Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYC LAMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11085504
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
CEBPB LNPEP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11798181 11517297
IKZF2 IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 9560339
AGT CPA3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2443571 2708524
AGT ANPEP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 15687497 17803194
AGT AGTR2 â—¼   UP_REGULATES ✅ + 0.81 0.81 Signor 16597412
LNPEP TNKS2 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
IKZF1 IKZF4 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
ACE AGT â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
IKZF5 IKZF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 16189514 33961781 10978333
ACE2 AGT â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
AGT AGTR2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
RAB5A AGTR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 11682489
IKZF3 IKZF4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
IKZF2 IKZF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9560339 16189514 33961781 28514442
IKZF1 IKZF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9155026 26823144 33961781 10204490
TFAP2A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9632747 8276360 7555706
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
MYC NRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ACE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
IKZF1 LNPEP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11798181 15894523 16364975
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
ESR1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
IKZF4 IKZF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10218586 10978333 33961781
IKZF1 IKZF5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10978333 30217970 33961781 27107012
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
IKZF5 IKZF3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 25416956 10978333 33961781
IKZF4 IKZF3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 10978333 26186194
REN AGT â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 22193701 12045255 12927775
AGT MME â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15283675 17704566 14747736
AGT CTSG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6807977 9570564 20889553
CTSG AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11747312 10899625
IKZF4 IKZF5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 10978333
AGT REN â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CANX RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
LNPEP RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TCF4 MYC â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10391247 11955436 11967263 12051714 15001769 15082531 15576399 16039586 17143292 17936032 19619488 20705860 22290435 22761862 23343194 24023259 25730849 7542250 8666229
TCF4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21533051 19778454 15928669 20133699 18852287 19561604 19662654
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
TCF4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
KRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
NRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11500490 18444174 16107878 10318842
AGT ACE â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 6269175 2846041 1848554 10536878 2558510 12540854 3017438 6270633 1668266 1851160
ACE AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11076943 10969042 23056909 15283675
REN ATP6AP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1204525512045250 12045255
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15283675 10969042 10924499 11815627
ACE2 AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969042 11815627
AGT CMA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11502696 10899625 6807977 2266130
REN AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16816138 12045255 20927107
AGT REN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32201502 12045255 20927107
AGT MAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1282979212829790 12829792
AGT AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12006574 21464395 10193788 10993080 16189514 15930094 9797979 16597412 17346243
AGT AGTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 2775266 21464395 8315512 21542804 17138938 8185599 15930094 9797979 8242249 7850406