Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CEBPG PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16227626 15778982
CEBPG PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9774647 8626491
CEBPG PTGER4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16061473 19347285
ERLIN2 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15050920 10579907
MYOD1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10805738 9988769
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
MAPK1 PPP2R5C â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16456541 5218298
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
SNTB1 MAPK12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 29681515 10212242
MAPK12 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9069290 9384584
MAPK3 PPP2R5C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16456541 17200115
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888388 16691505
MYOD1 MYL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1581290 8589760
PPP3R1 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10860980 16407284
PRKACA NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10611249 11749379
PPP2R5C PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
PPP2R5C CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8386317 8195196
ATF4 FGF21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22233381
LIN7A CASK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16688213 5218615
CALM2 PDE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082510 32196115
CALM2 PDE1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3021730 32196115
TBP GAL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17919657 11485989
MYOD1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18094043
MYOD1 ACTC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
VEGFA PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11387210 11600407
SP7 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22110141 22750006
CREB1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17464208 18471910
MYH9 CASQ2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLCG1 RYR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 FLNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RXFP3 GNAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ADORA2A GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8995267 6162091
GNAS ADCY4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
GNAS ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
MYB IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1349016 11486019
CREB1 IL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CREB1 CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11874984
MYLK2 MEF2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21556048 8189000
MEF2C MYLK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 21556048 8189000
MAPK11 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9069290 9858528
MYLK3 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21556048
PPP3R1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14697672 8195196
GNA13 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10821841
CREB1 ADRA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10520459
CREB1 NTS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7791794
CREB1 ADCYAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16006741 24018543
MAPK11 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11532940 11335727
KLF6 ADCYAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10646500 21329727
PPP2R1A PPFIA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CREM PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18721873 12533437
PRKACA ITPKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9374536
PRKACA GABBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11976702
PRKACA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8657310 9660757
GNA11 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA15 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
ADRA1B GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9481484 31160049
ADRA1A GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 1334487
S1PR3 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10488065 31160049
F2RL1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9349532 31160049
GNAQ PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GRIN2B CAMK2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8294337 19453375
CAMK2A GRIN2B â—¼   COLOCALIZATION 2.0 0.8 intact 8294337 19453375
CAMK2A ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9768837 8798667
ACTC1 PLCZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTC1 TPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GNA14 GNA11 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA11 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA11 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12578375 27515033
GNA11 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
DLG1 MAP2K2 â—¼   COLOCALIZATION 2.0 0.8 intact 21615688 8182979
S1PR3 GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10488065
PPP2R5D PPFIA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
THRA PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9259323 2903439
ADRB2 GNA14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7797501 31160049
SNTA1 DMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221731 9356463
DTNB DMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9395493 5221780
GABBR2 GABBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218685 16724110
GNA15 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNA14 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
MYB NMU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15187020
GNA14 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
PRSS1 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9349532 10978167
F2RL1 ADCY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ACKR3 CXCR4 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
VIP VIPR1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11027527 15247290 23597562 807467
TNNC1 TPM1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CEBPD ATF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29601799 20102225
FLNC PLCG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 19293945
TPM2 TPM3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33961781
PDE1C PDE1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ADORA1 GNB1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
GNAS SCTR â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CALCRL GNAS â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CXCR4 GNA13 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11994484 23773523
