Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
TSC1 LZTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TSC1 GCC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FBF1 MAP3K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TSC1 NRBF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TSC1 GPATCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TSC1 FBF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SORBS1 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6804237 19116150
SNX9 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217519 15703209
RAB7A DNM2 â—¼   COLOCALIZATION 2.0 0.8 intact 20711168 8045116
DNM2 SNX9 â—¼   COLOCALIZATION 2.0 0.8 intact 5217519 15703209
NEDD1 HAUS6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0901587106 19369198
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
SNX9 DNM2 â—¼   COLOCALIZATION ✅ 0.81 0.81 mint 5217519 15703209
CUL4B RBM14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 28225217
RAC1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
LZTS2 FBF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 26638075
LZTS2 ADIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TXLNA IFT74 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAB2A RAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
HIF1N TXLNG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBF1 ADIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 26638075
MGST3 NMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CCP110 CEP290 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CTBP1 RBM14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 30217970
HIF1N TXLNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 29426014
PCM1 HAUS3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 24981860 26638075
PCM1 HAUS6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 24981860 26638075
PCM1 HAUS8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 24981860 26638075
PCM1 CEP97 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24421332 34079125 26638075
PCM1 PLK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 23345402 26638075
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HAUS8 HAUS6 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
OFD1 CSPP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 26638075
ADIP OFD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 26638075
DCUN1D1 LZTS2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CUL1 FBXL12 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CSPP1 PCM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 34079125 26186194 26638075
HAUS6 HAUS3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19369198 24981860 20360068
HIF1N FBF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16189514 33961781 26972000
OFD1 PCM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 24089205 26496610 26638075
IFT81 PCM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26638075 33961781 26186194 34079125
PCM1 NEDD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 26496610 26638075
CEP97 NEDD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 26638075
OFD1 C2CD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24997988 26496610
HAUS3 HAUS6 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TXLNA TXLNG â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TJP1 TJP2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PLK1 CEP97 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19596235 32707033 25659891
PLK1 OFD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26638075 21988832
TXLNA TXLNG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 27173435 22939629 21903422
ADIP PCM1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26638075 24397932
HAUS6 HAUS8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CCP110 CEP97 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
GCC1 FBF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 26638075
CEP290 CCP110 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 22441691 8392017
RAB7A RAB2A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 26344197 26496610
IFT81 IFT74 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 33961781 27173435 26186194
DNM2 SNX9 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CBL SORBS1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
PLK1 TP53BP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PLK1 CEP192 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26012549 25042804
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
FAS MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25241761 11495919
HAUS6 HAUS8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19369198 25173975 24981860 20360068
DNM2 GRB2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
GPATCH1 WDR83 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
HK1 RHOC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CEP97 CCP110 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 22441691 8392017
GRB2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5220480 7642581
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
IFT74 IFT81 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
STAM2 CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 31980649 8649804 8995445 25036637 23799367 11997436 8943292 9242692 10570290 8662998 11399323 10086340 7642581 9108392 20936779 11133830 8626404 17094785 8063801 9129019 8900205 15210722 8621483 25872741 25814554 9178909 16906159 8950973 17971399 10025673 9295052 19380743 9716598 16713569 11964172 9234717 8083187 7537740 8824292 9259313 9311917 7791764 17072306 14725908 33627783 9461587 9434624 9851874 8695851 12839496 17944804 11792427 10204582 8621719 11823423 9541596 33961781 169092 11263968 98621719 28514442 18273061 7592693 9174058 21706016 8995358 9872323 9233773 9367879 7544353 12941616 10829062 20124286 917890 15677445 9092538 10521482 8647120 19836242
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SORBS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15128873 9447983 17548467 12504111 12765336 11001060
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
DNM2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 CLTC â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
STAM2 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
TSC1 RAC1 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11955434 12829230 12906785 15611338 15851026 15967165 16636147 17680028 18974095 19022819 20146692
SNX9 DNM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 27107012 15703209 15299020 18388313
PRKACA LASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12571245 15465019 12432067 22665060 26061439 25225353