ABL1
|
BMP8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10601328
19564926
|
ABL1
|
ARHGEF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CNTFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11753601
9916993
|
ABL1
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18619508
23418320
|
GRB2
|
ACKR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
APAF1
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
5214497
11550094
|
BAX
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11709054
|
ATF2
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11413310
12388374
|
CREB5
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8378084
8440710
|
GRB2
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
BCL2L11
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
BCL2L1
|
BAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
BCL2L1
|
BAK1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
BBC3
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22492984
17289999
|
BCL2L11
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
BAX
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0912742107
20080742
|
BCL2L11
|
BAX
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
STAT5A
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14695224
14500638
|
BCL2L1
|
CREB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
CDKN2A
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19049976
|
CASP3
|
BID
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CREB1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9926942
6548521
|
JAK1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213490
11163768
|
BRCA1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18025037
16331276
|
CASP8
|
CASP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18669646
0712034105
|
CASP9
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
AKT3
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
AKT1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12011067
15573119
|
CASP3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17899380
|
CASP9
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12011067
11248093
|
CASP9
|
BIRC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11024045
5213055
|
CASP9
|
BIRC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11024045
5213055
|
CASP9
|
CASP7
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
SYK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220991
8621719
|
LYN
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220991
8621719
|
CSF1R
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
SHC1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220991
8621719
|
HCK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
CSF1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
CDH1
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0913813107
20439707
|
CCND1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16461912
0506281103
|
ATF4
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18729081
20101207
|
STAT5A
|
CD44
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16670309
23313770
|
CD44
|
ARHGEF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12748184
16189514
|
CDKN1A
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
AKT1
|
CDKN1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12244303
11231573
|
STAT5A
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15003515
21038417
|
NFIA
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17130157
|
CCNA1
|
CDKN1A
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
AR
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10076995
|
CDKN1B
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
AKT1
|
CDKN1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12244303
11231573
|
MAX
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11313917
18393360
|
CCNA1
|
CDKN1B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
CDKN2A
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
FBXW7
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11533444
5214465
|
FBXW7
|
CCNE1
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11533444
5214465
|
CCR10
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PTPN6
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10660620
6671678
|
EPO
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
CNTFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
LYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
GRB2
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
CD59
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
ARHGEF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
CBLB
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
GRB2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17993263
15031289
|
SHC1
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7516469
5220322
|
LYN
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
PTPN11
|
ANGPT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10521483
9764820
|
PTPN11
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
8766559
|
CDK6
|
CCND3
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
CREB1
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20864035
|
CALM3
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
AR
|
APPL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12621049
20610535
|
CALM1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12799359
11988487
|
AR
|
CALM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16619263
20610535
|
CALM1
|
ADCY8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16258073
10075700
|
CALM1
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
EPO
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
CCL21
|
CCR7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8383238
7851893
|
BMP10
|
ACVRL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17068149
17311849
|
CALM2
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
AR
|
AREG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23415714
20610535
|
CCND3
|
AREG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11469683
16713569
|
JAK1
|
CNTF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12707266
7852997
|
CD3E
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731413
11855827
|
SHC1
|
CSF2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10704825
5212298
|
PTPN6
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8541543
|
HCK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10329689
23109003
|
JAK1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
9670964
|
CNTFR
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
CRK
|
ARHGEF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
BCR
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8978305
21602891
|
SYK
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
10825200
|
JAK1
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8943354
18508557
|
PTPN6
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12220225
|
SOCS1
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10421843
10064597
|
AGTR1
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
JAK1
|
CNTFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12707266
7852997
|
JAK1
|
CAMK2D
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
JAK1
|
CAMK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
JAK1
|
CAMK2G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
CNTFR
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11464862
|
GSK3B
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
MAX
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11511535
10508165
|
BIRC2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17145710
12887920
|
CSF2RB
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10438956
|
CD14
|
CD36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16880211
18178856
|
CEBPA
|
CD14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
CCR7
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8409790
22922463
|
CREBBP
|
CRTC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219899
17476304
|
CREBBP
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12573436
|
HCK
|
CSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
NFIA
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8981362
11509180
|
CEBPA
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9632776
|
CD70
|
CD27
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
17237405
19062317
|
CISH
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11713228
|
BIRC3
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23070005
18485876
|
STAT5A
|
SOCS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23716134
24018353
|
CSF1R
|
HCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
CREB1
|
AGTR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11108142
24244341
|
CREB1
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17043650
16301994
|
CREB1
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16293792
22890843
|
CREB1
|
BDKRB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10842322
|
CEBPA
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
CEBPA
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
STAT5A
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16455947
12970402
|
CEBPA
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19564408
24191285
|
CEBPA
|
ELANE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
CEBPA
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15676205
|
CREB3
|
CCL15
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17296613
17192849
|
CCND3
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16609025
|
ACVR2B
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
GSK3B
|
APC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10698523
|
CD3E
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
AGT
|
ANPEP
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15687497
17803194
|
ALK
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11850821
|
STAT5A
|
JAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8709637
7489741
|
PRL
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19262752
10358079
|
ACVR2B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
BMP8B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
ACVR2A
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9748228
8612709
|
BMPR1B
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMPR1B
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMPR1A
