FOXO1
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20082134
18444242
|
FOXO1
|
LPL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12586369
16492665
|
FOXO1
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18444242
|
GPR35
|
MCOLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
AP1B1
|
CLTA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8909539
11050117
|
IGF2R
|
RAB9A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19490898
21421921
|
IGF2R
|
GGA3
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16977309
5219086
|
NGFR
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9195882
12692556
|
CAV1
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16890161
|
M6PR
|
RAB9A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19490898
21421921
|
M6PR
|
GGA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11387475
5214102
|
M6PR
|
LRP2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21971085
8306957
|
PPARA
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20146263
15314095
|
CTSD
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APOE
|
ATP6V0A4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BUD31
|
NPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
PPARA
|
LDLR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22593575
18852694
|
GPR35
|
NPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
MC4R
|
NPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
SREBF1
|
NPC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18272928
|
PPARA
|
ANGPTL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15190076
12099716
|
PPARA
|
PCSK9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16794006
18245819
|
ABCG8
|
ABCG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16870176
5218866
|
VDAC2
|
LRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VDAC3
|
VDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VDAC3
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GPR35
|
SCARB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
SREBF1
|
LIPC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22253973
15721010
|
SREBF1
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15123650
16885156
|
APOC2
|
LPL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10727238
11579204
|
CAV1
|
RHOA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
31871319
20460433
9647788
|
IDS
|
AP3M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
AP3M1
|
AP3B2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AP3M1
|
AP3M2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB7A
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
31871319
|
CDC42
|
VAPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
26344197
|
CAV1
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
19595769
|
AP3M2
|
AP3B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AP3M2
|
AP3D1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NPC1
|
RAB9A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
33144569
|
AP4S1
|
AP4B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26496610
|
AP1G2
|
AP1S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16713569
9733768
|
VDAC3
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NPC1
|
LAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
33144569
|
NPC1
|
TMOD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33144569
22939629
|
NPC1
|
T106B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33144569
33545068
|
NPC1
|
LTOR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
33144569
|
LITAF
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AP3S1
|
AP3M2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AP3M2
|
AP3S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ARSG
|
SUMF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GNS
|
SUMF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ATP6V0B
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
PTPRK
|
HYAL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IGF2R
|
GGA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
5214130
11390366
|
VDAC1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PTPRK
|
ARSA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ARSA
|
SUMF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ARSA
|
GALNS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PTPRK
|
NPC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
VDAC1
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31536960
22939629
29128334
|
PTPRK
|
ARSG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PTPRK
|
ARSB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PTPRK
|
GALNS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PTPRK
|
MANBA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IDS
|
PPT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IDS
|
SUMF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
15962010
33961781
26186194
|
IDS
|
GALNS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AP1B1
|
AP1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
AP1G1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
CDC42
|
TMOD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31478661
31980649
|
GGA2
|
GGA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
14638859
31076515
|
AP3B2
|
AP3D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
AP3B2
|
AP3S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
9118953
33961781
|
APOA1
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28183703
7592581
19164805
|
LAMP1
|
T106B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
29568061
33545068
|
ARSA
|
GALNS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
AP1M2
|
AP1S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
ATP6V0D1
|
TCIRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
APOA1
|
APOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10722751
24981860
3104518
|
AP1M2
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
GGA1
|
GGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
LDLR
|
MYLIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
ATP6V0D2
|
TCIRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
APOA1
|
APOC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15174051
11991719
|
RAB7A
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
26496610
|
AP4M1
|
AP4B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10436028
