Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SUMO3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OGDH ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNF1A CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19782160 17848139
HTT DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DLD GCSH â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 Reactome 16263718 9242632
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 SIAH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 16141343
HNF1A ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11522780
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
FGFR3 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 NCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OGDH HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT NCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYLK4 OGDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
OGDH TTC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLSCR1 OGDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
OGDH OGDHL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ESR1 KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
IARS LARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
DLAT OGDH â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
DLAT PDHX â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PDHA1 PDK1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PDHX PDK1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DLAT GCSH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24256811 10103005 24341803
DLD GCSH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24256811 10103005 24341803
GCSH DLST â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24256811 10103005 24341803
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
GCSH OGDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24256811 10103005 24341803
PDHA1 GCSH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24256811 10103005 24341803
PDHX GCSH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24256811 10103005 24341803
MAPK6 PLSCR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DLAT PDHA1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
DLAT DLST â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
DLAT DLD â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
DLST OGDH â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
IARS LARS â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DLD PDHX â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
BRCA1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20016603 25218447 20016594 21147198
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
PDHA1 DLAT â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLAT PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLD PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
PDHX PDHA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHA1 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 22195962 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
PDHX PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000