Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HECTD1 APC â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 22761442 23277359
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
SCAF8 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UTRN HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HIF1A SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23979441 23496980
UBA52 USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 UBA52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 26235645
VCP NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP UBE2D1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GMNN CDT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDT1 GMNN â—¼   PROXIMITY 2.0 0.8 intact 17318181 5219681
EXOC4 EXOC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 23037926
KPNA2 SUN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7993392 20551905
UBA52 NAP1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBA52 USP9X â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
SLC25A5 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFKBIA HIF1AN â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 17003112 0606877103
HSP90AB1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSP90AB1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HIF1AN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24421387 19726677
EIF4G1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10859165 5212678
SMC4 SMC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
HIF1A HSP90AB1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
RIOK2 RPS3 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EIF4G1 RPS9 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
YWHAB EPB41L3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
SFPQ FMR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 21653829
EIF4G1 GNB2L1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EIF2S1 EIF4G1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
NONO U2AF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21566083 26641092 26344197
SFPQ U2AF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21566083 22939629 26641092
CDC27 BUB3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27114510 22193957 33961781 32152539 32076268 21926987
TTLL1 CDC27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CUL7 OBSL1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AIFM1 SCO2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
EIF2S1 GNB2L1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
OBSL1 CUL7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21737058 31343991 25752541 21572988
PSMD2 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
AIFM1 PGAM5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 27218139 29568061
HSP90AB1 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
UBA52 ZNF622 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EXOC1 EXOC5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27173435
PGAM5 PHB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31536960 31177901 34079125
UBA52 USP7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EXOC1 EXOC4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GNB2L1 HIF1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PSMD3 UBA52 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HIF1A HSPA4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
UBA52 UBE2D1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PSMD12 UBA52 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
UBA52 UBE2D2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IGF2BP1 IGF2BP3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PSMD12 VCP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
NFKBIA VCP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PSMD2 PSMD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25036637 33961781 28292943 22939629 26344197
EXOC1 EXOC2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
DDX6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
NONO SFPQ â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
SFPQ NONO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17452459 18042045 11259580 21988832 25959826 30445466 12403470 31815296 30725116 34017080 33961781 24981860 17507659 30021884 22939629 26344197
SIRT6 UBE2D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2D3 UBA52 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EXOC1 EXOC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 33961781 27173435 19885391 26344197
EXOC4 EXOC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 90000000 19889837 33961781 27173435 19885391 31413325 17043677 26344197
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RIOK2 RPS9 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
EIF4A2 EIF4G1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
EIF2S1 RPS9 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
GNB2L1 RIOK2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
PSMD2 UBA52 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
HIF1AN HIF1A â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 6802010 19071119
EXOC4 EXOC5 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 27173435 26344197 23037926
EXOC2 EXOC5 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 27173435 26344197
EEF2 RPS3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RPS3 UBA52 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
EXOC4 EXOC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 21241894 27173435 26344197
GNB2L1 RPS3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
GMNN CDT1 â—¼   PROXIMITY ✅ 0.97 0.97 mint 17318181 5219681
RPS9 UBA52 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 UBA52 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 UBA52 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPS9 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 GNB2L1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RFC3 RFC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9488738 8692848 14681455 18245774 22939629 26344197
GNB2L1 RPS9 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
SMC2 SMC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 22939629 17268547 14532007 26166704 22863883 26344197 30021884 9789013 17113138
EXOC2 EXOC4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EXOC4 EXOC5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EXOC2 EXOC5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPS3 RPS9 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HIF1A HIF1AN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMD2 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD12 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDT1 GMNN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMC2 SMC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD12 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
APC USP15 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC USP15 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
SFPQ NONO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17452459 21988832 17145710 17507659 12403470 11259580 30021884 10858305 18042045 20421735 25959826
UBE2D3 HIF1A â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D3 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10329681
UBE2D1 HIF1A â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
GMNN CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 17145710 20980834 17318181 17261582 22581055 14993212 14578910 21543332 15232106 26496610 18617514 11125146 15257290 15855168 19906994 27107012 15138268 16482215 18162579 18184650
HSPB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12897149 9047237 16439988 19324872 18266962 14761954 9169414 10694513 19011223
UBE2D2 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10329681
EIF2S1 EIF4A2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
UBE2D2 HIF1A â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
HIF1AN HIF1A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11641274 12042299 12080085 12215170 22841746
HIF1A FECH â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15794924 14726529 20068160 18844219 18683594
HIF1A HIF1AN â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 6.0 1.0 Reactome 12615973 11823643 14701857 12042299 12080085 15239670
HIF1AN HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 12573436 11641274 14734545 12042299 12215170 12446723 17244529 19071119 17003112 12080085 19696166 16189514 19940151 24145445 26751287 12432100 26972000 17382325 19074848 26752685
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178