CALCRL GNG2 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
GNG2 SCTR â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
GRID2 GOPC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12372286
CALCRL GNB1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
GNA11 GNB1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
GNB1 SCTR â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
AMFR ERLIN2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
BRAF MAPK1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
GNAQ VIPR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11981043 11812005
CALM2 RYR1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CREM CREB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7809053 16189514 22531917 25609649
TBP CREM â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10409662 16713569
ADRA1D SNTA1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
PPFIA1 PPP2R5D â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CASQ2 TRDN â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ATF4 NFE2L2 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
TRDN CASQ2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11113462 9287354 11069905 7721813 10748065 14638677
CACNA1S CALM2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CTNNAL1 DMD â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
TPM1 TPM3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HOXA1 P2RY6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
TPM1 TPM2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ATF4 CEBPG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 16189514 25416956 23661758 1371974 20211142 20102225
ERLIN1 ERLIN2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CALCRL RAMP3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GNAS PTGIR â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PLCB1 GNAQ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16754659 12193606 11753430
TPM1 TPM3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 26186194 26344197
CASK DLG1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
BRAF MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK1 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MEF2C MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9069290 17210568 9988769
BRAF MAPK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 PPP2R5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16456541
ROCK2 MYL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25412762 22120626
RELA SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18477483 19538137 17665043
NFE2L2 ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21087962 23618921 20185790
CALM2 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2022671 7685187 8417150
CALM2 MYLK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 156362 28461506
GNAS ADORA2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 17371980 17909080 18758473
GNAS ADORA2A â—¼   SHARES_COMPLEX 3.0 0.9 ACSN 17371980 17909080 18758473
GNB1 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15782186 16189514 26186194
GNAS ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690
GNAS ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
ADORA2A IL2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 17371980 17909080 18758473
PPP3R1 NFATC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11509611 10860980 16407284
CREB1 VIP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1847391 1347642
CREB1 DBH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8753872 9763470 9341190
CEBPD PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12791769 1714459 11278589
GNA12 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12515866 11094164 12024019
PPP2R1A GNA12 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8238530 15525651 400508200
PTGIR GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10446129 31160049 11443126
AKT2 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10869359
PPP1CC CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8753794 9109540 12928489
CAMK2A GABBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20643921
TPM2 TPM1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 7568216 33961781 26186194 3857586 30021884 22939629
GLP2R GCG â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9990065 10322410 15471943
TRDN RYR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10531621 9287354 11069905 10212196 7721813 14638677 9890886
VIP VIPR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7811244 8390245 3899557
NR3C2 HTR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9191104 9284345 11278286
OPRL1 GNA14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9862775 16189514 31160049
CALM2 CAMK2A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CALM2 CAMK1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
DMD SNTA1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ACTA2 ACTC1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ADM CALCRL â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATF4 CEBPG â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
DLG1 LIN7A â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 14960569 24366813
NMUR2 NMU â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10899166 10894543 10887190
NMUR1 NMU â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10899166 10894543 10811630
CASK LIN7A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CACNA1S CACNB2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ADCY9 GNAL â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
DTNB SNTA1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 10545507 10747910 33961781
ADCYAP1 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ADCYAP1 GNG2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
DMD DTNB â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
GNAS GNG2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
SNTB2 DMD â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22937058 33961781 8576247
DTNB DMD â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 25416956 10545507 33961781 9395493 16448387
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SNTB1 DMD â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 7844150 8576247
DMD SNTA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 8612778 10747910 18468998 7890602 9412493 8576247 33961781 11571312
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GNAS GNB1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MAP2K2 MAPK1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
