AGTR1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
AP2S1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2M1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2B1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
ATF2
|
FGF21
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21317437
25055037
|
NFATC1
|
MYH7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15247427
17111365
|
GATA4
|
MYH7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10998641
10212267
|
NFATC2
|
NFATC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19564342
11786533
|
ATF1
|
ATP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9016641
7659506
|
ATF4
|
FGF21
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22233381
|
ATF4
|
PDGFRA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20617572
19648113
|
ADRA2A
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
1849000
|
DRD1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1832710
31160049
|
SSTR2
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
1374909
|
GNAI3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8327893
19703466
|
ADRA1A
|
CD81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
OXTR
|
CD81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
JUN
|
NPPB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16251994
11799083
|
CALM2
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
CALM2
|
PDE1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15082510
32196115
|
VEGFA
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11387210
11600407
|
CREB1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17464208
18471910
|
GATA4
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19501129
17975667
|
RET
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8628282
6730605
|
PLCG1
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9516477
6730883
|
PLCG1
|
RYR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PLCG1
|
INSR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
200301131
14568990
6804839
|
PLCG1
|
INSR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.8
|
0.8
|
mint
|
200301131
14568990
6804839
|
GRIN2A
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9231720
|
ERBB3
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16273093
|
FGFR3
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SCARB1
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
JUN
|
MAPK9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12832543
11192249
|
JUN
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
VEGFD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23157741
19136250
|
JUN
|
MUC5AC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
SLC26A3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1700011
22159277
|
MAPK9
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
JUN
|
MAPK10
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
AP2B1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
NFKB1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12456660
16135789
|
ATF1
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7499271
|
CREB1
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7499271
|
CAMK2A
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NFKB1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18031796
|
ERBB3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17308105
|
NFKB1
|
ADORA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9547356
|
NFKB1
|
AMH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15383177
|
FGFR3
|
MAPK11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPP3R1
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14697672
8195196
|
CREB1
|
ADRA1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10520459
|
CREB1
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10909971
22554507
|
CREB1
|
AGTR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11108142
24244341
|
CREB1
|
SOX9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17289023
|
CREB1
|
NPY
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12967770
|
CREB1
|
ADCYAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16006741
24018543
|
MAPK11
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11532940
11335727
|
PPP2R2A
|
PPP2CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1328247
19114990
|
PPP2R5A
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8287037
7592815
|
RYR1
|
PPP2CA
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8296396
18755143
|
PPP2CA
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7798931
9109540
|
CAMK2A
|
ATP1A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CAMK2A
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9768837
8798667
|
GNA11
|
PLCB2
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB2
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB2
|
PLCB3
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNA11
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12578375
27515033
|
GNA11
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNA11
|
PLCB3
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
ERBB3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
17496910
|
AGT
|
CPA3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
2443571
2708524
|
RYR2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20479242
1005843107
|
ADRB2
|
CCKBR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CAMK2D
|
ITPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23019322
|
GATA4
|
SLC8A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10212268
16966329
|
GATA4
|
AGTR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9207128
10579051
|
SRF
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11003651
11158291
|
SRF
|
SLC8A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10212268
16966329
|
PLCB3
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
ATF1
|
SST
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1655749