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10712517
|
ACVR2B
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
CAMK2D
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20668654
1000426
|
BMPR1A
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
ACVR2B
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
BMP8B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
CEBPE
|
ELANE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10233885
17347301
|
CCL1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11470772
10910894
|
CCL18
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23951310
32103204
|
CCR3
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CCR6
|
CCL20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9169459
12149255
|
BDKRB2
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
AGTR1
|
CD37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CCR2
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CCR2
|
CD59
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CCL25
|
CCR9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10229797
10640743
|
CRK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
CBL
|
HCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
ATF4
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
CDKN1A
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
16765349
5218735
|
SHC1
|
CD22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
10748054
|
GSK3B
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
25241761
14536078
8861947
|
CCDC6
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BAD
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19427863
17274640
|
AXIN1
|
AXIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22682247
20128690
|
CRKL
|
SOCS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25814554
29991678
|
PTPN6
|
CD33
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
10206955
6671803
|
SOCS1
|
JAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10707961
11133764
29991678
29674694
|
CD70
|
ADCY6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SOCS2
|
SOCS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17898043
29991678
|
CKS2
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CD27
|
CD59
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
BAD
|
BCL2
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15694340
|
ACVRL1
|
BMP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
JAK1
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9346240
|
AKT1
|
GSK3B
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15829723
|
AKT1
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
23552696
|
BCL2L1
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9539746
|
SHC1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
8112292
19380743
10194451
|
CBL
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
8621719
14725908
20675402
8641358
19380743
|
CBL
|
CD38
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
18974118
19635790
|
CCND3
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
16782892
33854235
26496610
9716181
33961781
26186194
23455922
|
ATF4
|
CEBPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23661758
20102225
|
AREG
|
ADCY9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CD27
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CSF3
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16492764
10364174
|
CD27
|
ADCY9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCNA2
|
CCNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
JAK3
|
ALK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
14968112
11850821
|
CR2
|
CR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
1708808
7690834
|
AKT1
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
31575057
|
AKT1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CSF2RB
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
JAK3
|
STAT5A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
18250158
|
BRCA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CD33
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CREB5
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8440710
28514442
26186194
33961781
|
LYN
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8806683
10432313
|
LYN
|
HCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
CCNE1
|
CDK6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9716181
28628118
28205554
|
CBLB
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9614102
16189514
|
SHC1
|
ALK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11888936
33961781
16713569
9174053
|
SOCS1
|
CSF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11297560
29991678
|
CD70
|
CD27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
7479974
8186199
9862673
9767422
21917027
15723067
8120384
33961781
26186194
8580829
|
HCK
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10849448
8955135
12592324
12522270
9407116
9178913
|
CCNA2
|
CKS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
33961781
26186194
19483727
18471975
|
AR
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
AKT1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
18423396
|
ALK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
APAF1
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
AXIN2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
10911903
|
ABL1
|
JAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9774693
12130510
|
AXIN1
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
7025676
19131971
|
CASP9
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11242052
8900201
25241761
1067155
15941357
11230124
15507451
18723680
17437405
|
GSK3B
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23455922
29568061
33961781
|
CDC37
|
HCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11413142
32707033
31980649
|
CDKN1B
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
34591612
|
SHC1
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
7516469
7650013
|
CRK
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8943292
8978305
19380743
|
AKT1
|
ARNT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15833858
28628118
28205554
|
CCND1
|
CDKN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
CDK6
|
CDKN1B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
16160006
|
CD8A
|
CD8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
BAK1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
CCNA1
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
ABL1
|
HCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9407116
10849448
|
APC
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17145773
21311754
|
CASP8
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16183855
11406564
|
JAK1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
11163768
|
BRCA1
|
CCNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
9244350
10373534
|
CBL
|
CD5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23376399
9603468
|
CD44
|
CD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9117348
26686862
|
CCDC6
|
FBXW7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25885523
23108047
|
CCR3
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8642344
10733106
|
BMP7
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8006002
18070108
16189514
|
CCR4
|
CCL22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9743322
9933589
9430724
|
CCR4
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8573157
12270118
|
CRK
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8035825
9837978
9461587
9617486
19380743
10464310
23397142
|
AKT1
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10869359
25241761
28628118
28205554
|
CCL23
|
CCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9886417
9558365
10660125
|
BIRC2
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
AKT1
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
ACVR2B
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CSF2RB
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
CSF2RB
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
CCL5
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9727492
15659383
9727491
12097160
11832478
12196516
11085743
|
CASP3
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10364179
11399776
18723680
|
CCNA2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25091198
16713569
9244350
10373534
|
CASP8
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15254227
11832478
18669646
11437602
8962078
|
BIRC3
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17069460
9384571
|
AKT1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
BRAF
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27034005
31980649
17979178
33961781
27684187
|
CDC37
|
AKT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
12176997
25036637
33961781
|
CCND2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9840943
28514442
33854235
33961781
26186194
23455922
9178893
|
SOCS1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10022833
29991678
|
CD36
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
1715582
20037584
|
CCR1
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8530354
7545673
9336350
|
CRK
|
CBLB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
19380743
25814554
|
CRK
|
SOCS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10022833
25814554
|
CSF2RB
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
CCR3
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
10733106
8642344
7622448
9289016
|
CCR1
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
12270118
8530354
7545673
14637022
11116158
7622448
9115216
9289016
10910894
9336350
|
CASP8
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12887920
27810922
15069192
22274400
|
BIRC7
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
25416956
33961781
26186194
22711539
21113135
|
CREB1
|
CRTC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
BCL2
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CASP3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CDK6
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
16508017
|
LYN
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PTPN6
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ACVR2B
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ATF2
|
CREB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
ARAF
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BBC3
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CNTF
|
CNTFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CD22
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CAMK2D
|
CAMK2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CDC37
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25036637
31980649
29777862
24189400
33961781
32707033
|
BIRC5
|
CASP9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11024045
11069302
16189514
25241761
|
CDC37
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22504172
12176997
31980649
24869908
|
JAK1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11527382
8536716
|
AXIN2
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12183362
10966653
33961781
23602568
32707033
23455922
29568061
30824926
|
CBLB
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10022120
25814554
|
CASP7
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16339151
30948266
9384571
|
BCR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
BMP2
|
BMPR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CCND2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CSF1R
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
ABL1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
CBL
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
BRCA1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17352427
12024016
|
CCND1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17334399
16713569
9244350
|
BIRC2
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
17069460
9384571
11084335
19258326
11106668
|
BIRC5
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
11170436
9850056
|
BIRC7
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11024045
23563149
11084335
|
CDKN1B
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
34591612
|
CSF3R
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9824671
14557262
17001306
|
LYN
|
CD22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10748054
8647200
10228003
|
CDK6
|
CDKN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
CRKL
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15143164
8978305
10194128
9747873
|
SHC1
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9824671
14557262
17001306
|
CBLC
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
16713569
10571044
25814554
10362357
|
BIRC5
|
CASP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11024045
16189514
11170436
9850056
|
CASP7
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
16339151
9384571
11084335
33961781
15580265
19258326
|
BAK1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
BBC3
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CDK6
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CBL
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
9727492
|
BIRC3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
ACVR2A
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CCNA1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CRKL
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16443220
22286129
7493940
14604282
8978305
9820532
18835194
9710592
33961781
8524328
19823681
7926767
16955467
24412932
|
ABL1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23950177
16713569
17474147
14725908
9407116
9516488
8194526
19380743
19823681
7926767
16955467
|
ABL1
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12543778
1712671
8112292
21653319
11780146
|
ABL1
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15556646
11494134
16713569
9174058
20675402
9195915
14604282
10829062
14725908
8626543
12475393
19380743
19823681
16955467
|
AXIN1
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16199882
22682247
10228155
29045831
18786926
20128690
19131971
26496610
10811618
9734785
29713058
23277359
17510365
|
APC
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10200466
17297457
9973322
|
AXIN2
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10966653
10911903
9554852
|
BRAF
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
25241761
31980649
28628118
17979178
20130576
34017080
33961781
28205554
|
ATF2
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9511728
10777595
7843287
|
ATF2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23800081
10506225
|
BCL2L11
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22492984
12242151
|
BAX
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
15574335
20956295
23374347
17289999
|
AKT3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14766748
15642728
17525161
|
BBC3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15574335
|
CREB1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11450946
16205321
18830594
|
AR
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21310825
20610535
18196538
|
AKT1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21242970
10542266
20085797
19074868
|
CDK2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
16713569
10373534
9244350
8764100
|
CASP3
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12149654
|
AR
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22038727
20610535
23554843
|
BIRC7
|
CASP9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
25416956
11024045
11084335
11801603
|
BIRC2
|
CASP9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16701639
32296183
16189514
25416956
25241761
27197231
16339151
11084335
9545235
15069192
19153467
|
CASP9
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16701639
25241761
21988832
16339151
9545235
15069192
|
CASP9
|
LYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12586738
|
HCK
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22974441
9890970
11896602
10799548
10092522
11239464
8995358
11994282
|
PTPN6
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11157475
12176909
|
CCND1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
CDC37
|
CDK6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25036637
24292678
9150368
8666233
33961781
|
CDK2
|
CEBPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11684017
34002296
15107404
|
CDKN1A
|
ANGPT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
COL4A5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CREB1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25379405
14520699
21295542
|
AR
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
17522055
18687691
|
CREB1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
CREB3
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
FBXW7
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19956254
18559665
22388891
14536078
16818231
15364936
17646408
28209614
14739463
24298052
28850619
31152129
33288957
32051583
11533444
11565033
17298674
16338364
31868589
21070969
11565034
17434132
15980150
|
CDC42
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GRB2
|
CD22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10748054
11551923
|
JAK1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8536716
11527382
|
LYN
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9837784
22509308
8861946
|
LYN
|
CD22
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9547345
9601638
9480991
|
CASP7
|
LYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12586738
|
CDH1
|
PTPN11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
16424155
16461340
17617594
|
CDK6
|
CCND2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
16713569
28628118
10022865
28205554
11360184
30217970
33961781
23602568
11358847
9178893
|
AR
|
CDK6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
15790678
|
CALM3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
CALM3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
CALM1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
CALM1
|
CAMK2G
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10860555
20668654
|
CALM1
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
CALM2
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
CALM2
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
CREB1
|
CCL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16443828
18789903
24038085
|
CCR7
|
CCL19
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11698286
17035340
19759904
|
CCR7
|
CCL19
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11698286
17035340
19759904
|
CCL16
|
CCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCL16
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
SHC1
|
ARTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8663426
9299438
9047384
|
SHC1
|
CBLC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CD3G
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
7517665
8657103
15161916
|
JAK1
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10825200
|
CASP8
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8296476
18086677
706462200
|
PTPN6
|
SOCS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
14551136
|
CSF3R
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
7512720
|
AXIN1
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
17601533
21988832
10228155
24976009
30181396
20128690
12511557
17318191
16293724
23455922
28546513
17318175
19303846
18632848
19131971
16890161
26496610
23892894
23602568
22613765
18593713
29568061
21242974
22682247
19759537
11738041
22270359
24451375
9734785
32707033
21502811
17510365
10481074
16199882
26912724
23959799
29045831
22509369
29789528
19202075
12584189
|
APC2
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9601641
10980707
|
CSF1R
|
CSF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26235028
2408759
22483114
8355686
22153499
22902366
|
CSF1
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16492764
23331499
|
CSF1
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
AR
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18794357
20610535
|
AKT1
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19713527
8524413
23824745
16009706
29464284
20856200
19995607
16123141
20682768
27563096
14645548
15688030
22337773
11035810
17428466
18505846
15470047
14701753
16282323
|
SOCS1
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
27144517
11133764
21508344
|
CREB1
|
LEP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20484458
18787032
23056265
|
CRTC2
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26652733
20730097
|
CSF3
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
CEBPA
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11914124
11579200
8702932
|
CREB3
|
CCR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18587271
17192849
15001559
|
WSB1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AR
|
GSK3B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20127713
