NEK7
|
TUBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NEK7
|
PPEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
H2AC14
|
CTPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
NEDD8
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
intact
|
0806155105
18723677
|
MYC
|
AIMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11085504
|
TRAF6
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0906941106
19955404
|
YWHAZ
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
COPS5
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18926707
|
YWHAZ
|
CTPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAZ
|
DDX3X
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
EEF2
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
MAP1LC3B
|
GRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
OTUB1
|
GRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TUBB
|
IKBKE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
LRRK2
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19302196
|
OTUB1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19996094
|
YWHAB
|
PPP5C
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16892053
21779496
|
PRKCA
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11950841
16713569
|
VCP
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TUBB
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TUBA1B
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAZ
|
TUBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
TUBB
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
TUBB1
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAB
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
CFTR
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
NEDD8
|
OTUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
24654937
18954305
33665565
|
OTUB1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
20622874
34591986
19996094
|
CFTR
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
812.0
|
0.81
|
STRING
|
36370105
|
CFTR
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
812.0
|
0.81
|
STRING
|
36370105
|
TRAF6
|
AIMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27197155
17353931
|
CUL3
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22709582
21145461
|
CUL4B
|
DDX3X
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34026424
21145461
|
TRAF6
|
DDX3X
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27507811
17353931
|
TUBB
|
TUBB1
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
EEF2
|
ETF1
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
LRRK2
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
CUL1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
TUBB1
|
TUBB2A
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
CAND1
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CUL1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.84
|
STRING
|
36370105
|
CUL3
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26344197
21145461
|
NEDD8
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24654937
10597293
18274552
21145461
16503656
23201271
31973889
16620772
|
TUBA1B
|
TUBB1
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
AIMP2
|
PARK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
TUBB
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
TRAF6
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
CFTR
|
GRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
26618866
29924966
17110338
31324722
|
YWHAG
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
TUBB
|
TUBB2A
|
â—¼ CORRELATES
|
|
+
|
0.88
|
0.88
|
CCLE
|
31978347
|
YWHAB
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
GART
|
PAICS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
SPRTN
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
CFTR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
COPS5
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
CAND1
|
CUL1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
12504025
12504026
15537541
|
MYC
|
CUL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10970882
12835716
|
MYC
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16376880
16915296
|
CUL3
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21145461
21249194
22013077
16449638
22405651
26286618
12609982
|
PRKCA
|
CTPS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17463002
|
NEDD8
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18805092
24654937
33961781
18274552
10597293
21119685
21145461
23201271
24076655
18247557
28522566
22405651
31253590
28514442
20847044
|
YWHAZ
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
VCP
|
SPRTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22902628
23042605
23042607
|
YWHAG
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17085597
15324660
|
YWHAB
|
YWHAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17085597
15324660
|
LRRK2
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
TUBB1
|
TUBB3
|
â—¼ CORRELATES
|
|
+
|
0.91
|
0.91
|
CCLE
|
31978347
|
TUBB
|
TUBB3
|
â—¼ CORRELATES
|
|
+
|
0.91
|
0.91
|
CCLE
|
31978347
|
TUBA1B
|
TUBB
|
â—¼ CORRELATES
|
|
+
|
0.91
|
0.91
|
CCLE
|
31978347
|
CAND1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
COPS5
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
TUBA1B
|
TUBB2A
|
â—¼ CORRELATES
|
|
+
|
0.92
|
0.92
|
CCLE
|
31978347
|
COPS5
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
TUBB2A
|
TUBB3
|
â—¼ CORRELATES
|
|
+
|
0.93
|
0.93
|
CCLE
|
31978347
|
CAND1
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
CUL3
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
TUBB
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
TUBA1B
|
TUBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
TUBA1B
|
TUBB3
|
â—¼ CORRELATES
|
|
+
|
0.94
|
0.94
|
CCLE
|
31978347
|
CUL1
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17290223
5219620
|
NEDD8
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
23401859
24654937
18274552
10597293
10318914
21145461
31444342
18826954
16503656
23201271
18247557
19617556
18173839
17132228
10585493
16620772
|
TUBA1B
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
CAND1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
COPS5
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
COPS5
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
NEDD8
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
21765416
16177058
18723677
18627766
17438373
32726803
24654937
11027288
18274552
10772955
16503656
24076655
18247557
22405651
17318178
10713156
19713960
10318914
21102408
23267066
23201271
22959436
17206147
16620772
18805092
10597293
21119685
21145461
18826954
19245792
19617556
12565873
18264111
24949976
22474075
|
CUL2
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
CUL5
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
TUBA1B
|
TUBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ETF1
|
GSPT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CAND1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CUL1
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
NEDD8
|
â—¼ SHARES_COMPLEX
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
NEDD8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
CAND1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
45.0
|
1.0
|
Omnipath
|
17145710
12684064
25435324
36076154
23019411
18826954
17290223
17438373
21169563
27542266
16036220
21145461
21778237
22474075
22767593
16861300
18173839
12504026
12504025
12706828
22405651
21249194
23453757
22013077
17439941
12609982
15537541
|
NEDD8
|
CUL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16620772
15688063
11696557
21145461
|
PRKCA
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
92316961
15212693
26888287
1377674
|
CUL4B
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
VCP
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
33444648
11733065
28115426
15652483
10811609
29153394
|
MYC
|
PAICS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12695333
|