10766345
|
TRPV5
|
TRPV6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12574114
19295174
|
TRPV6
|
TRPV5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12574114
19295174
|
SCN5A
|
RGS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CALM2
|
ITPKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
ATF4
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
AGT
|
AGTR2
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.81
|
0.81
|
Signor
|
16597412
|
CD81
|
GNAI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32900848
30024968
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TRPV5
|
CREB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
PLCB2
|
RAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
CALM2
|
KCNN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
GNA11
|
EDNRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
10789830
|
TRPV5
|
ATF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AP2B1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
CALM2
|
RYR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CALM2
|
TRPV6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CALM2
|
RYR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
AGT
|
AGTR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
ATF2
|
MAPK11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ATF2
|
ATF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25609649
26344197
31964530
|
VEGFB
|
VEGFA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
25241761
8702615
33961781
26186194
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
INSR
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
ADRA1D
|
SNTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
CD81
|
GNA11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
32900848
30024968
|
CREB1
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
2138276
25609649
|
FSHR
|
FSHB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22802634
15662415
10395410
|
MAPK9
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9405416
|
AP2A1
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
33961781
26344197
|
RYR2
|
RYR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12213830
14722100
|
GNAI3
|
RGS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
AP2A2
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12086608
16189514
33961781
34079125
26344197
|
GATA4
|
SRF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11158291
11003651
|
CREBBP
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
AP2A1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
AP2M1
|
AP2S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24189400
33961781
26186194
19380743
26344197
|
AP2M1
|
AP2A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24189400
33961781
26186194
19380743
26344197
|
AP2M1
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24189400
33961781
26186194
19380743
26344197
|
AP2S1
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
12086608
16189514
33961781
34079125
26344197
|
CREB1
|
ATF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25609649
8384217
1655749
20102225
|
INS
|
INSR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
2550426
11278498
29512653
23302862
|
GTF2I
|
SRF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12082086
9584171
9334314
|
FLT1
|
VEGFB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
ATF2
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
NPPA
|
NPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
AP2B1
|
AP2M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
12086608
16189514
16713569
24189400
33961781
19380743
26186194
30021884
34079125
26344197
|
JUN
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8027667
20102225
28514442
16511568
23661758
15546613
26496610
2320002
20195357
10327051
1827203
9445037
20511396
10207054
25609649
33961781
|
NFKB1
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19752329
8016102
|
ATF4
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
1827203
20936779
23661758
|
CALM2
|
TRPV5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21576356
20686800
20926660
|
CALM2
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
CALM2
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
GIP
|
GIPR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15655707
17715056
12627975
8795084
7589426
|
GATA4
|
GIP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18343025
15486225
12686473
|
INSR
|
PLCG1
|
â—¼ COLOCALIZATION
|
|
|
3.0
|
0.9
|
intact
|
200301131
14568990
6804839
|
JUN
|
FSHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9794452
23178797
21659477
|
CREBBP
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12789342
16835236
|
NFKB1
|
KCNN4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
21725609
23178297
23572150
|
NFKB1
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10628750
8613256
|
PPP3R1
|
NFATC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11509611
10860980
16407284
|
CREB1
|
VIP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1847391
1347642
|
PPP2CA
|
VASP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7656973
8836115
|
CAMK2A
|
LIPE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9636039
|
EDNRA
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
7882989
10789830
|
PDGFRA
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
2466336
1374684
9739761
|
RET
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
MAPK9
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16648474
10978313
11274345
|
VIP
|
VIPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7811244
8390245
3899557
|
PPP2R2A
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
20711181
8288198
|
CALM2
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
SCN5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
DLG1
|
DLG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
12351654
26496610
|
NFATC1
|
