008
RUNX1 IL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9036972
DROSHA SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SP1 GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12972613 22265959
SP1 PAX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 18314536
SP1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10373535 12049196
DDX3X SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16818630 33627125
CEBPA IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7708053
ESR2 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24914937 11457856
RARA IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14715249 9153223
EWSR1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21531709 15282325
RUNX1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19686049
NFKB1 NFKBIZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20220144
NFKB1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21790895
NFKB1 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9294162 9733516
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
ESR1 MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22927007 24374826
CEBPB MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21917825 19723873
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
CEBPA RUNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17431401 5219852
RUNX1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18316480 26010396
KMT2A RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23817177 22012064
RUNX1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17431401
RUNX1 MPO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPA ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPA CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPA MPO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
MET PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521801 16782899
ESR1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11060032 21610700
CCNT1 GTF2F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17690249 22492511
KMT2A HOXA10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15941828
KMT2A MEIS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16199523
KMT2A HOXA11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15941828
H3-4 HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPU TAF15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SF1 HNRNPUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPUL1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 GTF2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
ESR1 GTF2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
ESR1 GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841876 16651265
TBP GTF2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
TBP FUS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19841068
TBP GTF2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7521915 16330756
RXRG RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ESR2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
RARA ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
GTF2F2 POLR2E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11278533
POLR2C GTF2F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2C GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
GTF2F1 GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218897 16878124
TARDBP DDX3X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SF1 ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
POLR2C GTF2F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
PAX5 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21549805 16482219
PAX5 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15676205
DDX1 RTRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRMT1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TARDBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLR2C POLR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
TAF13 TAF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6548076 9695952
DDX17 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EWSR1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16206264 10975680
FLI1 EWSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16206264 10975680
PAX7 PAX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18513381 17954266
H3-4 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-3B H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
DDX17 DHX15 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
CCNH POLR2C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CDK7 GTF2F2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CDK7 GTF2A1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2F2 GTF2H1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2A1 GTF2H2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2B GTF2H2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2H2 POLR2C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2A1 TAF7 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
DDX17 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17226766 19995069 33742100 20663877
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 PAX5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31941781 21357426
TAF13 TAF6 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17643375
PPARG SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18509005 24735796 20360975 22282354 18310298
HNRNPA1 HNRNPM â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
DROSHA SRPK1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CDK7 POLR2C â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DDB2 HIST2H4A â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
GTF2H2 POLR2A â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
GTF2H3 TBP â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CDK9 PLEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 26209609
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
CUL4A DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 32235678
GTF2B GTF2H3 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
GTF2F2 GTF2H3 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
GTF2H3 POLR2A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
SP1 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16050810 15647279
KAT5 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27295567 16169070
TAF6 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14580349 23292512 22939629 26344197
ESR1 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
CUL4A NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30945288
BMI1 NCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ETV6 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12527908 11439334
BMI1 ILF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
MYCN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYCN HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31856871 20697349
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
PPARG RARA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
NEDD8 DDX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
NEDD8 DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
BMI1 PLEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 ILF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 RALY â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
AFF1 CCNT1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
ESR1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 21182205 19805454 20348541
DGCR8 RALY â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RXRG RXRA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GTF2F2 GTF2H2 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST2H4A SOX2 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
GTF2A1L GTF2A2 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
HIST2H4A KMT2A â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
SRPK1 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
CDK9 DDX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17643375 26209609
CDK9 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11689688 12861003
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
NUPR1 FUS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19650074 16478804 32780723
TAF10 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 7923369 31527615
TAF4 SP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11988536 9742090
TAF6 TAF9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23292512 7597030
ILF2 RALY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SOX2 KDM6A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 22801502