20610535
18687691
|
GSK3B
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15361837
15178691
14985354
|
AMHR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
14746809
16446785
|
ACVR2A
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12682303
9032295
8612709
|
ACVR2B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
17295905
16446785
|
CCR3
|
CCL11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8676064
10733106
9169459
9712872
9207005
8642344
25450766
8609214
23597562
|
EPO
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9837784
22509308
8861946
|
CCL13
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10699158
23846739
|
CCR10
|
CCL27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
CCR10
|
CCL28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
STAT5A
|
CD34
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10727459
23797738
18436865
|
ABL1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
CDK6
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
BCL2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CCND2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
CCNA2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
CCND3
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
BIRC2
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
CCND3
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
ABL1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
APC
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
CCND2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
JAK3
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
BAX
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
GRB2
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
11823423
|
CDK2
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CCND1
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
CDK2
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
GRB2
|
BCR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
5214841
11726515
|
CCL19
|
CCR7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
9153236
9507024
|
BMP4
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
AXIN2
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
BCL2L1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
CCNA2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
CCNA1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
CCND3
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CSF3
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CD3E
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
BAD
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CCNA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
AKT1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
COL4A1
|
COL4A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
CCNE2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
BAX
|
BCL2L11
|
â—¼ PROXIMITY
|
✅
|
|
0.94
|
0.94
|
mint
|
7034061
19427863
|
CCND2
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
CD3G
|
CD3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
20890284
9582308
2138083
|
CCL20
|
CCR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
10488147
10498628
9169459
9223454
9294137
|
ACVR2A
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
CALM3
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
CALM2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
CD3E
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
CBL
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
CDKN1A
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
16765349
5218735
|
GRB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
CDK2
|
CDKN1B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.95
|
0.95
|
Signor
|
17409098
|
CCNE2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
ACVR2A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CDK2
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.95
|
0.95
|
Signor
|
15964852
|
CCND3
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
CASP9
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5221774
9390557
|
AKT1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15998799
10358075
25241761
11500364
9381178
11994280
23085457
15722337
19667065
15784622
|
GRB2
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5220480
7642581
|
SHC1
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10570290
10025673
16713569
8621719
9541596
8662998
9461587
9434624
9234717
8950973
19380743
15677445
|
CBL
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
7721825
12149655
9160881
18235045
8621719
7782294
12244174
15190072
33512474
32707033
|
CBL
|
CSF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11850825
10025673
10648820
7782294
11847211
|
CCND1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9840943
28514442
8647086
33854235
8479754
26496610
33854239
33961781
23455922
21654808
9178893
|
CDK2
|
CCNE1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
19561641
|
CCNE1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
CDKN1B
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
34591612
|
CBLB
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
CSF1R
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10025673
8262059
7597091
9380408
9178909
|
SOCS1
|
CSF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10022833
11297560
29991678
|
CAMK2B
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
CCNE1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
ABL1
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
9747873
11380621
15696159
8875975
9480911
21602891
18835194
18619508
12384576
8194526
11956190
19380743
24412932
9642287
17474147
8978305
12097319
17515907
33961781
12198159
7926767
|
APC
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11166179
29045831
21118991
8638126
11251183
23602568
29568061
|
CRKL
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9162067
9129019
16982329
9590251
8621483
25814554
10907644
10608804
15107835
7545163
9092574
9195915
12244174
18835194
9311917
8524328
16503409
24886428
10657627
14604282
9820532
8662998
9461587
9851874
11399323
9344843
11157475
10204582
9660791
15556646
8978305
11553620
8626543
9988765
33961781
11263968
15358160
11133830
|
CBL
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
9129019
9416834
22974441
8621483
25814554
9178909
15581361
18835194
8943292
12393469
8524328
8683103
8662998
10962563
9461587
19380743
16289966
11792427
8626543
9988765
33961781
9617486
8626404
|
CDK6
|
CCND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15232106
16713569
10022865
24855949
17517622
33854235
11739795
14681455
24953629
11360184
33961781
10580009
17420273
21654808
11160398
9178893
19075005
|
CCNE2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
CDKN1B
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
34591612
|
CCNE2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15232106
9840943
28514442
24358021
9858585
26496610
14681455
25852190
9840927
33961781
26186194
23602568
23455922
|
CKS2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
26496610
33961781
26186194
19786724
25852190
23455922
|
SHC1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
8940013
6169950
|
BCR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
8112292
11726515
15143164
9747873
10887132
8995379
8955135
9174058
14725908
21706016
33961781
19380743
32203420
9178913
7529874
|
CRK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8810325
10962563
8662907
19380743
10970810
|
CDK6
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
8153045
21516116
|
CDK6
|
CCND3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
25416956
33854235
14681455
21516116
32296183
17517622
9716181
11360184
30217970
23602568
15232106
26264872
27107012
32707033
16782892
16713569
8114739
29997244
32814053
33961781
26186194
|
CNTF
|
CNTFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7810882
10812968
18775332
8627290
20584990
7539796
|
BMPR1A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
19804412
7261592
|
BCL2L1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CCL11
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CDK2
|
CCNA2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.97
|
0.97
|
Signor
|
10652300
|
ABL1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
11583631
5214629
|
CDKN1A
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16765349
5218735
|
BAX
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
CDK6
|
CDKN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BAK1
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CCND1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
CREB1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
CCND1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CCNA2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
APAF1
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
BMP2
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
7834748
9388232
17446862
9463381
20603619
10611223
14681455
11483855
33961781
19168699
15990872
9305851
15849194
|
BAX
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21778226
18981409
15899854
32064756
10620799
21199865
17289999
9194558
8358790
21671007
16642033
21458670
22262057
9388232
10716992
20865015
14980220
9111042
24141421
17097560
15231068
9463381
33961781
17525735
29749471
23479509
26004684
|
BBC3
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
15694340
16697956
14681455
17289999
33961781
11463392
26431330
|
BID
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
19074266
11583631
9727491
9463381
15520201
14681455
17289999
18835031
12624108
|
CCNA2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
8475101
28514442
16431923
33854235
11940657
10559988
15189033
17361108
16290148
14681455
17254966
8662825
25852190
15557281
23455922
19483727
18471975
11141566
10924145
15828833
21241890
19631451
11377199
18177895
8684460
26496610
9716181
12853968
11907280
23602568
9724724
15647383
14656438
19773423
12941338
15239650
24302728
25669885
15890360
7630397
8756328
8397207
21447625
22231403
20733051
9660939
24358021
12044161
33422522
11983168
33961781
26186194
7553852
16209941
12244298
9380407
8463339
15455144
10930425
|
CDK2
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
28137908
16431923
29439025
9891079
18559665
33854235
11940657
15004009
17431037
17361108
33854239
14681455
17254967
8867812
23853094
10827081
10330164
8662825
25852190
15557281
9192873
23455922
21092281
14536078
21372285
21241890
19631451
16223725
