Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBE2D2 CYLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25565632 31366726
TARDBP MATR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MATR3 RNF166 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBE2K MKRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP MKRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARP1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RNF166 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2K RNF41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIM9 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2E2 TRIM39 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
TRIM39 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM39 UBE2D3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM39 UBE2E2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MATR3 TARDBP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MAVS CYLD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30410068 18636086
CYLD TRAF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
XAF1 XIAP â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
UBE2D1 XIAP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
UBE2D2 XIAP â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
LTBR TRAF3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
TNFAIP3 TRAF6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
TNFAIP3 UBE2D1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
TRAF6 MAVS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31390091 21903422 32511263 20080758 30527812 26221961 31806368 23545497 22908223 29125880 26385923 16153868 27348524
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
SQSTM1 TRAF6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MAVS TRAF3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
TRAF3 MAVS â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 22792062 26221961 23545497 22908223 19893624 20080758 30527812 24622840 29125880 22022264 22079989 31390091 33411856 16858409 30267576 22901541 21200404 32324863 33608556 19419966 32511263 31806368 26519536 27980081 32366851 33582548 27348524
LIG3 XRCC1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
PARP1 LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
CYLD TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12917691 12917689 16230348 29933112 18382763
HERC2 XRCC5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
LIG3 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9705932 20227374 17353931 11163244 26496610 16713569 8264637 11352725 9136882
TRAF6 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18292600 9774977 10523862 10921914 17724081 15310755
MAVS TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22901541 19893624 17020950 18818105 21200404 16306936 18207245 19546225 22844514 22792062 19193783 34610835 16858409
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
TRAF6 SQSTM1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
TRAF6 SQSTM1 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
SQSTM1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15870274 27458013 10747026 27681126 16079148 16189514 18382763 16874300 11244088 17389358
TNFAIP3 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 17703191 18164316 20622874 15334086 23018911 9928991 23737552 23105109 31625129 11463333 21220427 18239685
XAF1 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 23323858 11175744 22811387 17613533 12766484
XIAP XAF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11175744 17435549 22733138 23070005 26587781
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368