NCOR1 ESR2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29509190 12904255
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
FUS RALY â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30354839 29884807
HIST2H4A TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
FLI1 RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
FUS PRMT1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
KAT5 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDX3X FUS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CDKN1B CUL4A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DDX5 DHX15 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SRPK1 DDX5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
ETV4 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9194565 14976201 35140242
EP300 ILF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20808282 33742100
SUPT3H TAF5 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
TAF11 TAF6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14580349 29111974
TAF11 TAF7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14580349 29111974
DHX15 FUS â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
NCOR1 ETV6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11001911 11439334
FUS ILF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27460707 29884807
CEBPA HDAC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15713621 22355045 23898169
CEBPB SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16651265 12847250 12665574
ESR1 IGF1R â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10749889 24051437 14764897 28555617 16113100
ESR1 RXRA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9717844 23403292 9121466
DGCR8 DDX17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24581491 17765891
DROSHA FUS â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
HNRNPH1 SNRPC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HOXA9 KMT2A â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DOT1L HIST2H4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST2H2AC HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GTF2A2 TAF1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
GTF2F1 GTF2H1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CDK9 CCNT2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B SIN3A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 34026424 25189618
RUNX1 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14752096 16917507
ILF2 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
PAX8 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10924503 35140242
TAF11 TAF10 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14580349 29111974 23292512
TAF12 TAF7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14580349 33961781 29111974
TAF4 TAF7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14580349 29111974 22939629 26344197
SPI1 TBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11593411 8434021
MYCN SP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18003922 21123453 20697349
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
TBP REL â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8413269 16713569
FUS DDX17 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807 26344197
CEBPB RUNX1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HNRNPU PRMT8 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
GTF2H5 TBP â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
DDB2 HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
GTF2E1 GTF2E2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
ESR1 CCNH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12527756 31527615
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL4B DDX5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
EP300 FOXO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15890677 24419059 25609649 18786403 11896584
PER2 MDM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34257372 25103245 30425162
MDM2 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20708156 24804778
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
TAF13 TAF4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 17643375
CUL3 DHX15 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26949739
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
CUL1 DDX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 21145461
SPI1 CEBPA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16983342 12091339
ESR1 CCNT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15940264 31527615
ESR1 RARA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9717844 25303530 25604459
ESR2 PLEC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25604459 21951318
GTF2H1 POLR2C â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
GTF2A1 GTF2H5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
GTF2H5 POLR2A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
GTF2A1 TAF1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
GTF2A2 TAF4 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
NCOR1 BCL6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15454082 16713569 9824158 11865059 10898795 16147992
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
TBP MDM2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9388200 16713569 9271120
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
HDAC2 GTF2I â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12393887 30737378 12493763
SOX2 NCOR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 28794006 23667531
CUL3 ARMC5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 33130828
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
RXRA FUS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32814053 9440806 16713569
CDK9 MLLT3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS6 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NCOR1 RUNX1T1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
IGF1 IGFBP3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AFF1 MLLT3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ERCC3 GTF2A1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2A1 GTF2H4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2A1 MNAT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MNAT1 TBP â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
POLR2G TBP â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2A1 GTF2F2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2A1 POLR2A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2A1 POLR2C â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2A1 POLR2G â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF1 CDK9 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED26 POLR2E â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
DDX17 SF1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HDAC1 RUNX1T1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
KAT2B RARA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9445475 17475621 14581481
IGF1R MDM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 12821780 20195357 28092675 18632619 19165858
TAF10 TAF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29111974 7923369 17643375 23292512 14580349
TAF12 TAF9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23292512
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
HDAC2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17312152 18059533 16713569 15713621 17894944 12091390 16036112 12151407 21159880 12176973 20697349
SP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18083845 16740634 33572115 7933095
CEBPB CEBPA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20102225 1840554 15751966
TBP RXRA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 7667283
RARA RXRG â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IGF1R MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDKN1B COPS5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
GTF2F1 GTF2H3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PRMT1 PRMT8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CCND2 CDKN1B â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC1 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15454082 9627120 9753732 16147992 10611298
AFF1 CDK9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32707033 32479599 20153263 33961781 21729782 21030982 23602568 26186194 27684187 23455922 24367103
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
CEBPA DDIT3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 27555288 23661758 20102225
