Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SQSTM1 BAG3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7263374 19229298
BAG3 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BAG3 SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 7263374 19229298
SMCR8 C9ORF72 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
C9ORF72 EIF2B2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SMN1 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21070772 8052760
SNX6 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HSPA8 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 REL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMD8 PSMD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
SMN1 RAB38 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBK1 REL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888014
C9ORF72 SMCR8 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 27103069
C9ORF72 SMCR8 â—¼   GTPASE_REACTION ✅ 0.81 0.81 mint 27103069
SMCR8 ULK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30669939 27103069
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RAB8B RAB8A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26824392
RPTOR BAG3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
PSMD10 PSMD8 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
ATG13 C9ORF72 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
C9ORF72 ULK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RPTOR ULK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ULK1 RPTOR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21795849 25686248 21460634 21460630
SMCR8 WDR41 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
ULK1 RB1CC1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8428476 23392225
TBKBP1 TBK1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220020 17568778
ATG101 ULK1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
ATG13 RB1CC1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
PARK2 PSMD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TBK1 TBKBP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ATG13 ATG101 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8428476 23392225
ULK1 ATG13 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26018823 21460630 32668203 27203176 33422265 19597335 33450483 23524951 33499712 23392225 32707033 21460634 18936157 25126726 32543267 29196462 25686248 20562859 27617292 30853401
RAB6A DCTN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16902405 12401177 16473624
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
TBK1 AZI2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29251827 21903422 30420664 29395067 14560022 14743216 23286385 21931555 27620379 17568778 32707033
ULK1 RB1CC1 â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 19597335
ULK1 ATG13 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 19211835
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BAG3 HSPA8 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
TOMM20 TOMM22 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
RB1CC1 ULK1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ATG13 ULK1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PSMD10 PSMD4 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
C9ORF72 WDR41 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
TANK TBK1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DCTN2 DYNC1H1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
TBK1 TANK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 31114588 30420664 23286385 18307994 23007157 21931555 17568778 32707033 30561431 10581243 29395067 14743216 21988832 17823124 25409927 24488098 16189514 29251827 27035970 21903422
C9ORF72 SMCR8 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
AZI2 TBK1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
DCTN1 DCTN2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATG101 ATG13 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
DCTN1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMA4 PSMD8 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMA4 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD4 PSMD8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATG101 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20562859 23392225 19597335
ATG101 ATG13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 20562859 23392225 26299944 19287211 24290141 19597335 24100292
SEC22B NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
SEC22B RAB1A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21532587 24917561 20966969 17287728
ULK1 AMBRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23524951 25438055 20921139
RPTOR ATG13 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11274345 11756498 12150925 12408816 12906785 15755954 16469695 17680028 18000759 18492954 19022819 19151919 19225151 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
ULK1 ATG13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15197469 19225151 21460630 18936157 27932573 19287211 19597335 27390127 27387056 27203176 25686248 26018823 20562859 23524951 33450483 26687599 19211835 23392225 26138443 25126726
ATG13 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20562859 19225151 23392225 19597335 19211835
AZI2 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 21903422 19820708 14743216 21931555 14560022
BAG3 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25036637 27474740 23824909 21233200 9873016 26496610 16189514 21423662
RAB6A DCTN2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
RAB6A DYNC1H1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
PRKAA1 ULK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24820971 23372762 28295473 21460634 19584320 21205641 21258367 28389629 34421918 34224814 25980607 32978258
PRKAA1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21460634 18439900
ULK1 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20562859 19225151 23392225 19597335 25686248 26118643 19211835
RPTOR SQSTM1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12150925 12777372 15340068 15755954 15854902 16252010 16469695 17991864 19299511 19864431 19942859 20484410 20531300 21981924 22025673 23087689 25002027 26159692 26587781 28574505
TBK1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24818040 25040165 29147513 28655770 31810986 28871090 25505069 32966780 27846364 31444413 27404485 34996837 32835772 24886973 30223576 29930914 29973599 27005665 22921120 25723488 25972374 33084718
TANK TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16127453 17568778 27035970 25409927 23286385 18307994 24488098 21419663 21988832 21903422 15210742 14743216 16189514 19820708 21931555 10581243 23007157 17823124 17468758 17327220
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368