Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KAT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10096020
SUMO2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO3 SENP1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 22878415 8402547
SENP1 SUMO1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 22878415 8402547
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
FHL3 SENP6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
SENP6 ZDBF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SENP6 SUMO2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
SUMO1 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 17938407 21098080 15576338
PRP19 SENP6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 29395067
PRP19 ZDBF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 29395067
SUMO1 SENP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8402547 22878415
SUMO1 SENP1 â—¼   CLEAVAGE ✅ 0.87 0.87 mint 8402547 22878415
SP1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18239466 18572193
KAT5 RUVBL2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SENP1 SUMO3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
SENP1 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SENP1 SUMO2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
KAT5 EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
SUMO2 SENP1 â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome 16253240 16608850 15487983 16738315 16738331 12192048 11896061 17591783 14563852
POLM SENP6 â—¼   KO_UP_REGULATES ✅ + 4.37 4.37 PKG 28854368