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
FOXO1 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22266855 11435445 11353774
KAT2B TAF12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 9674425 24981860
TAF1 MDM2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9388200 17237821 16713569
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
TAF13 TAF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29111974 17643375 31753913
TAF10 TAF7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29111974 22939629 15099517 17643375 9603525 23292512 14580349
TAF5 TAF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14580349 23292512 11406595 26344197
GTF2A1 TAF6 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
DDX17 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15298701 19995069 20663877
HDAC1 SPI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 16331260 11593411
SPI1 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 9478924
RARA SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18270252 10361124 19401466 16713569
SP1 RXRA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18270252 10361124 10393239 16713569
HIST1H3A KMT2A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
AFF1 CCNT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20153263 21030982 27684187 19956800 24367103
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
ILF3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 29884807 16713569 11438536
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
GTF2A1 GTF2F1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
COPS5 DDB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ERCC2 TBP â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
ERCC2 GTF2A1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
GTF2A1 POLR2E â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
DOT1L MLLT3 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
CEBPB BCL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19489038 18512730 12665576
CEBPB BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19043455
SIN3A BCL6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16147992 9765306 9753732
BCL6 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21106671 12594267 15507530
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
CCNH ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 33707221 17643375 15220921 33453189 8692842 33961781 26186194 19934020 9118947 26340423 10734143
CCNH GTF2H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19172752 26340423 10734072
CDK7 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 8692841 17643375 15220921 8521393 33453189 33961781 10082552 9130708 23602568 28977422 32707033 29568061 26340423
COPS6 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KAT5 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17671089 20351180 16601686
EWSR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12560328 18757425 20153576
TAF1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17996705 14993269 24289924
RUNX1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10617663 23487742 23150456
ESR2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19487281 14729654 23907131
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
KMT2A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16169901 19318494 19031738
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
CUL4A DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 28514442 22118460 28035050 11564859 21145461 29262658 16473935 15811626 18593899 26496610 30923324 16964240 20368362 19295130 16751180 33759138 16260596 27203177 17609381 32985517 10585395 17041588 31973889 12732143 33961781 26186194 17626091 30945288 16949367
CEBPB DDIT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12706815 20562859 33961781 20102225 1547942 8662954
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
DDX5 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14631847 28539435 14675539
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
DDX5 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 20308691 11250900 21182205 10409727
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 CEBPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28428115 9343424 14630807 12471036
EP300 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 17468099 10944516 14701856 11287611 19596656 32603375 11877444 12040021 10075656 30595551 22787115 12479814
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
GTF2H3 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9118947 8652557 10734072
FOXO1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21471200 21281751 20650891
FOXO1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12391153 15613482
HOXA10 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12493691 18391971
GTF2H3 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8652557 15790571 10734072
KAT2B MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21209460 21060154 32404984 14769800 12068014 28286521
KAT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34811519 16096646
ESR1 KAT5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 17418098 16260778 22081016 11591700
KAT5 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18499675 11927554 18264029 19150978
MDM2 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11927554 16904321
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
TAF1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 10891494
TAF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 16713569
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
SAFB MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TAF4 TAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29111974 22939629 14580349 31753913 11564872 26344197
TAF7 TAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29111974 22939629 16713569 7824954 31753913 11592977 18391197 14580349
TAF12 TAF10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19114550 9603525 23292512 33961781 24981860 12601814 14580349 7729427
TAF10 TAF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22939629 17643375 11406595 19114550 9603525 23292512 12601814 14580349 26344197
TBP TAF10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16945932 18722179 12020826
TAF12 TAF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14580349 23292512 33961781 10594036 15601843 11564872 12237304
TBP TAF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8858156 19240132 9603525 10373431 9674425 9153318 22323595 22939629 17967894 12665565 9311784
MAP1LC3B TAF7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TBP TAF7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29111974 17158164 19240132 9603525 22323595 9153318 12665565 9311784
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SNRPC EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10827180 16713569
NFKB1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11689575 17407600 20352621
ESR1 ITGB7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15647279 20072153 19062177 11909966 17894944 21636851 18003922 12176973 11896613 15557281 10409740 11517158 15713621 12665570 15722551 17906119 16478997 18850004 16121030 16883603 12091390 15155736 18948152 18059533 16713569 20385359 15528196 16734381 12200149 12847090
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
NCOR1 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11903058 17468099 10339548 30575522 15681609 15604093 19596656 22078880 35140242 11877444 16127449 30595551 23703729 21775429
NCOR1 RARA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9531570 19377461 10336495 16606617 25303530 21988832 27107012 9121466 10882117 15604093 16469706 30532072 18978041 15336696 7566114 9486655 20543827
NCOR1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 24051437 12145334 16469706 17400812 12738788 21182203
NCOR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22395773 20462215
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
PPARG RXRA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22363753 16189514 12763030 10944516 31547433 30404011 20211142 35140242 25609649 17312272 23703729 7838715 19047629 12966085 22205725 14587029 10882139 30595551 30699358 9065481 21833030 9568716 34081964 21478865 9121466 23275339 17579352 19147680 26260846 16713569 12591919 10854698 30651555 32929351 23711995 11877444 15888456 18217139 19043829 17980149
PPARG IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18394717 20064783 20685873
