Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SKP1 FBXW7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21620836 8177582
GTF2I KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15941713 9915861
IGF1R INSRR â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
STYX IMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 27432908
STYX F172A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28007894 27880917
STYX SKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 27432908
STYX CAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28007894 27432908
SKP1 F172A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
IGF1R ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 17307140
ERBB2 INSRR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 30898150
ERBB2 RPA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21555369 26496610
FXL12 STYX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27880917 24035498 27432908 28675297
EGFR EPHA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657067 24797263
ERBB2 EPHA2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30898150 28205554 28628118
INSRR INSR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 8916919
EPHA7 EPHA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 22036564
ERBB4 ERBB3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7689552 10572067 25315821 20227043
INSR INSRR â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
EPHA7 EPHA3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 28514442 22036564
SKP1 FBX38 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 30804394 27705803
STYX FBX38 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28007894 27880917 30804394
FBXO31 SKP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ERBB2 ERBB4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
FXL12 SKP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 18660753 32296183 26124079 23324393 27705803 31257023 27215384
STYX FBXW7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28007894 32239181 27880917 30981757
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23436906 10527633 27756321 21278786 18803307 17148612 22439932 25315821 10572067 24189400 23866081
MAPK1 GTF2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10648599
FBXL12 SKP1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ERBB2 ERBB3 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
RPA2 UNG â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ERBB4 ERBB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24557338 30898150 8816440 16767099 25315821 10572067 10839362 21203579
ERBB3 ERBB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22806884 25898135 30523157 9130710 21278786 15812817 20227043 16843263 10572067 19411071 19060928 8665853 10799311 8816440 17426253 17148612 21075308 12896906 15504738 23680147 23688700 23866081 22733765 7592681 21203579 25326665 24557338 23436906 30898150 7538656 25241761 25315821 11173924
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
FBXW7 SKP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MAPK1 TPR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12594221 18794356 22028470
STYX FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28007894 30981757 32239181
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
ERBB2 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 23680147 17148612 24557338 19411071 21203579 7592681 23688700 23331499 21278786 12648465 22806884 27531070 17570479 30898150 29066975 17426253 16843263 9130710 20227043 25241761 10799311 8816440 22733765 10572067 19060928 11173924 21075308 23436906 7538656 15504738
ERBB2 ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 10839362 8816440 24557338 16767099 21203579 10572067
MAPK1 SKP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368