EGFR
|
NRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
KRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
HRAS
|
HSD17B12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DLD
|
BCKDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2188967
10745006
|
LRRK2
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19302196
|
FGFR3
|
HSD17B12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GSS
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6540704
18309294
|
ESR1
|
EPHB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17685427
20484412
|
ESR1
|
CHAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10037443
|
ESR1
|
CKB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17272396
10411295
|
ESR1
|
ADA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11357058
18414489
|
ESR1
|
B4GALT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14605097
|
AK2
|
ADCY5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ATP5PF
|
ATP5PD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ATP6V0A2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.81
|
STRING
|
36370105
|
CYCS
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
RHOB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
ESR1
|
CERS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
31527615
|
EZH2
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27634302
26496610
|
RHOB
|
ADCY3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
DHCR7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
DGKD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
ACSL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
BPNT1
|
CHDH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ENPP6
|
RIPK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ENPP6
|
GNPAT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BTRC
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
ESR1
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21984853
31527615
|
ESR1
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
17502350
|
EGFR
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
COX7B
|
GNMT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
GSK3B
|
MAP2K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
ILK
|
ACACA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17353931
23455922
|
GSTA2
|
GSTA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
26186194
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
28065597
20935677
11887937
17284441
|
ATP6V0C
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
COX4I2
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
ILK
|
CKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GSK3B
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ESR1
|
CYP2C19
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20675569
|
GAA
|
GYG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
5264799
3049072
8420990
|
ATP6V0C
|
ATP6V1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
DLAT
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
GSK3B
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15288510
16288047
|
HLCS
|
ACACA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
9630604
14766011
10677481
7732023
16134170
20153287
22123817
|
IDH3B
|
IDH3A
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
28514442
16713569
31515270
14681455
33961781
26186194
10601238
14555658
|
ILK
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15207235
14990992
16799642
20827300
27683053
9736715
12960424
26547035
17490631
12629168
17182785
21035499
16189514
17107957
16936772
17485554
|
GSK3B
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10428798
10949034
17609434
15461668
9528769
12118371
15059947
16076840
17570479
7491495
12093745
8308015
15212693
15528270
7838153
|
ESR1
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16972788
16010691
17511620
15858227
15837795
20716622
22837390
|