PAX5 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10688639 11179673 21549805
SP1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7811231 8524292 11418664
CEBPB IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12574125 10453008
SP1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8454603 23226269
ESR1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
SP1 NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19656944 19643914 21123453
IGF1R IGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26027733 21645859 8452530
FLI1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21531709 15282325
NFKB1 REL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 27609421 17962807 35140242 33961781 25609649 26186194 15143182
NFKB1 BIRC2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
NFKB1 MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11376631 19275880
TBP MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9203586 8058785 10672904
REL BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9372964 12414938 10049645
RUNX1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22451420 11283671 17894555
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
CEBPB RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17579210 21302301 21612856
CEBPB RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15713650 11668178
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 DDX17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 11250900 21182205 20348541
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
ESR1 HOXA10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17311863
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
TBP PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14631847 28539435 14675539
TAF11 TBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10591645 29111974 17375202 8670810 19240132 9603525 9153318 17967894 7729427
GTF2A1 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14631847 28539435 14675539
SRPK1 DGCR8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 23602568
SF1 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9660765 16713569
ESR2 PDGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR2 HOXA10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17311863
ESR2 PBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
GTF2A2 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14631847 28539435 14675539
PRMT1 TAF15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19124016 15782174
RXRA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19538480
PAX3 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8633043 20067553
SOX2 PROM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22937156 21947321 23326489
HOXA11 HOXA10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17688409
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
GTF2A1 GTF2E1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DDX17 FUS â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ERCC3 GTF2F1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2A2 GTF2H5 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2F2 GTF2H5 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2F1 GTF2H5 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2B GTF2H5 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2G â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2E â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2C â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2F1 MNAT1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2A2 GTF2F1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ERCC3 POLR2G â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 GTF2A2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2A2 GTF2E2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2E2 POLR2G â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2F2 GTF2H4 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2A2 GTF2H4 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2C â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2E â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2A2 MNAT1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2B MNAT1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2F2 MNAT1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2E â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2G â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2C â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2A2 GTF2F2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2A2 POLR2C â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2A2 POLR2G â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
DDX17 DROSHA â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CCND2 CDKN1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HNRNPA1 HNRNPH1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HOXA9 PBX1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
NFKB1 REL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ILF2 ILF3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
TAF11 TAF5 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 14580349 29111974 9045704
TAF6 TAF7 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 14580349 29111974 22939629
MEIS1 PBX1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CDK9 POLR2A â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ERCC2 GTF2A2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2C â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 GTF2F2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2E â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 GTF2B â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2G â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
GTF2A2 GTF2E1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
POLR2C TBP â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
GTF2A2 POLR2E â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
POLR2E TBP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NCBP1 SNRPC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
GTF2F1 GTF2H4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ERCC3 POLR2C â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
GTF2B GTF2H4 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
GTF2H4 POLR2A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
GTF2H4 TBP â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
TAF12 TAF11 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 14580349 33961781 29111974 7729427
GTF2F2 TBP â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
GTF2A1 GTF2E2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
GTF2E2 TBP â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GTF2H1 POLR2A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
MED26 POLR2G â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ERCC3 TBP â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HIST1H3A MLLT3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
SUPT3H TAF6 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
CDK7 GTF2H5 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
GTF2E2 POLR2C â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
GTF2E1 POLR2G â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
GTF2E1 POLR2C â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CDK7 GTF2H4 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CCNH POLR2A â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
EYA1 SIX1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
TAF10 KAT2B â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 17643375 31753913 19114550 10373431 24981860 9674425
TAF5 TAF9 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 23292512 17355863
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
DROSHA DGCR8 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 22222205 8308421
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
GTF2A1 GTF2B â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ERCC3 GTF2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
GTF2H4 POLR2G â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ERCC2 GTF2F1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
GTF2B GTF2E1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CDKN1A CCND2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 16765349 5218735
GTF2B GTF2E2 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
TAF10 TAF6 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22939629 17375202 15099517 19114550 9603525 23292512 12601814 14580349 26344197
