Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAPK3 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAP3K14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12049732 16691505
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
H2BC9 NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CEBPB HSPA7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11866474 11162511
GRB10 ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
H2BC9 HMGN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 HMGN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGN2 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGN2 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGN2 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGN2 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 H1-0 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H4C6 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-0 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 H1-0 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-0 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CSK ARRB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10753943 19262695
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
ELK1 MAPK3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
HSF1 HSPA7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11866474 11162511 8940068
MAPK3 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21419341
MAPK3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14993270
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
MAPK3 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 53.0 1.0 Omnipath 17081983 20166139 34363019 26359349 22768106 24516381 24126052 19413330 15302935 28618124 30138434 10747973 27639166 27997575 20068231 31614463 12917326 8940068 18669648 27105490 26340096 27605553 25752395 27487129 9121459 25406061 33461973 27354066 19651622 31657478 31940498 26010766 32959058 33268814 19664994 22172248 24954509 27791982 18212344 25024384
ELK1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 8386592 11145955 7588619 7889942
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 19327116 19443782 15212693 15367685
MAPK3 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 9130707 20506250 15547943 20371703 7618106 7601337 12697810 12473660 23331499 8007980 16291755 16393692 16998585 18988627 17255949 8208531 15014501 15187187 8586671 19541618 11145955 25241761 19565474 11309409 8887554 17052211 15277685 18334532 15782123 8548291 14499342 9927426 7889942 8262053 8386592 10716983 12665513 15967991 8477450 12947314 15212693 11274345
MAPK3 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15952796 18669648 18220336
MAPK3 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
PAK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 26598620 10330411 11096073 16717130 14580336 18986306 27542844 28214467 25472536 17440071 23317503
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
CSK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17389395 18707149 27447856 11695992 7529872 9890993 14665621
CUL1 MAP3K14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541