Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
HSPA5 CRP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP63 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17632082 19719829
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 WNT9B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PTPN11 KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9405464 19706677
WNT7A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857724 15578921
WNT10B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
WNT9A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
MITF SERPINF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22115973
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
NFATC2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23858296 22333584
PPARG PNPLA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17848638 18189154
TP73 SERPINF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15856012 18546269
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
TP73 WNT4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16343436 20161747
SERPINF1 SGTB â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
LRP6 WNT1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
WNT7A WNT7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT3A WNT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WNT4 WNT7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LRP6 WNT3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
WNT1 LRP6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11448771 11029007
MLH1 PCNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28439008 32814904 15225546
SOX2 NCOR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 28794006 23667531 21532573
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MYC MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29467282 12584560
PPARG PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17389773 14764597 19673929
TP53 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8090761 10029407
GATA3 SERPINF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
WNT2 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23209147 15578921 32196115
WNT9B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20093360
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
TP73 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11309270 18829110 21245298
MYC WNT10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
NCOR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22395773 20462215
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
EPM2AIP1 SERPINF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NCOR1 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA MLH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
WNT3A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23400998 21078818 19339249 12897152 14739301 24265322 16890161 22726442 19910923 15578921 20093360 22491013 18772438 21944579
LRP6 WNT8B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
GATA3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 15632071 15896659
LRP6 WNT8A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18528331 15578921
WNT1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21078818 11029007 10557084 23331499 29444668 21071413 11448771 18988627
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
MYC WNT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19609274 22710352 17485441 20945354 19149881
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
PPARG NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15175761 11877444 15604093 16127449 11903058 22078880 23703729 9121466 21775429 17468099
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
TP53 FGF2 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
TP53 KDR â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
TP53 WNT3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368