33961781
|
LRP2
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11421580
7768901
16713569
|
RAB7A
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31536960
26496610
|
VAPA
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26344197
26496610
|
LRP2
|
APOH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9727058
16713569
|
AP3S1
|
AP3M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
22863883
33961781
|
AP3B1
|
AP3M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
22863883
33961781
26344197
|
AP3S2
|
AP3M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
9182526
|
AP3M1
|
AP3D1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
23144738
22863883
33961781
26344197
|
AP3B1
|
AP3S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16189514
9182526
|
AP3D1
|
AP3S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15469849
9182526
|
AP4E1
|
AP4S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
AP4M1
|
AP4E1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10436028
33961781
26496610
|
AP4E1
|
AP4S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10436028
33961781
26496610
|
RAB7A
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
29360040
26496610
|
VAPA
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22939629
26344197
26496610
|
NPC1
|
NPC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20674861
27238017
|
VDAC2
|
VDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
22939629
30021884
|
ATP6V0A2
|
ATP6V0D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
LRPAP1
|
SORT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
VAPA
|
VAPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
APOA1
|
LCAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
AP1G2
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CLTB
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
AP3B2
|
AP3M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
AP3B1
|
AP3M2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
AP4B1
|
AP4E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CLTB
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
AP1B1
|
AP1G2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32296183
33961781
|
PLTP
|
APOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
9469594
|
LDLR
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24447298
12031600
|
APOA1
|
PLTP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11854286
9469594
|
AP1B1
|
LDLRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
ATP6V0C
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
AP3D1
|
AP3S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
AP3B2
|
AP3S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
LRP1
|
LRPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CAV1
|
LRP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
28966723
16890161
|
GGA1
|
GGA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14638859
33961781
28514442
|
AP4B1
|
AP4E1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10436028
26496610
11409905
32073997
33961781
|
AP1M2
|
AP1G2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
|
AP1M2
|
AP1S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
|
AP1M2
|
AP1S3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
|
LDLR
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24447298
12036962
20030366
|
HEXA
|
HEXB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16698036
33961781
|
APOA1
|
ABCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12084722
30458687
27017521
|
VDAC1
|
VDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31536960
22939629
29128334
30021884
|
CLTC
|
GGA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
LRP1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
2779654
11421580
20030366
15182176
|
SREBF1
|
LRP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20980003
|
CTCF
|
CIDEB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
PPARA
|
APOA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12118000
10774955
7635967
|
PPARA
|
APOA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19433068
|
VAPA
|
VAPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
19515777
16227268
9920726
26496610
33961781
26186194
34079125
|
PCSK9
|
LDLR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18250299
22081141
25613181
18753623
17435765
23085658
|
MYLIP
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
30896554
26666640
23382078
|
PPARA
|
SREBF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12730331
1273033
21540177
|
PPARA
|
APOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11925428
16542871
|
PPARA
|
CYP27A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11701475
15340076
17156732
|
ABCG8
|
ABCG5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12208867
16870176
27144356
|
LCAT
|
APOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
4335615
15654758
16189514
1644835
10026251
10222237
1587806
17676061
3104518
|
CTCF
|
ABCA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
SREBF1
|
SCARB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12470667
15486308
10579331
|
SREBF1
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11145563
11250933
11861536
|
SREBF1
|
LPL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9788252
18974273
11090277
|
AP1B1
|
AP1M2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
CLTA
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
AP1M2
|
AP1S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
28514442
10535737
16189514
33961781
26186194
|
AP3D1
|
AP3M2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
AP3B1
|
AP3D1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
22863883
15469849
22939629
26344197
|
ATP6AP1
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V0D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
AP1B1
|
AP1S3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
23415225
33961781
|
GGA3
|
M6PR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
NPC1
|
NPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
AP1B1
|
AP1S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
26496610
33961781
22939629
26344197
|
LDLRAP1
|
LRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
AP3B1
|
AP3S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
22863883
33961781
22939629
26344197
|
AP1M1
|