GABBR1 GABBR2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CAMK2A GRIN2B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPFIA1 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A PPP2R3B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
BRAF MAP2K1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPP2R1A PPP2R5C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MAPK1 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
NFE2L2 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19454702 23708697 17467702 21808062
MAP2K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 21675959 11704645 9694850 17081983 7565670 12750173 19690332 12932319 11823456 18799465 15592455 11337027 18083107 21365009 12788955 11134045 19219045 17389395 9447970 15342917 23331499 19534553 17569879 7559390 23047924 8226933 8223433 17272394 15851026 15811950 19494114 18988627 18669648 11549292 23519423 19541618 18691976 1381507 16293107 17906627 11986622 19933846 8376945 19053285 16094384 11971971 17192257 11136732 11948414 8388392 7898932 9731057 11730323 18039929 11118451 19369195 12920017 15951569 15466214 10746662
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11287604 11481231
MAPK1 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15657420
MAPK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 14654779 21478863 19541618 16508002 19710016 19933846 15664191 29335436 8621729
MAPK1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15073167 16888388 16691505
MAPK1 SPHK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16522638 14532121
MAPK1 PPP2R5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16456541
MAPK12 MEF2C â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10805738 9988769 9069290 9858528 10330143
MAPK12 SNTA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17081983 18669648 20068231 19413330 10212242
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAPK3 SPHK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16522638 21075214 15623571 14532121 16243846 19914200 18852266 19830907
MAPK3 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11287604 11481231
MAPK3 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15657420
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
MAPK3 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 8798443 8960373
ATF4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18829529 20824063 14747470 15788408 20221394 24347168 23908598 18172307 18617696 23649506 22915762 18451308
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
NPPB NPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2570358
NPPB NPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7901875 15709752 29934641 1309330 8700153
CALM2 TRPV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109716 19864432 12808128 14699077
CALM2 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3006921 17353931 20668654
GALR3 GAL â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9832121 9722565 1710578 1722333 7524088 9685625
GAL GALR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 9832121 9880084 9722565
MEF2C MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15743821 9418854
PRKACA CACNA1S â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20937870 2844809 1322891
VEGFA PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
RELA VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18184402 17673602 16684540 15517885 12160329 15856023 18056465 20538607 17407600 20103608
PPP1R12A MYH9 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PRKACA PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 1370476 2479646
GCG GNAS â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15569269 8405712 19859570 17306374 17900700
ADORA2B GNAS â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
ADORA2B GNAS â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
ADRB2 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12036966 15782186 23798571 6149763
GNAS ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9228084 9395396 1719547 9268375 21406690
GNAS ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9228084 6935665 210183 17652154 2022671 21406690 32196115
GNAS ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9228084 9748257 9268375 21406690
CREB1 RELA â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 RELA â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
PRKACA RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
RELA IL2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10679398 12133954 12759422 14668329 15079071 15536066 17145890 17404308 17550372 19171876 20138012 21224476 23430059 8383323 8580069 9743347
CREB1 RELA â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
RELA IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 7623820 8814256 22427656 9417120 9605137 15477007 9111330 21832163 9135552 8383323 8934574 11035116 7730629 16275766 9737979 19968887 28199730 1604322 15585831 8977179 12027419 18045535 18207244 17179947 23578476 15710339 9233628 11145913
RELA IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7957928 15331713 9446577 8035474
RELA CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20068066 12690099 16267013 20157762
PRKACA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11931769 15833743 9150141 17959673 9660950 16135789 12628924
NFATC3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7739550 9017603 21642596 17513763 7730629 8543769
CREB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11313407 12370343 17548609 12626549 15993752 12432566 8670878 8814256 11238674
CREM IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17056544 23124208 12370343 17237447 22942433 15841182 8622971 10586058 12626549 21976679 9545284 23019580 11238674 15322221
PRKCQ GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
PLG F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12604689 10978167 9020112
MEF2C MAPK11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10805738 9988769 9069290 9858528 10330143
MYLK2 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21556048
PPP3R1 NFATC3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8576111 8631904 10860980 9727000 8799126
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 CGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11518798 10341006 15637148 11014230 21986493
CREB1 GRIN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15774772 16313514 23012887 22364833
CREB1 MUC5AC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17646388 22294049 24487386 18676374
AKT2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
CAMK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8065343 15733869 7608156 1646483 9770464 9829964