26496610
1388288
9716181
9472014
15980415
14701826
23602568
8978686
11433299
11132966
24771265
12839982
20587660
19470470
10359664
15514162
17970072
9840943
25728284
9660939
8647086
24358021
7799941
12529437
8756624
33961781
15670215
26186194
20837141
12800980
|
SHC1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
12485888
21725358
31980649
9126968
7514169
7744881
8235613
11453982
8662733
8491186
7629070
8940013
10570290
8112292
12213123
11302736
8662998
8195171
7597091
8810340
32062451
9129019
16371368
12149229
10049786
8626525
7650032
8950973
9488479
24189400
15812354
12441060
19380743
26551075
22057045
10477741
28690151
16713569
7516467
9733714
11827484
11964172
7537740
16520382
9019162
8663178
9797459
9032244
12577067
9927207
7524086
8995379
9886492
8294403
7559490
9434624
11792427
7798267
8621719
9541596
15688026
12898421
33961781
11370743
25416956
9544989
22974441
8939605
21706016
9083103
7535773
11505033
9175774
24430869
10080542
9020193
9045692
10356320
15888547
9254595
8561895
11707405
8647288
|
CBLB
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21900206
28514442
16189514
25416956
31980649
12577067
31467278
26264872
10022120
9614102
29997244
21706016
32814053
33961781
20936779
10086340
27107012
|
CCNE1
|
FBXW7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CBL
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ABL1
|
CRK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
ABL1
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
ABL1
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
HCK
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
18775435
9407116
12522270
16787943
28087699
11847100
26473374
16912036
16076903
20841568
24708674
10849448
|
LYN
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12644574
16787943
16912036
16076903
11847100
|
BRCA1
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12919958
12024016
17352427
|
ABL1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
100.0
|
1.0
|
Omnipath
|
8978305
9747873
9480991
19426560
17081983
23124138
16522685
16713569
20841568
18768933
8875975
25860930
21779437
19534553
16187300
17515907
21602891
16267043
20068231
10592173
17570479
8194526
7926767
11080615
25381819
12198159
9642287
15696159
18619508
18835194
11956190
22848689
11314030
9480911
19001122
19402756
20697350
12384576
24412932
7542925
11380621
12799422
19380743
12955086
17474147
17016520
|
ABL1
|
BCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9407116
10405761
12522270
11780146
8622703
9178913
1712671
12124177
7529874
9467953
8955135
20841568
8112292
16912036
12543778
11376433
|
ABL1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
22553782
24974292
29066624
15657060
20841568
28177918
|
ABL1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
9525940
11494134
16713569
20841568
10829062
17389395
16955467
12604776
9890970
10391678
9195915
14725908
7925293
11997497
12522270
15556646
9102067
11239464
11994282
9174058
12475393
20675402
19380743
14604282
8626543
15212693
19823681
|
ABL1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
8978305
22581121
20841568
10837221
18768933
7493940
9710592
16955467
8524328
23331499
21199784
18794134
10592173
21051857
7926767
16443220
18835194
24165979
26500649
18809728
15459660
26192618
24412932
9053848
22286129
8083188
14604282
21435002
9820532
19823681
|
ABL1
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
8692915
8696915
14699166
12468540
10574931
7512963
16497976
20841568
14757045
8114715
10488096
|
ABL1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17254966
17908796
22276948
16195327
|
ABL1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
11726515
16713569
20841568
8596638
16955467
10592173
8647802
8194526
7926767
14725908
23950177
8112292
9407116
23181695
19380743
17474147
9516488
19823681
|
ABL1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24836440
8940193
20841568
|
ABL1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8617726
1623525
10194451
19380743
10592173
20841568
8112292
|
CASP3
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12874265
21827945
11550094
|
BCL2L1
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
10811864
9488720
12963020
9539746
|
APAF1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
17145710
15829969
15024710
9390557
19494828
11113115
10617566
9539746
10364241
10722681
27476169
21060833
19118655
20829884
16977332
10329646
15210107
10393175
16352606
11242052
14555243
10376594
12773388
10206961
19337385
10428850
9488720
19788417
15262985
9922454
21827945
10749135
9651578
19698783
12792650
9837928
11227497
|
APC
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
APC
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
GSK3B
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
16944320
11166179
16799642
11967263
14663202
8524413
12554650
8638126
17910481
15327768
10581160
11487578
17318175
15465828
10228155
15020233
10421629
10698523
9832503
|
AXIN1
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16199882
20128690
19131971
11297546
9554852
22682247
10228155
26496610
23277359
10811618
9734785
|
ATF2
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11274345
12738796
18039929
20506250
|
ATF2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9990041
10915780
11850817
11410592
11739785
15691880
16405968
10464245
10500157
15314161
10066798
|
BCL2
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
BCL2
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
AKT1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
AKT1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
137.0
|
1.0
|
Omnipath
|
10880354
19052636
21506126
20028971
21303971
20214616
11994280
8929531
17570479
12832477
17555943
25241761
11715018
18636226
21998731
9812896
17680028
11500364
18385666
18707149
10201527
18218901
11983683
10490655
19030972
19667065
11756412
11020382
16931767
18372248
15808505
20138985
18046313
18669648
19121340
19703413
11714830
10949026
15972258
16341064
10358075
23085457
18220336
10516287
12897128
9580112
9651683
11923280
9346240
16697215
19690332
11493700
15452053
12040186
10826997
12175651
15722337
14737178
11882383
15226424
10521512
15023346
15784622
17052453
16044149
16403219
12444011
20166139
20398329
9381178
11544290
15037618
12767520
15280015
10230394
10558990
15998799
10082559
11577096
10837486
15169778
10611223
23109003
12954615
22094462
11438654
11312610
11254732
21540285
10383455
19664994
10722653
20832730
18570873
10926925
17270021
|
BAD
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
9305851
17145710
11483855
16697956
9463381
15694340
15849194
20603619
15990872
11583631
8929531
7834748
9388232
17446862
19168699
|
BAD
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
9305851
22705850
9389483
11483855
16697956
19667065
18628207
11907096
25416956
10620799
31467278
32814053
20837658
9388232
11077446
21988832
26871637
11206074
8929531
16189514
7834748
19427857
12115603
11494146
26186194
15694340
25241761
23109003
20603619
32296183
15705582
15131699
29997244
9372935
11583631
31515488
9824152
|
BCL2
|
BAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BID
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
23782464
17289999
11175253
10950869
12624108
23604079
12242151
|
BCL2
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
9463381
14980220
11206074
17289999
26004684
11728179
20836993
19168699
|
BCL2L1
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
22705850
9463381
22516262
31467278
32814053
9020082
23680104
34098062
18178565
15901672
16189514
17446862
20836993
23055042
19060904
17289999
32296183
10085290
14596824
15292519
29997244
31515488
11175750
9027312
|
BAK1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15901672
11571294
16189514
16439990
|
BCL2
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2L11
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10198631
12419244
15486085
15724238
23430059
23850759
9430630
|
BID
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20956295
17289999
25241761
19968986
15574335
10629050
19062087
10949027
12242151
23374347
14730312
17520191
8918887
|
AKT1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
26763134
14766748
15642728
17525161
|
BCL2L1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
59.0
|
1.0
|
Omnipath
|
22705850
18981409
21458670
28202514
11283018
17525735
29749471
21567405
9388232
18547146
19074440
16151013
21199865
18178565
26496610
16189514
15486085
26186194
17289999
9111042
12419244
25241761
14963330
12853473
9742125
9153240
19427863
21852238
14766748
21671007
15131699
9670005
8596636
24814347
9824152
9027312
|
BCL2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
22705850
18981409
9463381
21458670
17097560
17525735
8358790
10620799
26004684
29749471
9388232
21199865
17525161
22262057
21778226
15486085
17289999
9111042
12419244
9194558
15231068
10716992
8183370
14980220
9115213
21671007
16642033
23479509
10677502
|
BCL2L11
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22492984
26186194
17289999
12419244
11301022
12198137
17525735
21199865
18948948
23235460
11997495
15486085
12242151
23374347
19427863
15721256
|
GSK3B
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
29379583
27762303
15525785
20976235
26287183
17911107
16709574
|
BCL2
|
BBC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BBC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BBC3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
19074266
28202514
15574335
|
BBC3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
11463392
|
BCL2
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10198631
11704864
15486085
15724238
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9430630
|
BCL2
|
BCL2L11
|
â—¼ PROTEIN_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10198631
11704864
15486085
15724238
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9430630
|
BCL2
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11463391
11463392
11532940
11704864
12566895
12667443
14764585
15516985
17446862
19289794
19565474
22039431
23064052
23377657
23430059
23850759
24027568
8929532
9069260
9872359
|
CEBPA
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16254192
18987666
23814099
15713621
12970736
|
AR
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17655826
11567031
23160675
20610535
|
CASP3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10409669
9395403
20139069
11948397
|
BCL2L1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18835031
14980220
26186194
11583631
|