AP1S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
26496610
33961781
22939629
26344197
|
HEXA
|
HEXB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
AP1G1
|
IGF2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
AP1M1
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
AP1M1
|
AP1S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
AP1B1
|
AP1M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
GGA1
|
SORT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
AP1B1
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
AP1B1
|
AP1S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
AP3B1
|
AP3S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
AP1G1
|
AP1B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10535737
10747088
9733768
7593184
23415225
11409905
33961781
22939629
26344197
|
AP1B1
|
AP1M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
7593184
22939629
33961781
26344197
|
AP1B1
|
AP1S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
22939629
33961781
24843023
26344197
|
AP3S1
|
AP3D1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
15469849
23144738
22863883
33961781
26344197
|
AP1M2
|
AP1G1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
10535737
16189514
33961781
26186194
26344197
|
AP1G1
|
AP1M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10535737
10747088
7593184
22939629
26344197
|
AP1G2
|
AP1S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
16713569
9733768
26496610
33961781
|
AP3B1
|
AP3M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
ABCG5
|
ABCG8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
AP1B1
|
AP1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
AP1M2
|
AP1B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
10535737
33961781
26186194
26344197
|
AP1G1
|
AP1M2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
AP3D1
|
AP3M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
AP3D1
|
AP3S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
AP3B1
|
AP3D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
LDLR
|
PCSK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
AP1G1
|
AP1S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
AP1G1
|
AP1M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
AP1G1
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
AP1G1
|
AP1S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
10535737
16189514
10747088
9733768
7593184
15758025
22939629
26344197
|
CLTA
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
AP1G1
|
AP1S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
29892012
16189514
25416956
9733768
26496610
33961781
22939629
26344197
|
GGA2
|
IGF2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
GGA3
|
IGF2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GGA1
|
IGF2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
AP1S1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
AP1S2
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTC
|
AP1M2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTC
|
AP1M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTC
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTC
|
AP1S3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
FOXO1
|
SREBF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24478438
16492665
18202130
20868688
22511764
|
FOXO1
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21817852
19463968
16885156
19237543
|
PPARA
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16985262
18391971
|
PSAP
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9707421
|
LRPAP1
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
10747918
1718973
1374383
14596620
20030366
|
CLTA
|
AP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
LRP2
|
LDLRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
14528014
23836931
7768901
8710919
8706697
|
PPARA
|
CD36
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12118000
12419306
9642225
16713233
11867619
20110263
16556603
16890192
|
CDC42
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16714282
7512369
9113980
23434736
11306516
|
AP1G1
|
CLTA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
AP1M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
AP1M2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
AP1S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
AP1S3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
APOE
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
12036960
24447298
31677479
20030366
12036962
15840700
11327878
|
SREBF1
|
LDLR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12180145
8402897
9651391
22153697
7597088
14998783
8636148
16153721
10224053
|
PCSK9
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
22081141
29209441
17435765
25613181
23085658
18753623
18250299
|
APOB
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12031600
24447298
11986215
15840700
1132787812031600
11327878
|
HEXA
|
GM2A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
2970528
1720305
527942
16698036
2971395
|
PPARA
|
LPL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10774955
15713663
12208475
10634806
8895578
12042669
9226459
14960661
16890192
|
PPARA
|
APOC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
9209702
9226459
10494028
11007963
|
PPARA
|
ABCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16530456
17026988
12595494
20606297
20346718
19201410
18498712
18758514
|
PPARA
|
SCARB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12763030
16530456
16584836
12511553
10821819
|
PPARA
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10744771
11042130
10777541
17660447
14960721
|
PPARA
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16530456
7983038
16492688
20371549
9694537
9748239
12882972
|
PPARA
|
LPL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20813756
18391971
|
APOA1
|
ABCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
30458687
12084722
12869555
22271762
27100352
|
APOA1
|
LCAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
1587806
10222237
10026251
19860440
16189514
15654758
4335615
17676061
1644835
|
SREBF1
|
PCSK9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16407292
17921436
|
SREBF1
|
CETP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10393213
9712863
|
HEXB
|
GM2A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
2970528
1720305
527942
16698036
2971395
|