Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ACTR3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LRP1B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SORL1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R1A CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CDK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18235225 20236090
PPP2R1A CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2CA CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTTNBP2NL STRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23015759 18782753
DAP3 MRPL45 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL28 MRPS9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL45 MRPS23 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL45 MRPS5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL45 MRPS31 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL45 MRPS24 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL45 MRPS7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL45 MRPS9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 PMAIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10807576
STRN PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
SSBP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19066201
STRN4 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
ZNF331 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22790872 20395210
MRPS24 MRPS9 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DAP3 MRPL28 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
MRPL28 MRPS23 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
MRPL28 MRPS24 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPS31 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPS5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDK1 CDC25C â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 8119945
CDC25C CDK1 â—¼   DEPHOSPHORYLATION ✅ + 0.83 0.83 Signor 19574738
MRPS5 MRPS9 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
DAP3 MRPS24 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS23 MRPS7 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS23 MRPS24 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS24 MRPS7 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
DAP3 MRPS7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PNMA2 ZNF408 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MRPL28 MRPS7 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
APP SORL1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PMAIP1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15705586
BBC3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15574335
ZNF331 C8ORF33 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 FHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18615633 11062252 22796152
ZNF331 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR4A1 ZNF331 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STRN PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29802198 10681496 18782753
SET PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9353299 21806989
ZNF331 PTK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ZNF331 SURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MRPL28 MRPL45 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
MRPS24 MRPS5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MRPS23 MRPS9 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
DAP3 MRPS7 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
MRPS24 MRPS31 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
MRPS23 MRPS5 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MRPS31 MRPS5 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
DAP3 MRPS23 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPS7 MRPS9 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MRPS31 MRPS9 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS23 MRPS31 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DAP3 MRPS31 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MRPS31 MRPS7 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MRPS5 MRPS7 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TP53 FHL2 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
CTTNBP2NL STRIP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2NL PPP2R1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2NL PPP2CA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN3 STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2NL STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2NL STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2NL STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRIP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPP2R1A STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DAP3 MRPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1A STRN3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1A STRN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
STRIP1 STRN4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DAP3 MRPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MRPS5 MRPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP1 STRN3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP1 STRN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TP53 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11278953 12203124 16931621 9582019 17693666 11118038 12433990 11395510 8183578 11429705 10400708 15242522 11423991 19067706 24336083 18381427 22732402 15988033 16341121 10935506 10094833 16215989 17280505 10744634 12851404 20673369 15851483 8845569 10559267 12168779 11850816 19505426 8564971 11756653 19054058 15566940 12173040 17690113 8635454 18034190 10510469 10101800 11335718 23100276 9400998 9445173 9582400 24098340 22532570 9122197 11420692 11104574 15679092 11748232 12560513 11928223 20400479 20546728 17145718 20567883 20840522 18172861 10566557 10777477 7834749 12806965 17521288 19242108 9000137 21859835
TP53 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14963330 16151013 7834749
TP53 BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 23916609 14665630 18397889 17390010 22763818 11463391 15988033 16462759 17280505 22948151 16151013 20190809 23678107 17989286 17360476 11756653 20331637 21835778 15790310 17440969 20478995 17047080 12384701 18657356 18755897 15489892 18579560 11463392 11572983 15007388 17610896
TP53 BBC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12574499 11463391 11463392 14634023 14684737
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDK1 CDC25C â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 1075565 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17568790 17596790 17660363 18073536 18414028 18543256 18590585 18786381 18995830 19652693 19686080 7575488 9892021
TP53 CDC25C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11396965 16582636 16807237 15574328 19861536 11972334
TP53 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18431400 29302370 16753148 16713569 10853038
CDK1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17349584 17110335 17303408 18073536 1075565 11836499 15279786 8348613 7575488 20668692 24710276 9733650 12036951 20068231 8440392 12742231 32075732 16189514 9141461 16123593 18669648 19652693 18590585 9585407 12814430 10864927 10373560 18691976 11313986 12124778 18786381 17660363 18272572 8119945 15917306 27038604 9268380 17596790 28396830 17568790 19350548 16964243 10037602 18212344 12478465 12766774
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
CDK1 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20236090
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
NR4A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23071566 17139261
TP53 PMAIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10807576 23959540 15580300 19797274 15856024 20591651 22216287 14695212 14500851 20195489 21969549 18042711 20160496 15598651
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
TP53 BAX â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368