Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CHRNA4 CBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SORL1 CBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBX1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHRNA4 EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHRNA4 SORL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHRNA4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
SORL1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 NDUFV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRPAP1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF2S2 NDUFV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SORL1 NDUFV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDUFV2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SORL1 EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF2S2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SORL1 GGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11821067 5215069
PNP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SORL1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RET GDNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
CRLF1 CNTFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21715184 10966616
SORL1 PNP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC CBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
GDNF RET â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CRLF1 CNTFR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26858303 10966616
GGA1 GGA2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
LRPAP1 SORT1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
LRPAP1 SORL1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
APP SORL1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
KAT5 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12776177 15572685 18003922 35140242 30415952 20946988
GGA1 GGA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14638859 33961781 28514442
MYC APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
PPP1CA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11039908 11551964
CRLF1 CNTFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23355913 10966616
ZNF408 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ERBB2 ERBB3 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
GGA1 SORL1 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
GGA1 SORT1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
ERBB3 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 31862538
ERBB3 ERBB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10799311 12896906 25241761 30523157 23680147 30898150 19411071 17426253 10572067 11173924 24557338 23866081 8665853 19060928 25326665 7592681 25315821 22733765 21075308 23436906 8816440 21278786 25898135 15812817 7538656 16843263 20227043 23688700 15504738 22806884 17148612 21203579 9130710
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
KAT5 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21832049 12032152 16223726 14699153 15331662 15044485
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
IL6 IL6R â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
IL6 IL6R â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
IL6 IL6R â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
IL6 IL6R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 8702737 7744001 23663276 15895091 9028955 1995637 23331499 12829785 3136546 21071413 14656210 28265003 12643274 7893704 18923185 11238858 8706672 8676083 18067990 2788034 14557255 18775332 9694899 7744875
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874
APOE SORL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11294867 11557679
ERBB2 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 23680147 17148612 24557338 19411071 21203579 7592681 23688700 23331499 21278786 12648465 22806884 27531070 17570479 30898150 29066975 17426253 16843263 9130710 20227043 25241761 10799311 8816440 22733765 10572067 19060928 11173924 21075308 23436906 7538656 15504738
GDNF RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23331499 14514671 8674117 9482105 23429478 9182803 22751117 25684228