TAF10 TAF5 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22939629 17375202 19114550 9603525 23292512 12601814 14580349
TAF13 TAF5 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22939629 17643375
TAF5 TAF7 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 14580349 22939629 29111974 9045704
NCOR1 SIN3A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17210713 11430826 16713569
GTF2F1 TBP â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
MNAT1 POLR2A â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
GTF2B POLR2C â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
GTF2A2 POLR2A â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
KAT2B TAF10 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
KAT2B SUPT3H â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
DDX5 DROSHA â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
GTF2E2 GTF2H3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
GTF2E1 GTF2H3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
GTF2E1 MNAT1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
GTF2E2 GTF2H2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GTF2E1 GTF2H2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GTF2E1 TBP â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GTF2A2 GTF2B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
BCL6 NCOR1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CCNH ERCC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33707221 8692842 33961781 26186194 22939629 26340423
CDK7 ERCC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 8692841 33961781 26186194 11445587 23602568 32707033 22939629 29568061
DDX17 DDX5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22365833 15298701 19995069 22863883 33961781 24581491 10837141 22939629
TAF5 TAF1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 29111974 22939629 31753913 7680771 9045704 14580349 26344197
TAF10 TAF13 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 23292512 7729427
TAF10 TBP â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7923369 17375202 15099517 19240132 7744009 7680771 9603525 10373431 9674425 9153318 22323595 23292512 22939629 17967894
TAF5 TBP â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17375202 8858156 15870280 17884155 19240132 7744009 7680771 10373431 9603525 9674425 9045704 9153318 22323595 26344197 17967894 9311784
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
GTF2E1 POLR2E â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
ILF3 ILF2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16189514 20808282 23986595 33961781 17389650 26186194 29395067 22939629 26472337 11739746 21969602
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
TAF13 TBP â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 29111974 7729427 19240132
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
ERCC3 GTF2F2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
GTF2H5 MNAT1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
TAF13 TAF5 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
TAF13 TAF6 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
GTF2F1 POLR2G â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
GTF2F1 TAF1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
GTF2E2 GTF2F2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
GTF2E1 GTF2F2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
GTF2E2 GTF2F1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SUPT3H TAF12 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
GTF2B POLR2G â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ERCC3 POLR2A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CDK7 GTF2E2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDK7 CCNH â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9334327 15698475 11113184 15328539 33707221 17643375 8078587 26340423 33476598 8521818 8521393 23602568 29568061 33453189 32707033 22939629 11713533 10958691 8692841 16782892 9218599 33961781 10082552 26186194 9056480 26344197
CDK9 CCNT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9499409 11145967 15328539 17643375 20562857 9491887 20305087 15713662 19387490 11713532 27684187 14627702 23455922 16980611 26659056 15107825 12588988 12944466 14580347 20153263 22959624 16109377 12115727 21729782 23602568 11282025 30649429 19914168 18483487 24367103 20535204 12832472 19818711 12894230 9872325 23064645 30652970 15713661 21697490 22483617 22939629 32707033 11713533 15528190 15546612 10958691 10617616 10574912 18566585 10465067 24981860 33961781 11689688 17700062 26186194 26344197
CDK9 CCNT2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32707033 9499409 16331689 18566585 17643375 10465067 33961781 24981860 21729782 26186194 23602568 11282025 27684187 23455922 11713533 26344197
ERCC3 ERCC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15220921 9118947 8652557 19934020 16669699 33381997 8152490 22939629 22678362 26340423 27193682
TAF12 TBP â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17158164 19240132 7729427 9603525 33961781 9674425 17967894 17268553 8663456
TAF12 TAF6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14580349 9133630 23292512 33961781
TAF12 TAF5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14580349 33961781 23292512 9045704
TAF5 TBP â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
RARA RXRA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 9415406 25241761 21988832 16540467 15604093 1310351 10698945 14521715 12052862 9582446 19345331 31700049 7760852 15528208 21478865 9121466 10882070 16769902 15171703 22539306 25303530 7705655 16713569 1314167 16224062
IGF1 IGF1R â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
GTF2H2 GTF2H5 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GTF2H1 GTF2H5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GTF2E1 POLR2A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NCOR1 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ERCC2 GTF2H5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ERCC3 POLR2E â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GTF2E1 GTF2F1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6613869 18483487
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CDK7 GTF2H2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
GTF2E2 GTF2H5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
GTF2E1 GTF2H5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
HIST1H3A KAT2B â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NCOR1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
POLR2A TBP â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
GTF2B GTF2F2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK7 GTF2E1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
GTF2E2 POLR2A â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
GTF2E2 GTF2H4 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CCNH GTF2E1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
TAF12 TAF13 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
GTF2E2 MNAT1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ERCC2 GTF2E1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ERCC2 GTF2E2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SUPT3H TAF10 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CCNH GTF2E2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
GTF2E2 POLR2E â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
GTF2E2 GTF2H1 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
TAF6 TAF1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 29111974 22939629 7667268 31753913 12453419 14580349 26344197
TAF5 TAF6 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 22939629 10523658 23292512 17355863 9045704 14580349 26344197
TBP TAF6 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 17375202 8858156 15870280 19240132 7680771 9603525 22323595 9674425 9153318 12453419 22939629 17967894 12665565 9311784
GTF2F1 POLR2E â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
GTF2F1 POLR2C â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
TAF11 TAF13 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 29111974 9695952 7729427
PBX1 MEIS1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 20237320 20211142 10082572 20541704 10523646 10373562
CDK7 GTF2H3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
GTF2F2 POLR2C â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
GTF2E1 GTF2H4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ERCC2 GTF2H4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ERCC3 GTF2E2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ERCC3 GTF2E1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
