Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PRKAB2 TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
NPRL2 KICS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
NPRL3 KICS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
KICS2 SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25819761 26449471
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
PRDX1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17909037 19737972
SQSTM1 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
CUL3 SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25040165 23274085
DEPDC5 SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25819761 26449471
ITFG2 SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25819761 26449471
NPRL3 ITFG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
NPRL2 ITFG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
NPRL3 KPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
NPRL2 KPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
KPTN SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25819761 26449471
SQSTM1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NPRL2 SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25819761 26449471
NPRL3 SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25819761 26449471
PRKAB1 PRKAA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6767403 18480843
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAB1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAG1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
SQSTM1 PRKAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PRKAG2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAG3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
RBX1 SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
SZT2 SESN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25819761 26449471
SZT2 NPRL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28199306 28199315
WDR59 NPRL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25263562 28199306
PRKAA1 PRKAG1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
WDR59 SZT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28199306 28199315
NPRL3 WDR24 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
WDR24 NPRL2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23723238 28199315
NPRL2 SZT2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28199306 28199315
WDR24 WDR59 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KPTN SZT2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
DEPDC5 ITFG2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
ITFG2 SZT2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
KPTN ITFG2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28199306 17353931 26186194 28514442
DEPDC5 MIOS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
DEPDC5 SZT2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ITFG2 KPTN â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KEAP1 RBX1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PRKAA1 PRKAG3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
WDR24 SZT2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28199306 28199315
MIOS NPRL2 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NPRL2 WDR59 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
WDR24 NPRL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28199306 25263562 23723238 28199315
PRKAG1 PRKAB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 18480843 6767403
MIOS WDR59 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PRKAB2 SESN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24366874 22363791 18692468
AR SESN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16751804
KEAP1 CUL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15367669 28186440 15572695 20864537 25742418 33130828 20534351 20027226 30765703 32854194 23727018 25628777 26757824 17439941 16449638 16790436 21357422 19818716 32341456 20421418 22245129 26219975 22558124 32296183 24896564 15983046 30383469 18251510 24127568 22911784 33391509 15282312 20865015 24322982 21145461 20599909 17822677 22448038 18417180 30273379 15601839
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
PRKAA1 SESN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24366874 22363791 18692468
PRKAA2 SESN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24366874 22363791 18692468
PRKAB1 SESN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24366874 22363791 18692468
TP53 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17409411 18431400
PRKAG1 SESN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24366874 22363791 18692468
PRKAG2 SESN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24366874 22363791 18692468
PRKAG3 SESN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24366874 22363791 18692468
TP53 SESN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9926927 19226370 18431400
PRKAA2 PRKAB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRKAB2 PRKAG3 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
MIOS WDR24 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PRKAB1 PRKAG3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
PRKAA1 PRKAB1 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 17728241
MAP1LC3B SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
PRKAB2 PRKAG2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PRKAB1 PRKAG2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PRKAA1 PRKAG2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PRKAA2 PRKAG2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PRKAA1 PRKAB2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PRKAA1 PRKAG1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
KEAP1 SQSTM1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PRKAA1 PRKAB1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DEPDC5 NPRL3 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
NPRL2 NPRL3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PRKAB2 PRKAG1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PRKAA2 PRKAB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
DEPDC5 NPRL2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAA2 PRKAG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKAB1 PRKAG1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
CUL3 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
CUL3 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
SQSTM1 CUL3 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
KEAP1 CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20534351 30273379 15983046 24896564 15282312 17439941 32341456 26219975 32296183 26757824
RBX1 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
SQSTM1 KEAP1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15340068 16252010 20531300 21981924 23850759 25002027 26587781 26653790 26794443 27048822 28574505
KEAP1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20452972 20495340 22872865 15983046
RBX1 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
SQSTM1 KEAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 20378532 35044719 20495340 25416956 25939382 23117207 32075457 20452972 24322982 20562859 25910212 26043024 33397898 23795962 27631370 33603948 20421418 32296183 23242280 19615732 31169361 20173742 24011591 21482715
RBX1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 28380357 26117325 25040165 16286508 23274085
MAP1LC3B SESN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20452972 20495340 22872865 15983046
MAP1LC3B SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 18083104 23022382 35044719 26413874 25416956 22434781 31053714 24023838 19250911 17580304 23333919 20452972 24668264 28085563 21900206 20562859 20010802 25007327 32296183 33302793 24582747 33436498 16169070
PRKAA1 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 18480843 8626596 17728241 21232561 16306228 8663446 25852190 8621713 23455922
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
PRKAG1 PRKAA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20562859 10698692 26186194 9224708 17012231 16054041 25416956 31515488 32296183
SQSTM1 RBX1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
TP53 SESN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18692468 18431400 9926927
TP53 SESN1 â—¼   KO_DOWN_REGULATES ✅ - -2.21 2.2 PKG 28854368