ADRB2
|
SNCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ADRB2
|
LAMP2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7291579
19424180
|
APLNR
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ORC5
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
EP300
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
HIF1A
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17382325
5219810
|
ESR1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
ESR1
|
HBB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14695898
18252963
|
ESR1
|
HSPA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11085516
|
HSP90AA1
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9038169
9151685
|
HSP90AB1
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9038169
9151685
|
VIM
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
HSPA8
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9038169
9151685
|
LAMP2
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9038169
9151685
|
HSP90AA1
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18538669
6550889
|
HSP90AB1
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18538669
6550889
|
USP19
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22128162
21849505
|
HIF1A
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12606552
15385570
|
HIF1A
|
HSP90AA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14726529
20068160
|
WDR31
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SOD1
|
LAMP2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8141566
21252941
|
SNCA
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SQSTM1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SNCA
|
PARK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0020362
15502874
|
PIAS4
|
VIM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
SQSTM1
|
SNCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SNCA
|
VIM
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16678164
5218597
|
SQSTM1
|
SOD1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8141566
21252941
|
HIF1A
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
HSP90AB1
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
UCHL1
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
32814053
18635949
18550537
|
CDYL1
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
BAP31
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31588230
|
LAMP2
|
RU2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22939629
34266953
|
DD19B
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
DC2L1
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
F105B
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CD029
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
COT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
PTPM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
CP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
F118B
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
GTPB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
GTPB8
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
HS12A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
MMSA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
BDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
FOLC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
PLCE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
BRF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CFTR
|
SFXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26618866
17110338
|
LAMP2
|
CHD1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LRRK2
|
CHD1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
26496610
|
HDAC6
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15102857
19344692
12718889
22778253
23133622
|
LAMP2
|
GNL3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
GPD1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
GUF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
TAZ
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LYN
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23503679
34079125
|
NPC1
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33144569
34079125
|
SFXN3
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RHEB
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32814053
28514442
|
TRUB2
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
SFXN5
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
XRCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
SRPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
34079125
|
LAMP2
|
ORC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
PPTC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
STK39
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
NEK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
MSTO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
LAMP2
|
RAB18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RNF13
|
COT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
TM192
|
LAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33545068
31995728
34079125
|
HDAC6
|
CFTR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31501480
14675537
22069321
|
RNF13
|
CLCN7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
LAMP2
|
HELLS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32814053
28514442
33961781
|
WDR59
|
SZT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28199306
28199315
|
HSP90AB1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
RHEB
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18550814
16098514
25351248
15854902
15878852
16915281
33157014
15772076
|
CREBBP
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
LAMP2
|
PDXD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
34079125
|
IFT88
|
IFT27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
27173435
|
CFTR
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
EP300
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HDAC6
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CREBBP
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
HDAC6
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
HSPA8
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
RPTOR
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
MDM2
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12897156
17545634
10766163
11178989
16713569
31012223
|
MAP1LC3B
|
NEDD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
CFTR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
HSPA8
|
ARL13B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
HSPA8
|
CETN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
HSPA8
|
CFTR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
MDM2