TAF13 TAF4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GTF2B POLR2E â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GTF2F1 POLR2A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDK7 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
GTF2B GTF2F1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
DGCR8 DROSHA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCNT2 CDK9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TAF12 TBP â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TAF4 TBP â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GTF2A1 GTF2A2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDK7 ERCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ERCC2 GTF2H3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2H3 GTF2H5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TAF4 TAF5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TAF6 TBP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2B TBP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2F2 POLR2G â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2B POLR2A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCNH GTF2H3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2E1 GTF2H1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2H3 MNAT1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2H4 MNAT1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TAF10 TAF5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TAF13 TAF7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2F2 POLR2E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2F2 POLR2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCNH GTF2H5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH ERCC3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH ERCC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 MNAT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 MNAT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H3 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H4 GTF2H5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF1 TAF5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF10 TAF11 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF10 TAF13 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF10 TAF12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF11 TAF12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF12 TAF5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF11 TAF5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF5 TAF7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2F1 GTF2F2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF11 TAF13 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATM H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM MDM2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23148884 18619531 22826432 27156884 29144413 29294106 23046908 17609267 18171990
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 66.0 1.0 Omnipath 14654783 12383858 17936559 20651945 17303408 19816404 10611322 23150762 23277204 23386996 26416444 27258263 23002429 11331603 15865937 21556066 16163361 23708100 17570479 20514355 22264782 27177180 18265945 28690977 23847781 22264786 15140942 15964794 19788416 22624716 25201202 27462439 12607003 28050229 32350255 22649771 27956626 15459660 22976441 25247188 28904407 11877377 21859827 24534650 23405218 29290977 27568562
NFKB1 BCL2A1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10049356 21725609 23178297 23572150
NFKB1 BCL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19343319 12665576 17000776 11880364 15592513 10733571
NFKB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10925251 17673602 12176906 11992002 14978135 15231833 14739605 10585435 20066113 16904634 9439816 18222423 10733571 15756023 15986355 12226754 15856023 16453001 11756417 18223231
NFKB1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10428780 19211554 10435632 10428030 11756417
SPI1 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19564417 15892171 31000603
BCL6 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19337254 18648506 15509806 22723377 17392284
NCOR1 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15454082 16147992 9824158 16713569 10898795 11865059
CCNH GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH CDK7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH MNAT1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDKN1B CCNH â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDKN1A CCNH â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCND2 CCNH â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCNH CDK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23602568 11113184 8521818 16782892 15698475 15328539 19153657 10082552 26340423 8692841 26186194 9334327 10958691 10734072 9056480 9218599 8078587 8521393 17643375
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 MNAT1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 MNAT1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDKN1B CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDKN1A CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCND2 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23637584 15670742 15249124 33902658 22135230 12054865 19917671 30532072 11955452 19078967 16713569 21297158 16769902 9230306
CDK7 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18079403 27197304 26799765 10886368 14662762 16327805 24662513 26748711 25561469 21331744 19667075 18079404 22137580 9130709 20457598 19901026 19450536 20932174
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK9 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 22053051 20222012 25023704 14662762 10364292 20106982 18066052 30135578 24385927 18644870 18329373 14517250 20932174 12052871 20226668 19575011 8416977 11575923 16735508
CDKN1A MNAT1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
NCOR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22253232 20466759 20696891 24821728 24821727
TBP CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15280358 17130157 17996705
CEBPA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15466360 9442037 12502863 8846917
ID2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17639499 16557594 21900881 16428453 11706002
RUNX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21913213 17438369 19179305 15107836 12391164
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
FOXO1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17609436 23574718 23918930 24769335
RARA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10356361 24821728 21383775
CEBPB CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10982390 15466360 15041706
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
PPARG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19551868 19103521 19208833 16985067 18509005 15041706 15345676 16091736
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
FOXO1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15084259 19380174 21708191 15084260 21613825 17940099 11154281
CDKN1A CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23443559 26186194 25241761 27107012 8756624 15169570 25416956 16765349 31515488 16189514 32296183
CDKN1B MNAT1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
SP1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9349726 12907235 18355800 10072762 19145069 21131823 22415074 15064717 15951157 16105842 23184467 15899840 12773549 12907249 10542271 16518840 11231912 19433067
FOXO1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21418583 17015685 12359217 12391153 11094066 18593906 19281796 18787071 23160481
FOXO1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11073996 19380174 10783894 20673124 11094066 15668399 17646672 21708191 15084260 21613825 17940099 11994454 11154281
COPS5 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 22350412 15688030 18926707 24671224 12082530 18202760
CUL1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15340381 15147722 12820959 12835716 11961546 11516665 15071497 15688063
CDKN1B CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25910212 16189514
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CEBPB DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8051100 16757577 10085237 8662954
DDIT3 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7588595 21983012 11050169
DDIT3 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18772138 22031759 17709599 15688424 21471847 18850010 17197543 15659384