AKT1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
BCL2L11
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
17145710
9463381
16697956
9430630
17074758
17097560
19805519
18498746
26004684
14517273
10198631
21199865
20836993
26186194
15694340
17289999
17692808
11301022
23845444
21671007
9731710
|
CREBBP
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9829964
10753867
17565603
15337521
10454566
|
AKT3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
BCL2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16183855
11406564
|
BCL2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
18835031
17145710
9463381
16697956
17289999
19074266
12624108
11583631
9727491
15520201
8918887
|
STAT5A
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10979976
10428780
20585448
10727459
12946994
10435632
11731240
10428030
10964754
15545372
19339209
11756417
16214938
15626738
|
STAT5A
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10428780
19211554
10652277
11085453
10435632
10428030
11756417
|
AKT1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
BCL2L11
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
17145710
16697956
9430630
17525735
22516262
18498746
10198631
21199865
20836993
26186194
15694340
17289999
27013495
32296183
23245996
11859372
19427863
21671007
14596824
9731710
16260615
|
BID
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
9727492
19074440
16697956
15694340
17289999
25241761
22464442
14963330
16189514
27159560
24814347
15574335
|
BCL2L1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
25241761
9539746
|
CISH
|
BCL2L11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
AKT1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17145710
16282323
30923040
|
CASP3
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
11085742
11085743
|
CASP8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
12196516
18458084
9727491
11085742
11085743
12097160
9873064
|
CREB1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9528858
19882681
18160048
23447579
11704836
|
BRCA1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9926942
11394910
10196224
18025037
21245169
16735508
12647291
|
CDK2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8764100
10373534
10550055
19683496
16713569
26719576
15212693
|
AKT1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17428466
20832017
20085797
21242970
17570479
10542266
|
BRCA1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11085509
16713569
11016951
|
BRCA1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11877377
21060331
19793801
21337561
15459660
20029420
|
BIRC7
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23563149
11024045
17145710
11084335
|
BIRC3
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9990849
12042762
9384571
17069460
|
BIRC2
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
9990849
12042762
9384571
17069460
11382748
11106668
16189514
11084335
|
CASP8
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
15755874
17179148
9501089
9950028
18669646
23308069
10988287
18458084
16964285
9885230
9765224
11437602
15014070
21295084
8962078
9208847
|
BIRC5
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
9384571
11024045
9850056
10587640
16189514
16540654
|
CASP9
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10708865
9390557
10508159
11230124
18723680
15657060
16977332
15507451
1067155
9708736
25241761
8900201
11242052
9765224
17437405
19788417
9812896
12620238
15941357
12181739
19465923
12792650
15725726
|
CASP3
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
8626669
9535906
16713569
9208847
|
CASP3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
25241761
9660939
10022118
9799125
|
CASP3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17544405
12124386
10579725
|
CASP7
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
16916640
9922454
11752425
11701129
12824163
|
BIRC5
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
11069302
25241761
11024045
16189514
12773388
10329646
15210107
|
BIRC7
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17145710
11024045
11801603
25416956
31515488
32296183
11084335
|
AKT1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20398329
18372248
15004527
15808505
20138985
20214616
15703181
17570479
28177918
18840507
15169778
11714830
10949026
16341064
11715018
18636226
10529400
9812896
17680028
19440551
10722653
20832730
18570873
17052453
|
AKT3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9812896
|
BIRC3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
16339151
21988832
9990849
15069192
25241761
9545235
16701639
|
BIRC2
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
16339151
9990849
15069192
25241761
19153467
9545235
25416956
31515488
16189514
32296183
16701639
11084335
|
CASP9
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17899380
9922454
16352606
9598997
9651578
|
CRK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
CRKL
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CBL
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16849543
16969069
16953218
17699773
17372273
17712310
|
GRB2
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
31980649
8649804
8995445
25036637
23799367
11997436
8943292
9242692
10570290
8662998
11399323
10086340
7642581
9108392
20936779
11133830
8626404
17094785
8063801
9129019
8900205
15210722
8621483
25872741
25814554
9178909
16906159
8950973
17971399
10025673
9295052
19380743
9716598
16713569
11964172
9234717
8083187
7537740
8824292
9259313
9311917
7791764
17072306
14725908
33627783
9461587
9434624
9851874
8695851
12839496
17944804
11792427
10204582
8621719
11823423
9541596
33961781
169092
11263968
98621719
28514442
18273061
7592693
9174058
21706016
8995358
9872323
9233773
9367879
7544353
12941616
10829062
20124286
917890
15677445
9092538
10521482
8647120
19836242
|
CRKL
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRK
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
GRB2
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10086337
10426994
10567412
10811803
10982827
11447289
11777939
11777960
11907067
12175651
12640133
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
26552706
8551221
|
CRKL
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
8683103
16289966
8626543
8621483
9617486
16713569
9416834
8524328
10962563
8626404
9367879
8662998
12393469
11792427
15581361
9013636
15581362
9178909
9988765
18835194
8943292
20697350
9129019
19380743
25814554
9461587
|
SYK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
72.0
|
1.0
|
Omnipath
|
16289966
15922744
9525940
19419964
11133830
33512474
18273061
10829062
10799548
10540342
10934191
7721825
12435267
11331248
12604776
9890970
11042121
10092522
11997497
12522270
9857068
9988765
15556646
11742985
15536084
8621719
9102067
22880054
10551821
11239464
10617633
11994282
10570266
12881521
9535867
15577829
|
HCK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
10092522
11994282
9525940
8995358
12604776
9890970
11896602
10799548
11239464
10934191
|
CBL
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
158.0
|
1.0
|
Omnipath
|
11823423
8621483
9242692
18273061
17635922
16906159
8626404
8662998
9108392
9541596
98621719
9295052
25872741
17372273
8824292
8943292
12941616
20124286
19531499
10086340
8063801
9129019
9590251
11263968
9461587
7642581
10521482
10204582
8995445
8900205
7592693
9716598
8083187
14725908
17904548
7791764
9178909
25036637
8695851
19836242
7537740
15210722
9108316
169092
9311917
10514377
9092538
17072306
19380743
9872323
9234717
11997436
23799367
9434624
16713569
10829062
9367879
11964172
12839496
15677445
9851874
11792427
17094785
20936779
10570290
917890
17944804
25814554
17971399
11133830
8950973
21706016
8995358
9233773
10025673
8621719
11399323
9259313
9174058
8649804
|
CBL
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11847211
10025673
10648820
11850825
7782294
|
CBL
|
LYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12149655
18235045
12244174
8627181
8621719
7782294
15304502
9160881
15190072
7721825
|
STAT5A
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16155412
18927468
21719533
20372799
23223023
15885880
10064602
23504816
14645506
18024957
19426693
|
CREB1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
23447091
16503642
18957421
9990041
12504100
10915780
15116100
22271686
14764597
16522741
18713830
24065533
10201372
22751440
18988190
12391146
|
CDKN1B
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17145710
9106657
10908655
17254966
25416956
7478582
|
GSK3B
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
87.0
|
1.0
|
Omnipath
|
26907733
16944320
27546592
11967263
14663202
8524413
16504004
29969496
19767775
21347341
25142862
11311237
30736789
14597415
25591548
19645770
10385618
20548028
10766840
10929713
23565238
16039586
17570479
18818515
18167338
12615961
12413951
17046823
19071090
18598945
15465828
19374252
26121043
26432751
18319725
12969793
23733133
22922870
24134204
10486203
12459251
15020233
18769147
10910956
11152665
21317297
20537194
22099186
18328826
11124803
17070615
19757160
22470469
23552696
16732330
27695879
29554905
16103118
15075324
14536078
9832503
28090171
|
CDKN1A
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
26203195
23443559
17145710
25416956
7478582
9837900
21988832
21516116
7777546
15232106
16082198
27107012
15695403
8657154
8242751
23007395
9106657
12383116
17556661
8756624
8662825
31515488
|
MAX
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8425218
15121849
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
CCND1
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19075005
17517622
9178893
11739795
24855949
15232106
16713569
11360184
10580009
11160398
|
COL1A1
|
CD44
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1730778
16189514
|
COL1A2
|
CD44
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
1730778
|
SHC1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
16187797
15284455
17646646
16969069
17372273
17712310
|
CCNE1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CCNA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CCNA1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16189514
15583032
25241761
16777603
10559988
14681455
9636170
16159883
9041194
10652300
8565853
12970441
14701826
8397206
14681231
11264176
8397207
15601848
12191604
12190313
7799941
19423708
12800980
16009130
|
CDK2
|
FZR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10323868
10375532
16582612
12730199
|
CDK2
|
CDKN2A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