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9809062
11070080
16713569
|
EP300
|
HDAC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15102857
19344692
|
ESR1
|
LGALS8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ESR1
|
NEK6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
HSPA8
|
HDAC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
PCNT
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
PLIN3
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
RNASE1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
VIM
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
HSPA8
|
PARK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
HSPA8
|
IFT88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
HSPA8
|
PLIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25961502
2799391
2204156
|
TSG101
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11172000
17060450
|
HIF1A
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
HSP90AA1
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
MAP1LC3B
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
HSP90AA1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
RHEB
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
HIF1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
18268343
15154850
12914934
19074848
25192544
22789427
20829524
21148070
17502379
26826385
22075993
16543236
19680224
20603618
19589782
11063749
23618863
26135796
27808477
22219185
15155277
11823643
17906695
19666581
21187066
16189267
8917528
23746844
19940151
19071119
26944191
15261140
24421387
20000859
12778114
14691445
12042299
22684029
12588875
17382325
23966271
15342390
22735262
27320910
26751287
24821806
23448368
11959990
15280364
11940656
19696166
20620956
16081065
22908229
18047470
16847340
22807441
23880760
|
CDC6
|
ORC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
RPTOR
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
24036451
|
MTOR
|
RPTOR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.98
|
0.98
|
mint
|
21045808
8088164
|
MTOR
|
RPTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.98
|
0.98
|
Signor
|
19346248
|
CREBBP
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
MTOR
|
RHEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
EP300
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
HSPA8
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21148293
10666020
19878303
21697503
|
HIF1A
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12542982
20547241
17452336
15907483
19489936
15342390
15184875
|
CREBBP
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9192902
18765668
16417649
11113179
8616895
11782371
14766010
17400812
|
EP300
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
24821806
12573436
17145710
16847340
12588875
19589782
11940656
25192544
11959990
18519678
23448368
22219185
11823643
12042299
15342390
23746844
19071119
19680224
27808477
15154850
19696166
8917528
17906695
18268343
22735262
21148070
15261140
19940151
23880760
22807441
35430356
14691445
12914934
20000859
12778114
26751287
16081065
22789427
16543236
24421387
17382325
17502379
22684029
21187066
19074848
23618863
23966271
20603618
|
ESR1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23733894
15334655
16483936
12237295
20664923
|
ESR1
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12897156
17166846
12750288
8324731
22787161
21169420
19578757
|
HDAC6
|
HSP90AA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19158084
18591380
18266962
|
RPTOR
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
12150925
12777372
15755954
15854902
16469695
16915281
17991864
19299511
19864431
19942859
20484410
22025673
22841746
23087689
26159692
|
HIF1A
|
TNF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
28.0
|
1.0
|
ACSN
|
10754326
10804084
10952726
11875494
12907458
14660645
15465827
15644117
16110315
16127144
16878026
17404308
17485448
17533374
20427344
20535745
20855962
21051947
21765015
22006996
22850421
22988108
23390297
24006507
25043024
25103413
25732824
7594497
|
HIF1A
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
21386799
17451682
15604270
17548584
17884817
15925386
22320863
23359428
23085511
19766100
16007254
12479793
|
MDM2
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15880652
25535359
12606552
25447306
17234751
19696166
10640274
|
LYN
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
JAK1
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
LRRK2
|
SNCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20127702
22924508
22658533
24907399
19576176
|
LYN
|
SNCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
11162638
11078745
11744621
12096713
|
MAP1LC3B
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18083104
23022382
35044719
26413874
25416956
22434781
31053714
24023838
19250911
17580304
23333919
20452972
24668264
28085563
21900206
20562859
20010802
25007327
32296183
33302793
24582747
33436498
16169070
|
MTOR
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
SQSTM1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
25002027
26587781
28574505
|
MTOR
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RHEB
|
MTOR
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RHEB
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
18670866
18075516
18550814
16631613
18466115
16915281
23331499
15772076
16098514
20006481
15878852
21071413
23272152
19299511
15854902
19487463
20226003
19143635
17604271
16636147
17470430
12906785
|
RPTOR
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
139.0
|
1.0
|
Omnipath
|
15268862
24403073
20427287
22258093
21321085
19446321
15467718
19875983
17461779
12665511
12719976
16631613
21045808
21177249
23911927
24337580
25446900
24516643
18614546
12718876
12747827
16603397
17043309
18519641
22544753
25007995
27043084
19145465
23953116
19619545
16919458
24375676
15459249
16837165
16847060
25332233
12150926
22424946
26348909
12150925
18955708
20381137
22356909
17386266
17565979
18030348
16354680
20169205
19114562
21071439
27329724
35561222
16798736
15809305
22493283
17277771
15661536
16962653
1683716516603397
17604271
18676370
16183647
18505677
23297343
23872070
24036451
15066126
18570873
21614075
18722121
12408816
17599906
|
RHEB
|
RPTOR
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RHEB
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17604271
15854902
19299511
16636147
24337580
15878852
17470430
19143635
16631613
12906785
18466115
25446900
|
RPTOR
|
SQSTM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12150925
12777372
15340068
15755954
15854902
16252010
16469695
17991864
19299511
19864431
19942859
20484410
20531300
21981924
22025673
23087689
25002027
26159692
26587781
28574505
|