Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PALS1 PATJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215229 11927608
PARD6A PATJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
PARD3 PATJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17235357
ABL1 CD2AP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
CDK9 ARHGAP17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SLC9A3R1 ARHGAP17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213905 11285285
CAPZB CAPZA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DCTN3 CAPZA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
CAPZA1 DCTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
CAPZA1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
DCTN3 CAPZB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
GRB2 CAPZB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
CAPZB DYNC1I2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TRIP10 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212318 10713100
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
CDC42 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10934474
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 CTTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
GRB2 TUBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
PIK3R1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220762 8246987
PRKCI PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213720 11257119
SH3KBP1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DCTN1 DCTN4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PARD6A PARD3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5213720 11257119
DCTN3 DCTN4 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CDH1 SRC â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
LAD1 ST14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EPCAM LAD1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PIK3R1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
PARD3 AMOT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16678097 34079125
RAC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
TUBB TUBB1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CAPZA1 DCTN4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
INADL PARD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17235357 34079125
MPP5 MPDZ â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24366813
ARRB2 SRC â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CDC42 CAPZB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
AMOT MPP5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM ST14 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM SPINT1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CAPZA1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ARHGAP17 SH3KBP1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
SPINT1 ST14 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CDH1 SPINT1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CDC42 PIK3R1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
TUBA1B TUBB1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SPINT1 ST14 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AMOT MPP7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 16678097 24255178
DCTN4 CAPZB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28718761 26344197
CDH1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CRK SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CD2AP SH3KBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
DCTN1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8955163 16189514
CRK PIK3R1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ABL1 PIK3R1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
AMOT MPDZ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 19615732 24255178 16678097 34079125
CAPZB DCTN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 27173435 26344197
INADL MPP5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
DCTN1 DCTN3 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
SRC ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11494128 12522270 11781820 17318191 17474147
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRK TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
DCTN4 DCTN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 28718761 26638075 28514442 34079125
DYNC1I2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
GRB2 TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
MPP5 INADL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11927608 21481793 24366813 28514442
SH3BP1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10508610 16189514 32203420
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
TUBB1 TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
GRB2 BTK â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 20936779 19380743
CAPZB DCTN4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
DCTN1 DCTN3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CD2AP GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19380743 10339567 21988832 21706016
DCTN1 DCTN4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
DCTN1 MAPRE1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDC42 PARD6A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
PARD3 PARD6A â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PARD6A PRKCI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DCTN1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CAPZA1 CAPZB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PARD3 PRKCI â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
LCK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16076903 16787943 17570479 11847100
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 12445832 15212693 12573241 8629002 17932028 10051622 25704810 8630736 34162728 9188445 16497976 20841568 27602755 11598012 9326643
ABL1 TRIP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19631450 20841568
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20861316 17306540 20841568
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
SRC BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19109164 23170196 8629002 29455639 10051622 8630736 26165234 9052864
BTK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20936779 19380743
CAPZA1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
CAPZB DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
PIK3R1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
CDC42 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CDC42 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10934474 14676191 10873802 11260256 16189514 12606577
CDH1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 19029934 22370635 16099633 23343194 19734908 10744074 16039586 22203675 19171760 22007144 19619488 17143292
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
PIK3R1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CRK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
SRC CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 27603901 22823952 7680654 9748248 28522963 19419567 19690332 16497976 15592455 19413330 25077552 17389395 19534553 20068231 28769876 17570479 20708589 19273217 18491316 18669648 16162656 25682866 12522270 18088087 22761768 26142315 17287340 27009365 10921917 9683637 24465712 27758765 24675741 12601080 18707149 16212419 15169891 7519605 17016520 11389697
DYNC1I2 DCTN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN3 DYNC1I2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN3 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DYNC1I2 DCTN4 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN4 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
LCK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8294442 11337495 8246987 14583609 11526404 15032589 23109003 9461588 7504174 8397196 10488096
PRKCI PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 14676191 22579248 27554858
PIK3R1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7629060 8034624 12086876 12515821
PRKCI SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 11713277 15567848 14585353
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929