AKT1
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18354084
29665367
|
CDK2
|
CCDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17570479
14712216
|
CDK2
|
FZR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
11598127
15577895
9736735
12560341
15558010
20068231
10548110
16123593
15840442
18669648
|
CDK2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
94.0
|
1.0
|
Omnipath
|
23443559
23455922
10878006
20100570
23602568
15964852
20839231
25416956
23737759
9840943
18850315
11302688
20519948
24358021
19440234
15557281
9472014
9658399
16962592
9736735
12949733
8641969
10022118
15890360
12839982
16765349
17418410
15647383
10874474
15232106
17570479
17698606
12361598
26496610
9632134
24419005
12417722
16189514
26186194
20587660
25241761
8622677
9660939
25483090
12800980
20102411
10918595
12058028
12144826
8242751
9464540
9858587
29899857
23007395
11477082
9218599
12383116
25463440
12730199
8756624
9284049
9380407
9546435
24218572
16964243
15212693
13678583
|
CDK2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
81.0
|
1.0
|
Omnipath
|
8756328
7553852
11377199
17145710
23602568
11983168
12044161
19483727
12853968
16209941
8397207
15455144
19631451
8475101
24358021
15557281
8684460
12941338
15647383
15890360
21447625
9380407
26496610
11141566
25852190
15189033
14656438
20733051
21241890
10652300
25669885
12244298
26186194
10930425
9660939
10477583
24302728
15239650
19773423
8463339
16290148
10924145
11907280
17361108
17254966
8662825
15828833
18471975
9724724
7630397
10559988
9716181
11940657
23455922
|
CDK2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
125.0
|
1.0
|
Omnipath
|
26416244
20519948
19631451
16326706
17409098
15557281
9658399
23029392
22733130
17570479
26496610
23576547
12700233
9388487
10585280
27282251
27175940
15619620
25241761
15735731
9218599
9192873
17254966
15996662
9724724
11940657
18285702
22492278
23409140
18615582
12093740
22721951
15647383
9380407
17418410
16189514
17053782
17698606
25852190
10679394
17602833
9660939
12188931
15122251
10831586
25818643
22028818
21424700
12529437
15011833
12042314
11250701
11223033
23455922
8978686
16780593
21439954
15302935
19648963
14504289
9736735
10198259
16782892
11565035
21423803
16492801
9311993
12417722
17671428
21187893
15355997
28601655
10809788
10393546
15212693
10323868
26450989
23602568
18850315
12482975
9399644
15890360
9632134
17254967
26186194
20810788
20197382
15475007
12800980
17997402
12972555
15980415
24336329
26701207
25605247
26987798
|
CDK2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
17145710
16223725
21092281
15004009
10962581
9840943
8643455
24358021
8861947
21372285
17570479
11237742
10330164
22558078
10652300
19561641
10477583
18691976
23853094
12144826
10500095
1388288
10827081
17970072
28137908
19470470
8756624
10809788
14536078
15364936
|
CDKN1A
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
14517297
17092340
9106657
18710949
24515438
20843055
|
CEBPA
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15466360
9442037
12502863
8846917
|
AR
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16281084
10076995
11606392
10606230
20610535
10809237
|
AKT3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12851486
15023346
19216069
17680028
11756412
16680151
20214616
11463845
23109003
20452955
9829964
20398329
17646672
10217147
|
CDK6
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
25121590
20102411
15964852
22375140
15232106
16713569
16508017
19440234
|
AKT1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20452955
27603133
20398329
18372248
15001356
15808505
10217147
19440234
20138985
12431783
10753973
17855660
19216069
28358423
20214616
11463845
9829964
17570479
17646672
16680151
11231573
15169778
12851486
31575057
25241761
23109003
21933447
10949026
16775416
23886938
26436589
16288292
11715018
16055744
18636226
15023346
9812896
12042314
17680028
24848107
16982699
11779850
10722653
20832730
18570873
20307683
34069970
17052453
15798220
|
GSK3B
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
22154077
28916781
12058028
11779850
17570479
20519948
15212693
17283049
19440234
|
CDKN1A
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
23443559
26186194
25241761
27107012
8756624
15169570
25416956
16765349
31515488
16189514
32296183
|
CDKN1A
|
CCNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12383116
25241761
8756624
29997244
16982699
7478582
10022926
32814053
15232106
16009130
16189514
|
CDKN1A
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
21988832
23443559
26186194
25241761
27107012
8756624
25416956
16328436
31515488
16189514
15232106
32296183
23880157
26496610
9716181
|
CDKN1A
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
23443559
26186194
21308745
9660939
8756624
15890360
9380407
8242751
8662825
12947099
9632134
17679094
26496610
|
CDKN1A
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17145710
23443559
26186194
28514442
9840927
9840943
15232106
26496610
24358021
|
CDKN1A
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17145710
23443559
31831640
21988832
9472014
17293600
11438644
9380407
12839982
16765349
9632134
25241761
8891332
9660939
8242751
9218599
11477082
8756624
8662825
8637717
9716181
13678583
|
CCNE1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
31831640
8978686
8684460
17293600
9632134
17254967
9311993
20837141
27175940
9488039
25241761
8891332
9660939
7753174
19470470
9218599
12529437
9192873
8756624
17254966
12501191
9891079
10393546
9716181
11940657
|
CDK6
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16160006
25241761
18615582
16782892
21439954
11360184
|
CCNE2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17254966
9840927
9858585
9840943
|
LYN
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17145710
17254966
21423214
17254967
20966355
33147476
|
AKT1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
69.0
|
1.0
|
Omnipath
|
22119715
11756412
16780593
11923280
16697215
16209941
12244303
20398329
18372248
14967450
18710949
15808505
26053093
20138985
14504289
20214616
12244302
17570479
18593906
23576547
23400686
12851486
15169778
24651496
19829074
25241761
10949026
16288292
11715018
18636226
19377290
9812896
12042314
17680028
10722653
20832730
18570873
12244301
17052453
|
CDKN1B
|
CCNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15583032
29997244
7478582
10022926
18692475
32814053
16189514
|
CDKN1B
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
25910212
16189514
|
CDKN1B
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
8684460
26186194
9660939
17254966
15890360
16209941
12947099
12501191
26496610
9724724
9311993
9716181
|
CDKN1B
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17254966
9840927
9858585
9840943
|
CDKN1B
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
14597415
16189514
10342870
16328436
|
CDKN1B
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
17145710
31831640
8978686
8684460
17293600
9632134
17254967
9311993
20837141
27175940
9488039
25241761
8891332
9660939
7753174
19470470
9218599
12529437
9192873
8756624
17254966
12501191
9891079
10393546
9716181
11940657
|
CDKN2A
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
32284348
19273602
32601262
10821856
28985506
33043019
31597407
|
CDKN2A
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
17881001
26186194
23602568
9751050
11739795
11556834
9380698
15232106
16713569
17955473
10491434
16915296
17909018
|
FBXW7
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
12824889
11565034
17646408
17298674
11565033
19956254
18559665
17434132
22388891
28209614
11533444
15980150
16338364
16818231
21070969
24298052
14536078
15364936
|
SYK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
STAT5A
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
Reactome
|
16627759
22411868
11090077
26515730
20111072
15498859
10698507
12468433
12796379
30552988
23103841
31066629
15003515
17356133
|
GRB2
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
48.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14764585
15169888
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
9510155
|
GRB2
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
ANGPT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
GRB2
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
GRB2
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
GRB2
|
SYK
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
ANGPT1
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
GRB2
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
BRAF
|
â—¼ SHARES_COMPLEX
|
|
|
48.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14764585
15169888
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
9510155
|
GRB2
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
PTPN11
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10358138
11447289
11572860
12138178
12707331
15240681
15699106
15713798
19833085
9751747
|
GRB2
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
GRB2
|
ANGPT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
SHC1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
198.0
|
1.0
|
Omnipath
|
8808684
9083103
8551221
9126968
8621483
25416956
9252386
8524223
7535773
8662998
11302736
11827484
8995379
9541596
9175774
10207047
7717978
17673906
7744881
11505033
10523831
24189400
9927207
7650032
8810340
9045692
23178716
19531499
15812354
9129019
10356320
12485888
9461587
8114695
7514169
9566877
8939605
16371368
15341520
7529871
10891441
10749687
7524086
26645482
8491186
10592173
10049786
9171350
11707404
7537740
15688026
8663178
19380743
11782427
9544989
16436051
9434624
16713569
21725358
11964172
17314098
11792427
8195171
1465135
12213123
8647288
12955078
10477741
11707405
12577067
9199344
10080542
8112292
7760801
10570290
11997181
7798267
16520382
10961885
8950973
21706016
9448048
8662733
11370743
8051109
9733714
8621475
9254595
8294403
10748054
8621719
8940013
12441060
22057045
7505797
24737791
20697350
9886492
18174162
18273058
8235613
7963520
7523859
|
CBLB
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
10022120
25416956
21706016
31467278
32814053
9614102
17635922
11375397
8626404
16189514
21900206
20936779
27107012
12577067
10514377
19531499
10086340
29997244
|
CSF1R
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9178909
9380408
10025673
8262059
|
SYK
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11964172
16189514
22267732
10747947
|
PTPN11
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
8702859
9361008
16371368
21706016
8041791