MAPK13 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 11274345
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
LYL1 EP300 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18160048 21486943 15620361 11840323 27128622
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
ERCC2 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 MNAT1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H1 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9130708 8652557 10734072
ERCC2 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10734072 8652557 10024882 16669699
ERCC2 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12820975 10734072 9771713 8652557 16189514 19934020
ERCC3 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2F2 ERCC3 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2A2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2E2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2E1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2A1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2B â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
TBP ERCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7521915 11089979 22848139 9400991 8087622
GTF2H1 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10403766 10734072 9173976 8194528 15220921 9118947 9130708 8652557 11259578 26340423 17643375
ERCC3 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9118947 8652557 16189514 10734072
EYA1 SIX1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 15492887 28514442 32296183 11734542 12874121 33961781 26186194 15226428
SIX1 EYA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17035528 15226428 15492887 11734542 32296183 12874121
CUL1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080
CEBPB FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18391971 11893744
ESR1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17145710 18391971 22266855 11435445 11353774
FOXO1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16670091 12966085 17317207
GTF2H1 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H1 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21988832 10734072 11062469 9130708 8652557 8194529
GTF2H2 GTF2H4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H2 GTF2H3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H2 MNAT1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SP1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20130956 20144149 17882273 15647279
H3-4 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
MYCN MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15917661 15644444 15927364 19649205
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
MDM2 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 25241761 28092675 12821780 18632619 17303558 19165858 36042202 20195357
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
SP1 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21611785 22890831 22125028 20963645
CCND2 MNAT1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
MNAT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10428798 10949034 12527756 16076840 8308015
TAF1 TAF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF11 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF12 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF10 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF13 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TBP TAF1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 29111974 17375202 31753913 7680771 17967894 9311784 9858607 9674425 9153318 15870300 8995708 7597030 15564746 9603525 18391197 9660973 16713569 8858156 17884155 19240132
TAF1 TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16858867 11316804 9699517 15808844
TAF1 GTF2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17081983 11278496 18452278
TAF1 GTF2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 8625415 7590250 9660973 10428810
TAF10 TAF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF10 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF10 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF10 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF12 TAF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF12 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF12 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF11 TAF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF4 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF4 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF5 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF11 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF6 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF11 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF7 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SP1 TAF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12364593 11340078
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
SP1 CDKN2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18642058 15107822 22504641 12077144
KMT2A HOXA9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 15941828
HOXA9 MEIS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10082572 15161102 9343407
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
KDM6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24561908 17713478 20123895
PLAU PTK2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
SP1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23978400 10361124 21567400 21076612
ETV4 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1330539 8570190 9295342 11676474 8761947 7760840
CD14 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IL6 CEBPB â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
REL IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17513725 17982049 11564778 11160296 1372388 19122653 12426000 9171095 8910763 16688168
SPI1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15013752 23509362 18680724 19502584 25567680
CEBPA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15158360 10748205 11975924
CEBPB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 8441418 10748205 21069809 1327803 7543095 11004486 9312180 23595969 15389813 12853840 7651415 7744000 9523851 19026986 17332680 8786324 8910763 11250916 23361365 11114305 7821611 21127061 9516466 10816606 1730090 8234276 15044620 9282937 16784777 20511231 1427600 24472318 7818522 10903137 23874122 8336793 22558159 14600152 19632992 9661072 14530280 1421375 11160296 9182853 22895549 25382637 9378980 9648065 24012417 11866474 8725624 12177065 8752656 11035101 18955501 2112087 15613028 9442386 9199508 7744784 15688424 8346247 22074460 17955490 12706815 11594800 11120852 10435001 8325885 19782405
NFKB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 71.0 1.0 Omnipath 17513725 18061164 12058956 24337575 19124729 15611045 11058167 9523851 15517885 12887736 15158360 7876168 17495236 25549935 17982049 15241416 18243142 9516466 2405250 18996370 8824277 18310089 24664372 15749903 10903137 16112536 14532843 11327783 18942706 11975924 20066113 16984731 10975857 11160296 19703987 22895549 10963848 10469356 22547075 17040605 11459775 17490702 19469019 8247545 11504280 15756023 10569191 10823821 20696864 12907458 19707556 16043358 11035101 12176740 11302724 8679226 8725624 22578249 8752656 17196927 17532054 12727841 18057724 7499267 10329846 9199307 9502421 19164127 11120852 24676671 11098847
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
PPARG NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15175761 11877444 15604093 16127449 11903058 22078880 23703729 9121466 21775429 17468099
NCOR1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16469706 12738788 12145334 17400812 16713569 21182203
CEBPA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22685373 25119735 8999951 18199703
PPARG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19395102 18485432 20107546 20554962 16303327 20889551 15331599 12695526 15720834
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
NFKB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 9510190 12058956 11973337 18786178 17045242 15289496 16701870 19376732 19837667 9698090 17276517 11512674 19786024 20038977 10202011 15057743 15517885 12643600 11342414 7876168 15350531 18034886 11716760 11564889 11864912 12218154 12707271 10969814 12748173 14631383 16325549 17586662 18996370 19732956 17041011 10530453 18281166 12716652 16418726 12485925 16004996 9388261 8878392 17917246 10975857 10745031 10928981 16553947 16818736 14670967 18435575 12038622 15958549 17040605 8413215 21255844 22340043 1401924 9452482 16764699 11297551 15950427 15387324 15879558 16105834 11953364 15688424 18074095 8413306 11096450 16803583 10506755 11120852 10477716
