Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RGS6 H2BC12L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L MTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAC1 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11950936
GRPR GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 17251915
ARFIP2 RAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CDC42 RPS6KB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CDC42 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438723
HSPD1 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8676499 16713569
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PAK1 RAF1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17097642 5219317
MRPL15 MRPL37 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MRPL15 MRPL27 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MRPL13 MRPL15 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
WASF1 RAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 31871319 9843499 19363480
MRPL24 MRPL37 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MRPL37 MRPL4 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MRPL19 MRPL37 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
MRPL13 MRPL19 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SSA27 MTG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
YBEY CH60 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PCH2 MTG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RM12 MASU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RM12 MTG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KCC2D MTG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MTG1 MASU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
YBEY MTG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MRPL19 MRPL37 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MRPL19 MRPL4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MRPL19 MRPL27 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MRPL19 MRPL44 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MRPL13 MRPL27 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RHOJ CDC42 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10967094 31871319
ISLR MTG1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RHOC RHOA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319 31980649
MRPL24 MRPL44 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RAD18 PAK1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
MRPL11 MRPL13 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CH60 MTG1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32877691
MRPL37 MRPL44 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
MRPL12 MRPL24 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MRPL12 MRPL44 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MRPL37 MRPL4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PLD1 CDC42 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 10747870
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
MRPL15 MRPL37 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MRPL12 MRPL4 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
PAK1 RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11733498 12551923 17097642 9823899 9234708 10205168
RAF1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15520807 17462920 20363321
MRPL12 MRPL37 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ARFIP2 RAC1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
MRPL11 MRPL12 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MRPL12 MRPL13 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
MRPL37 MRPL44 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
MRPL24 MRPL44 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
MRPL27 MRPL37 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
RHOA ROCK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MRPL12 MRPL19 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MRPL12 MRPL27 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MRPL12 MRPL15 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RHOJ PAK1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 31871319 32814053 10967094 28514442 14521508
MRPL24 MRPL27 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MRPL11 MRPL24 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
MRPL11 MRPL44 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
RAF1 MAP2K1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7014125 19197339
MRPL19 MRPL24 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7744004 12879077 23455922 15548653 10802735 24276241 31871319 10684602 21167153 19596003 12606577 10360579 18057010 20936779 11157984 25150978 18426980 21029865 12650940 9705280 8107774 23175184 21048135 31478661 9535855 16678097
MRPL27 MRPL44 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ROCK1 RHOA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31871319 14660612 31431478 8816443 21281639 8798490 12773565
MAP2K1 RAF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MRPL11 MRPL37 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MRPL24 MRPL37 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPL13 MRPL37 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MRPL13 MRPL24 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
MRPL13 MRPL4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MRPL4 MRPL44 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MRPL11 MRPL27 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MRPL13 MRPL27 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPL15 MRPL44 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPL11 MRPL4 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL15 MRPL27 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL15 MRPL24 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL19 MRPL27 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL11 MRPL19 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
MRPL13 MRPL44 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
MRPL13 MRPL15 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPL13 MRPL19 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPL15 MRPL19 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPL19 MRPL44 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPL24 MRPL4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPL27 MRPL4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MRPL11 MRPL15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MRPL11 MRPL13 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MRPL15 MRPL4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MRPL19 MRPL4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RHOA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11102529 12593858 9565577 11311142
RAC1 ARFIP2 â—¼   UP_REGULATES ✅ + 9.0 1.0 ACSN 11274345 11544274 11756498 18000759 19151919 24459205 27331412 9312003 9655398
RAC1 ARFIP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 29997244 16212495 8670882 31467278 12480336 11152757 16189514 11346801 9312003 11478794
CDC42 WASF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10360578 8643625 12181570 11052943 15834156
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
CDC42 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7600581 17161586 23109003 9487126 7601337 9305638
PAK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 18593598 27542844 21371233 22105362 22981863 18668521 27169363 12876277 31416844 23331499 33789117 7873542 29551131 28225038 19595712 11435472 9351825 25794709 9416003 21248166 14993270 23701950 18940914 16129686 11948406 23162738
RAF1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 143.0 1.0 Omnipath 10757792 18337766 18799465 15342917 23728975 26496610 15866172 17053865 11242034 9351825 9677429 8157000 7992057 11948414 11604401 16129686 10677502 12695496 19197339 7565670 12750173 7936666 1326789 19219045 23331499 18556463 10976102 18988627 15485920 15175348 18691976 16407412 10409742 9311917 17192257 7898932 8621729 23934108 11684694 21336309 7624324 12920017 11948406 15466214 11042690 12907640 9032297 27169363 12876277 8933152 8223433 8248196 8131746 12594221 10969079 10567369 17979178 17724343 24746704 19058874 10958680 8090753 21071413 7731720 7873542 1330321 8503013 16093354 19541618 8394352 15466476 25155755 11136732 9069260 94178255 8607979 10327068 10359597 8039496 20212043
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
MAP3K1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8385802 12048245 8131746 17110930 8034665 8019005 10969079 12456688
PAK1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24699410 12228228
RAC1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7600581 9487126 7992057 7600582 9733714 9305638
SOS1 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
PAK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 28007610 19421139 26333361 22096607 15849194 12952546 30197477 12551923 23162742 25733387 17097642 22105362 18465753 23331499 24924700 10801448 26257058 21917714 12719581 11376654 25843685 15664191 19165420 23576562 23506953 10205168 24505617 28415790 18775988 22983922 9234708 12952943 16129686 25472536 11733498 11948406 9823899 11897507
RHOA ROCK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11698448 11729192 11739775 11992112 12194823 12361600 12740575 14657501 14744429 15761148 17517963 18037882 18423981 20535745 21178402 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
RHOA ROCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 12361600 25010901 23151663 7479854 27048821 22949611 21281639 26885855 8798490 12727213 17673200 11729192 8816443 10592173 11698448 27066895 11739775 11992112 20535745 18423981 24857661 21178402 23109003 9660866 9822605 17517963 14660612 15774750 12740575 14744429 9535835 12773565 15761148 24919149 26192618 9362522 18037882 14657501 12194823
WRN MTG1 â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
RAD18 MTG1 â—¼   KO_DOWN_REGULATES ✅ - -1.17 1.16 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368