Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BRAF PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
METTL13 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSE1L PPP5C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EIF2B5 KLK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
ETF1 RPS3A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPS3A HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
IPO11 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLK6 METTL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
THAP1 METTL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS10P5 RPS3A â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
EIF4A1 RPS3A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EIF4A1 RPS2 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
RPS10P5 RPS2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
GCN1L1 NAA25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
LRRK2 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
MYC AP3D1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
RPS10P5 RPS3 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MDC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TSN TSNAX â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MDC1 SMARCC1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ETF1 RPS2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RPS3 RPS3A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EIF4A1 EIF4A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
MYC IPO9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
GART PAICS â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
EIF4A1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC EIF4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
MYC PIK3C3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
RPS2 RPS3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
SMARCC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ABCE1 RPS3 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ABCF3 GCN1L1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RPS2 RPS3A â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
EEF2 RPS3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ABCE1 RPS2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
ABCE1 RPS3A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MDC1 MAPK6 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
MDC1 METTL13 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
EEF2 RPS2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPS3A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPS2 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS3A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS2 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TSN TSNAX â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GSK3A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11018017 17081983 2663470 11877389 14563837 8247524 16023596 15150404
GSK3A EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 19651622 19007248 17081983 20166139 9468292 18691976 18088087 11500362 19664994 20068231 18452278 18707149 12133000 16097034 19413330 18669648 15302935
LRRK2 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
GDI2 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
MYC GPI â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10823814 11274345 11283613 11283614 11704864 16126909 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
MYC PAICS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368