PPP3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
JUN
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
GIP
|
GIPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
INSR
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
14568990
9593725
11796522
22974441
|
SNTA1
|
SCN5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
9412493
18591664
|
CACNA2D1
|
CACNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CACNA2D1
|
CACNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CALM2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
FSHB
|
FSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
PLCG1
|
RET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
32062451
8628282
25241761
16153436
|
AP2S1
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
31353312
16189514
7593184
33961781
26344197
|
JUN
|
MAPK10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
AP2A1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
AP2S1
|
AP2A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
33961781
26344197
|
CAMK2A
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
AP2A1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
INS
|
INSR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ATP1A1
|
ATP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
FLT1
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
AP2A2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
JUN
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ATF2
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
CREB1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
AP2B1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
AP2A2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
AP2B1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
AP2M1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
AP2A2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PPP2CA
|
PPP2R2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
ATF2
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10909971
17337306
21278380
|
ATF2
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10366004
10327051
8530413
12052888
15068801
12751796
9502786
9141200
9252389
11238729
12903123
19255142
11736649
16511568
9819389
|
MAPK10
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19436832
20506250
16393692
8654373
20028971
11274345
|
MAPK9
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17145710
17081983
18767875
20506250
25416956
19255142
19413330
20028971
8654373
12788955
11994493
11566021
10777545
7535770
8709204
17875713
20068231
16393692
15192015
7737130
18669648
10066798
602896
11896587
12110590
32296183
11971971
19651622
19436832
16533805
11865055
19822663
11823524
31515488
7737129
11274345
|
MAPK11
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
17145710
17081983
20506250
19690332
19413330
17079470
11566021
10085140
17254968
10777545
7535770
7839144
21614932
16393692
15304344
17380123
7737130
15192015
18669648
15187187
15140942
9235954
12110590
17258390
19436832
9155018
9430721
9029150
14734562
11274345
|
ATF2
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
25609649
20102225
15546613
2320002
10327051
1827203
9445037
26496610
20195357
16511568
20511396
10207054
8027667
23661758
31515488
18641343
1828107
|
ATF2
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18039929
20506250
12738796
11274345
8545107
17439715
|
CAMK2A
|
ATP2A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7929371
|
JUN
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8774698
24755082
8872603
20486760
20833713
18689604
|
CREB1
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17313370
19534727
14523007
|
AKT1
|
HMOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15581622
|
PPP3R1
|
NFATC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
PPP3R1
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10860980
16407284
16473827
11030334
|
NFATC1
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19915002
18078995
15657420
18299389
16455648
11402342
11030334
|
MAPK9
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
14517246
15184502
16648474
10978313
17570479
15958558
11274345
|
MAPK10
|
NFATC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16648474
10978313
17570479
11274345
|
ATF4
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18829529
20824063
14747470
15788408
20221394
24347168
23908598
18172307
18617696
23649506
22915762
18451308
|
ATF4
|
CREB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17669268
17434604
18441292
15240803
15888447
16121183
|
ATF4
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11564156
9295363
25241761
|
ADORA1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3805010
6305455
6162091
31160049
|
GNAI3
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
8327893
|
GNAI3
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
FGF16
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16597617
25772309
|
FGF16
|
FGFR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16597617
25772309
|
NPPB
|
NPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
2570358
|
INSR
|
CALM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
17389395
19901323
18578522
12153558
18707149
20068231
16497976
17287340
15592455
2843348
7925415
3415247
8639568
17016520
18669648
|
CALM2
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9952395
8625412
12379661
9728925
|
CALM2
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
CALM2
|
TRPV6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20926660
11248124
12765696
16959851
15123711
|
GIP
|
GIPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
12627975
26572091
17715056
8795084
15655707
7589426
15655705
|
GNA11
|
CYSLTR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10191087
3086311
16754659
1905813
8664309
|
FGF21
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22442730
16597617
|
FGF21
|
FGFR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16597617
25772309
|
VEGFA
|