CEBPB CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23051921 10775602 17135982 8969274 17997161 18512730 21471847 24554449 14645117 15085176 17845418 12707271 12748173 19489038 22031759 8234276 19064995 8207232 16989899 27856305 11991987 19109189 17471497 19786303 16809637 16818736 21255844 19734226 24038085 18772138 19805069 20861254 18487355 11390611 15688424 10462040 16803583 8999951 11120852
REL CUL1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10321728 9990852 10066435 9859996 10514424 10230406
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 USP15 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 USP15 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 USP15 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
CEBPB PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22473998 23934183 7557387 12524424 16431920 22610404 15110775 18694725 17242167 16054042 15158467 9950217 10862621 20829347
CEBPA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22553076 20725087 15664998 15110775 18619497 19059241 9367890 15158467 23071089 10862621 15632071 16580992
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
PPARG RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12878983 18715135 20589837 12704187
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
PPARG RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12615696 16189514 18988627 15130092
CD14 ITGAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10201950 16751103 3537192 2462607
SP1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11698458 17203216 12213324 7512565
RUNX1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23817177 19339695 20972335 24037986 18316480 19208846 17994017 12576332
SP1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12706891 22734486 10446912 7478579
CEBPA SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17671233 24429361 14636649 20972335 12949251 14592841 12032776
SPI1 FCGR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12393465 7869026 8035786 12130529 15304324 14734612 10820245
SPI1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10823830 11481336 14962802 19801646
SPI1 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17116688 8264604 9506963 8302571
SPI1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10523830 9858537 23056458
SPI1 ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9689920 8756629 16247445 9192779 14732495
SPI1 ITGAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8955212 19747912 12393465 19502584 9295016 15163413 8095266 25005557
CEBPA SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10397723 12091339
SPI1 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8095266 15676205
NFKB1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 11418664 12760745 8135780 8934574 14741709 18285351 10608823
REL CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9414129 11418664 8152309 8662666 8934574 8660380 9185524 24899500
IL3 CD86 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
IL3 CD40 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
RUNX1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11997340 9036972 20506188 15735013 10023677 8180380
NEDD8 USP15 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 USP15 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 USP15 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CD40 CD86 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
NFKB1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10586028 15949284 19164127 15895390 18929846
SP1 MPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057865 17521322 8662930
SP1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10720440 21447702 7497000 15345673 17170218 7491107 17049831 17014845 10982795 17486080
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
SP1 PDGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15297375 9453298 9321833 9351401 22964636 7499234 10364563 11823426
SP1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160217 9339900 19753117
SP1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8940191 8184747 11026572 14593001 12217897 8910531 7896792
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10452548 21437359 2172788 18419748 9851700
SP1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12200149 11517158 15247904
SP1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14567977 22815527 21123453 14645238
SP1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11910354 12473536 9223667 15067326 21831840 17283128
IGF1 IGF1R â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11237532 12181198 17145802 19631971
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
IGF1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21798082 23331499 8452530 21071413 12067807 1852007 21645859 8408032 14604834 19258508 11287679 23675206 19029956 2877871
ESR1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19920132 17166846 22739988 10750020 11566442 20372799 8206951 9014838 24914937 11457856
IGFBP3 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10823924 11600567 22578544 1383255
NFKB1 BIRC3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21725609 23178297 23572150 9294162 9733516
NFKB1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15231833 15050749 19343319 17673602 17000776 11880364 10733571 9733516 18566231 12010810 15723831 10823821 11297551
NFKB1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513725 11313274 19164127 11027342 17031478 9733827
NFKB1 BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 15756023 9733516 12010810 18566231 16453001 20103608
CD40 BIRC2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
CD40 BIRC3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
RUNX1 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16007221 17589498 9209363 8577711 8585955
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9990015 19581927 10603305 15509789 16431920 19663997 15110775 7862113 10854425 17301242 24216764 20179325 15158467 17646392 18622014
CEBPA ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17360796 19620402 8756629 16247445 12949251
MET PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15611085 29435030 30134553 22188814 24043698 16782899 14572662 15247219 15561106 20802513 15598735
KMT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12453419 20210320 24680668 29897600 31485071 20541251 24235145 20452361
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 PBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19376833 18414489
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
HNRNPA1 GTF2F2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
GTF2A2 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2A1 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF13 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF11 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TBP GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7666533 8670811 11971135 8946917 9121468 9407004 7706261 16330756 7823952 7609077 8051080 8087622
TBP GTF2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 7969171 10675336 18206971 1644819 16412700 8051080 10581267 9566876 9003783 9603936 8751448 10617594 8552077 10078202 10523649 10985861 8626665 7823952 9343426
GTF2A2 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8626665 7724559 9603936 7958900 16713569
RARA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7556191 19538480 12935977
RXRG RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 25910212 25303530 23331499 20211142 15604093 21071413 10529278 21516116 25416956 31515488 16189514 32296183 16713569 18988627 29892012
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
POLR2A POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2E POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2F2 GTF2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7854423 11278533 31467278 11183778 8441635 16189514 8662660 7827505
SF1 EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9660765 16713569
REL BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12414938 23271966 11880364
PRMT1 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30354839 23152885 25192599 12183049 11850402 16169070 16713569 25810899
POLR2A POLR2C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105