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
CAMK2A CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11175347 12356771 15733869 1646483 11160957 9668047 7958915 9829964 12235136 11970864 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11013247 11909979
CREM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22531917 16189514 7809053 1847666
CAMP P2RX7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15067080 30847383 18765670 16493063
CALCB CALCRL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2177866 8626685 2985435 6609312 14722252
CALCRL ADM2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8387282 11693189 10217420 9620797 14615490
ADM2 CALCRL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21658025 14615490
ADM CALCRL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11693189 10347248 9620797
CALCB CALCRL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11693189 8626685 3001670 12196113 12234182 14668209 10347248 9620797
ADCYAP1 VIPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 8791009 16930633 11897681 12429744 12488235 11931347 9928018
ADCYAP1 ADCYAP1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 8703026 16930633 12488235 10583729 11931347 21350482 10100920 17470806 8253796
GNA13 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12515866 11094164 12024019
ADORA2B GNG2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
GNB1 GNG2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PDYN GNG2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
ADORA2B GNG2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
GNB1 GNG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
GNG2 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
PDYN GNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
ADORA2B GNB1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
ADORA2B GNB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
PRKACA CACNG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19968761 11805122
CAMP PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 15539636 7935349 16460834
PRKACA RYR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14532276 8380342
PRKACA HRH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15107581 15328002
PRKACA PPP2R5D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9688562 17110335 17301223 29294329
PRKACA PDE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2839485 16153182
PRKACA BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11510412 10931830
PRKACA GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12399457
PRKACA VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8182057 20058876 20166139 14679200 7925440 8836115 94237860 16197368 10851246 9685341 17287340 10922374 12576312
PRKACA ADRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9461522 24003153 10753752 11146000 2987243 27481942 27646272
PRKACA CACNB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10567342 10441130
PRKACA PDE3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 26031333 8163498 2839485 10454575 17255105 8626720
PDYN GNAQ â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
GNAQ PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11753430 1309799 12193606 16754659 8245028 8387502 1322796 1846707
BRAF MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 20212043 7706312 25437913 9560161 7936666 14970219 18567582 18332145 8413257 23331499 15342917 21071413 7731720 7873542 26496610 10976102 18988627 17667937 16255777 8131746 16888650 15485920 8394352 15175348 15466476 19541618 25600339 25155755 17563371 16810323 8157000 17979178 18039929 94178255 23934108 7835430 7624324 24746704 16135787 7935374 8039496 8621729
BRAF PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
MAPK11 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
CAMK2A SLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 32668157 19631655 27378083 23455424
CAMK2A GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12147342 11306676 19453375 21610080 16120608 8940188 11459059 22427672 16436603
CAMK2A HRH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15107581 10101032
CAMK2A DLG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15044483 12933808
PDYN GNA11 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
GCG GLP2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24990862 11738243 9990065
THRA CGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20352046 9709914
RAMP3 ADM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8387282 11693189 10217420 9620797 14615490
ADM RAMP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11693189 27391260 12565884 30139742 15692146 10347248 14712479
NMU NMUR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 15331768 15292653 10899166 10887190 10894543
NMU NMUR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15331768 15292653 10899166 10811630 10894543
VIP SCTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1646711 8390245
VIP ADCYAP1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 16930633 12488235 10583729 11931347
VIP VIPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 92.0 1.0 Omnipath 9437714 8791009 11027527 16930633 9152366 10655511 15247290 8390245 9928018 10570056 807467 9726637 9454823 10801840 10655512 11897681 12488235 11931347 8074647
AKT2 PDE3B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10454575 9421418 10779773 22001403
GNA14 PDYN â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
PDYN GNA15 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
PDYN OPRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 9686407 9262330 1967312 7624359 8170987 17503481 7869844
THRA TSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22570333 7999028 20838640 1335239
PPP1R12A ROCK2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
ROCK2 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17127075 11062269 26664257 15281089 21242007 28971603 10579722 10047526 11331307 11739394 29955616 12220642 26701920 25168281 23825105 19997641 12600888 27251065 15003930 11931630 11719507 27725371 12563012 12919947 21273559 10601309
RAMP3 ADM2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8387282 11693189 10217420 9620797 14615490
CALCB RAMP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11693189 26423127 15692146 10347248
ADM2 RAMP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27013657 21658025 20596793 30139742
NR3C2 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11216640 10329476 9694812
ADCY5 CAMP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23109003 15539636 7935349 16460834
GRP BRS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11112777