FLT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16076871
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
VEGFB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
58.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19414323
19449109
19454690
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
VEGFB
|
â—¼ PROTEIN_INTERACTION
|
|
|
58.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19414323
19449109
19454690
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
FLT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16076871
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
NFKB1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18184402
17673602
16684540
15517885
12160329
15856023
18056465
20538607
17407600
20103608
|
JUN
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9256279
11204570
11353786
23274526
11678207
17341624
20015448
8910439
16328781
11731421
15039660
19553068
20432243
7887961
12163680
10885623
11281649
14602779
18294451
15277220
|
VEGFA
|
FLT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
15637071
9393862
8356051
10543948
21939755
8621427
16633338
21441409
35874709
8631822
14704231
17051153
20660291
26285753
22348123
|
VEGFB
|
FLT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16076871
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFB
|
FLT1
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16076871
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFB
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFB
|
FLT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
23331499
21071413
18988627
10409677
16633338
97517301
26285753
9751730
11181169
29397867
|
PLCG1
|
FGFR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
19147536
16091734
10652257
10918587
19749790
18337450
16844695
|
PLCG1
|
FGFR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
19147536
16091734
10652257
10918587
19749790
18337450
16844695
|
FLT1
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15501236
15520864
15573129
16002046
16076871
16572188
17086423
19414323
21372296
22064427
22461508
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
FLT1
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9299537
23331499
9398617
9600074
11312102
18988627
23397142
|
FGFR3
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17496910
12601080
17081983
16038803
1689310
1708307
7682059
15144186
8885868
16126727
15592455
8657103
16153436
|
FGFR4
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17496910
12601080
17081983
16038803
1689310
1708307
7682059
15144186
8885868
16126727
15592455
8657103
16153436
7518429
|
PDGFRA
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
23331499
12601080
17081983
16038803
25241761
1689310
1708307
7682059
15144186
8885868
16126727
15592455
7535778
8657103
16153436
|
CREB1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10471787
8647095
10403485
2140898
|
JUN
|
NPY
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8123590
17081520
12760745
8036020
|
JUN
|
OXTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10218980
15494465
16569740
|
JUN
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
1310538
9062890
9270011
7862133
20424231
22563476
14578290
8264634
|
MAPK9
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
17143273
17145710
17637567
12584171
20506250
11948398
15378002
16824735
9687508
8654373
20028971
12788955
9305638
15302935
26091349
33822843
18362184
17875713
16393692
9405416
17570479
1922387
18252863
25561726
7737130
10490605
17189706
11896587
34408980
11274345
20178741
8525045
16076903
7992057
19527717
7600582
17215518
8985011
11801649
19118012
11278395
8001819
8137421
19436832
16533805
8945519
12881422
9315636
10385525
12093796
14523011
19910486
15212693
8157646
12040039
11562357
|
CREBBP
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8028671
10327051
2138276
9659924
9786917
16713569
17296604
8545107
18443043
16055710
|
MAPK10
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17143273
20506250
16824735
8654373
20028971
16007099
21988832
12167088
16393692
1922387
16076903
22327296
19527717
21757544
19436832
17670986
14523011
11274345
20395206
11562357
|
JUN
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
2138276
1827203
18641343
8290251
|
CREB1
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
10866654
18599546
15585582
7870178
8028671
11313407
16007092
8413673
11564156
15691881
9829964
15073328
20403362
11259575
17476304
17707401
20541704
16799563
7870179
11123304
27789289
7913207
12933667
8663317
8004670
11483993
12198160
9413984
|
INS
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
29432553
23912456
11679435
23866690
17335965
24646332
23798298
|
RET
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12600984
15994200
|
PPP2CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
21159657
26256536
15743829
10026142
20452955
11438723
18559511
11839802
19996169
19216069
16406523
10995457
18042541
19556239
18588945
16680151
11087733
18160256
15367694
18039929
18077353
11812651
16044149
20360384
12637511
|
PPP2R2A
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
18039929
19216069
18077353
19556239
19996169
10026142
10995457
18042541
20452955
18559511
18588945
16680151
20360384
16406523
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
11175347
11756412
12356771
15733869
20452955
20398329
11160957
10217147
19216069
20214616
11463845
9829964
7958915
12235136
16680151
17646672
9687510
8887554
11698596
8688081
17680028
9528766
11018520
11969286
12519783
11909979
15725726
|
AKT1
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11809767
9032240
|
PPP3R1
|
NFATC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8576111
8631904
10860980
9727000
8799126
|
PPP3R1
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10860980
15364589
19285944
16407284
8631904
16473827
|
SRF
|
CREB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
15733869
28286024
15542842
9770464
1833716
