Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LRRK2 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
BABAM1 BABAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SHMT2 KASH5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KASH5 SHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRB2 ATP5F1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
SHMT2 KIAA0895 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATF2 SIRT4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33861966
CMTM5 CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SHMT2 CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GRB2 DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DYNLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 SHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
RNF113A ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MYC SHMT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18628958
NDUFAF5 NDUFAF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24191001 20552642
RIPK4 CUL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 29435596
LRRK2 AIFM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
CFTR AIFM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
AIFM1 SFXN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 27218139
LRRK2 SFXN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
MYC U2AF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
CUL1 FBXO7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL3 ARMC5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 33130828 21145461
PDHA1 PDK1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
MYC NIT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
BRE BRCC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20656689 17353931 19615732 19261748 30755420 14636569 19261746 21282113 20032457 19261749
MYC PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
BABAM1 SHMT2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BRCC3 BRE â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRCC3 SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRE SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRE FAM175B â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
FAM175B SHMT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BABAM1 FAM175B â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
BABAM1 BRCC3 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
BRCC3 FAM175B â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BABAM1 BRE â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AIFM1 NDUFS3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFA4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFS3 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFA4 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFA4 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFS3 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
ATF2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
PRKCE ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24727247 22304920 24357804 25545367 26645581 25728676
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLD PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
PEBP1 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11585904 23331499 23180781
MAP3K7 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
MYC PDK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 11283613 11283614 11704864 16517405 16517406 17055429 17558397 17785433 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC NDRG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11936845 18455888 10381566 21976667
NDUFA4 NDUFS3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFS3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PDHA1 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 22195962 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
PDK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11222751 18691976 10075713 9768361 9748166
PRKCZ PEBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20166139 10891480 20068231 12551925 14654844
PRKCE PRKD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12058027