18088355
7823924
7551568
15449318
2040600
|
CREB1
|
SST
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
1655749
8794339
1974651
7745688
1350057
8393039
1352885
7799950
1347642
|
CREB1
|
PPP2CA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17526027
19155497
19750005
|
CREB1
|
MUC5AC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17646388
22294049
24487386
18676374
|
CREB1
|
FSHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18550775
8592521
21986493
23393127
20008557
|
AKT2
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
20452955
9829964
20398329
17646672
10217147
|
AKT3
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
20452955
9829964
20398329
17646672
10217147
|
CAMK2D
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11175347
12356771
15733869
22554507
8887554
9528766
11018520
11698596
11160957
11969286
12235136
7958915
9829964
9687510
11909979
8688081
|
CAMK2A
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
11175347
12356771
15733869
1646483
11160957
9668047
7958915
9829964
12235136
11970864
9687510
8887554
11698596
8688081
9528766
11018520
11969286
11013247
11909979
|
CAMP
|
P2RX7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15067080
30847383
18765670
16493063
|
SOX9
|
AMH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9707325
24705165
21187121
12732652
9774680
14689607
11097782
11259267
|
ADCYAP1
|
VIPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
16930633
11978642
12488235
11931347
8146174
9928018
|
ADCYAP1
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
8703026
16930633
12488235
10583729
11931347
21350482
10100920
17470806
8253796
|
INS
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
8393875
21743783
21317886
24296476
26374090
29069585
26245346
16956584
19902173
20332342
23363978
23331499
18988627
23302862
22832498
2550426
15870194
11278498
19752148
29512653
23304064
24633815
17227660
22521887
23223021
30197476
|
INSR
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
28256297
8910597
8521811
17570479
8557631
|
INS
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20338882
25304263
30179516
23832510
23801578
22307032
20041157
24725432
|
PPP2CA
|
PPP2R5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
PPP2CA
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15367694
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
PPP2CA
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
15367694
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
CAMK2A
|
SRF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
11859076
12171911
10753652
12684542
8413226
10318869
|
CAMK2A
|
RYR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23059182
17643448
14715536
10830164
15790957
14532276
16709901
14514795
30571258
|
CAMK2A
|
DLG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15044483
12933808
|
CAMK2A
|
ITPKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11468283
9155020
9374536
|
SRF
|
NPPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16597624
11158291
9295358
17468179
|
GATA4
|
NPPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9584153
14573514
19546173
20384792
10075728
11994297
15542826
20874724
20931527
11382775
17584735
9312027
10330176
16603706
|
NPPA
|
VASP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
29391544
18079117
10922374
22216296
|
GNA11
|
PLCB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1333052
3017978
|
SRF
|
ACTC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15933209
11969255
8887666
17468179
9571041
|
PIK3R3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8596638
22402981
11733063
25814554
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
AGT
|
AGTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
2775266
21464395
8315512
21542804
17138938
8185599
15930094
9797979
8242249
7850406
|
MAPK10
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16648474
10978313
10652349
11274345
|
ERBB3
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16273093
17496910
24189400
|
CAMK2D
|
CACNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20194790
|
CAMK2D
|
SCN5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22514276
|
GRIN2A
|
DLG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12070168
9278515
11937501
|
FSHB
|
FSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15662415
17145710
2126341
10395410
|
EDN3
|
EDNRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
8460684
8086489
8904635
11982704
8001160
15629009
8440682
7524189
|
VIP
|
SCTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1646711
8390245
|
VIP
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
16930633
12488235
10583729
11931347
|
VIP
|
VIPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
68.0
|
1.0
|
Omnipath
|
9726637
16930633
9152366
9454823
11931347
12488235
12220741
8146174
9437714
9928018
10570056
10801840
|
FGF6
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
13851111385111
16597617
1385111
25772309
|
EDN3
|
EDNRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
PPP1R12A
|
ROCK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
ROCK2
|
PPP1R12A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
17127075
11062269
26664257
15281089
21242007
28971603
10579722
10047526
11331307
11739394
29955616
12220642
26701920
25168281
23825105
19997641
12600888
27251065
15003930
11931630
11719507
27725371
12563012
12919947
21273559
10601309
|
ADCY5
|
CAMP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
|
MAPK9
|
NFATC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
14517246
16648474
10978313
23047924
9374467
9630228
11274345
|
SST
|
SSTR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
67.0
|
1.0
|
Omnipath
|
7908405
9724791
15333679
9784130
9600011
9650799
8769372
11520208
9652348
7988476
10598788
|
SST
|
SSTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
9724791
15333679
9784130
8702767
9650799
1346068
8769372
11520208
9652348
7988476
10598788
|