11085989
8978300
11432792
15882975
9362449
10212213
11684012
7523381
10592173
16189514
10747947
10973965
9632781
8959326
11602579
12577067
9254654
10080542
15010462
31585087
12531430
8995399
19380743
7522233
9804835
7534299
9824671
9660791
|
EPO
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
9334184
9974393
9774108
9573010
11231127
2163696
|
LYN
|
CSF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
LYN
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
LYN
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
LYN
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11413148
17081983
7925280
11641791
9573010
15212693
8617237
|
LYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
9820500
24129562
10022120
18818202
21469132
24607955
18083107
17389395
19285079
11536198
10592173
25045209
7797565
11380624
9857068
7513017
30923129
8621719
10477689
7831290
15701717
27258042
19369195
28082678
8666899
9535867
8657103
14871838
|
LYN
|
CD22
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17145710
32323266
10228003
8647200
9586639
|
LYN
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23109003
7650013
7516469
10329689
|
LYN
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7636265
10672044
7722458
9973406
11823534
10329850
|
LYN
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
19171907
11042209
8692915
14699166
22624718
19690332
12468540
10574931
17570479
18083107
14757045
8114715
10488096
28811476
|
PTPN11
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
42.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
12176909
1238444
12393695
12421919
12707331
12773515
12917349
15169881
15240681
15699106
15713798
16204085
17371980
19833085
20007250
20038811
20363967
20435894
21469115
22437870
22483603
22513334
22683124
22952938
22955274
23732914
25355530
26667266
26755705
26885856
27474009
27806234
28893624
8976179
8986721
9751747
9765283
|
PTPN11
|
PTPN6
|
â—¼ SHARES_COMPLEX
|
|
|
42.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
12176909
1238444
12393695
12421919
12707331
12773515
12917349
15169881
15240681
15699106
15713798
16204085
17371980
19833085
20007250
20038811
20363967
20435894
21469115
22437870
22483603
22513334
22683124
22952938
22955274
23732914
25355530
26667266
26755705
26885856
27474009
27806234
28893624
8976179
8986721
9751747
9765283
|
CD3G
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3E
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
JAK1
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
8790359
21071413
8995399
12270932
12403768
9794795
11036942
|
ALK
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18320059
19223540
15710330
12522270
12531430
11684012
34301842
8041791
12721296
17483340
32076487
|
PTPN11
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
18322230
9254654
9162089
|
PTPN11
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
10617656
18508557
12220225
16189514
12060651
12237455
|
ATF4
|
CREB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17669268
17434604
18441292
15240803
15888447
16121183
|
ATF4
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11564156
9295363
25241761
|
CDKN2B
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
26186194
26578655
23602568
25416956
32296183
|
GSK3B
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
11152665
20537194
10385618
11124803
12969793
19757160
16732330
10486203
16039586
14536078
18167338
12459251
12615961
|
CCND3
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17517622
8114739
26186194
27107012
23602568
10477583
16782892
21516116
25416956
29997244
31515488
32814053
15232106
32296183
11360184
16713569
9716181
|
CCND2
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10477583
17517622
16713569
|
CCL7
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
14991608
12381680
9115216
10699158
11994538
7545673
22633458
9336350
8530354
|
CCL7
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8642344
10733106
10699158
22633458
|
CCL7
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9276730
22633458
9115216
10699158
9346309
9195948
9312096
12554737
9336350
7759884
8530354
|
CCL7
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
9364936
|
AXIN2
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15611123
10966653
10911903
888800000547
9554852
22745173
9566905
22322943
|
BMP7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9748228
7790373
12667445
|
BMP7
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11282024
8006002
31619522
122976748006002
16189514
12297674
|
BMP7
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15621726
106311828605097
8605097
10631182
|
BMP7
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9748228
23331499
16446785
|
BMP7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16189514
7791754
12297674
8605097
|
AKT1
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25241761
10490823
25814554
12621049
|
CALM1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
22944912
21299499
21730051
9199170
|
CRK
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
SHC1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRK
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
SHC1
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRK
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
BCR
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26500649
8978305
15143164
|
CD14
|
CCL3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
CCL3
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
11170631
10734056
10488147
10699158
7545673
10202040
22633458
10498628
9169459
9336350
10910894
8530354
23765404
9687537
9207005
20219869
9115216
9624164
10660125
7622448
12381680
|
CCL3
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8573157
|
CCL3
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24218476
7594543
7622448
|
CCL21
|
CCR7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11970971
10488147
9507024
10699158
16713569
22633458
22221265
9585422
|
BMP10
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17068149
|
BMP10
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
30246251
30246252
27252362
31127068
|
BMP10
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15621726
31127068
16049014
|
CCL4
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
7594543
12381680
10699158
7545673
10910894
8530354
|
CCL4
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7622448
|
CCL19
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
|
CCL19
|
CCR7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10512740
9507024
15546958
10699158
9153236
24218476
22633458
11342595
16904643
|
CCL22
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9933589
9430724
29637711
10699158
22633458
9743322
|
CCL17
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10498628
10488147
9169459
9430724
29637711
10699158
9169480
10540332
22633458
|
CCL5
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8573157
12270118
|
CNTF
|
CNTFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
23331499
10812968
18775332
20584990
7810882
8627290
8081242
7539796
10966616
|
CCL16
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11470772
22633458
10910894
|
SHC1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
SHC1
|
ANGPT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
SHC1
|
ALK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15226403
18097461
16878150
17274988
16317043
11121404
|
SHC1
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
SHC1
|
ANGPT1
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
SHC1
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
SHC1
|
SYK
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
SHC1
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
SHC1
|
ANGPT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
CBLB
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19531499
11375397
16189514
9614102
12577067
|
SYK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
19901323
9388490
9096689
16497976
15592455
9121430
10891441
17389395
11687594
10482988
20068231
10592173
9685404
9927207
15688026
7896829
9199344
9710204
17016520
11075717
|
ALK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
12185581
16713569
9174053
|
CSF2RB
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10704825
8647804
10477722
|
CBLB
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
8626404
19380743
12697763
25814554
|
CD3G
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
8226994
18818202
8862523
8340414
7522622
7530449
9314552
|
SYK
|
CD36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10358164
11907067
12524384
14568985
15536084
17101731
19909365
20150200015
21149606
21378271
21910624
23609447
23896411
8189062
8226994
9000133
9295024
9314552
9396765
9632805
9763615
|
SYK
|
CD36
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10358164
11907067
12524384
14568985
15536084
17101731
19909365
20150200015
21149606
21378271
21910624
23609447
23896411
8189062
8226994
9000133
9295024
9314552
9396765
9632805
9763615
|
SYK
|
CD36
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10358164
11907067
12524384
14568985
15536084
17101731
19909365
20150200015
21149606
21378271
21910624
23609447
23896411
8189062
8226994
9000133
9295024
9314552
9396765
9632805
9763615
|
CBLB
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
12771181
16189514
27428901
10022120
|
PTPN6
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12763134
11356834
10592173
16189514
10458769
10072516
10747947
|
CD40LG
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
CD40LG
|
BIRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
CD40LG
|
CD70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD59
|
CD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16189514
1385156
1377404
|
CD3G
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
CD3E
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
PTPN6
|
JAK3
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
18097461
15317731
16825495
19459784
16871283
|
PTPN6
|
ALK
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
18097461
15317731
16825495
19459784
16871283
|
PTPN6
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
9520455
23180781
9852037
14624462
8524272
7629131
|
PTPN6
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
11812650
8246974
9254654
9162089
|
PTPN6
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18086677
|
PTPN6
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
9520455
18988627
11021818
|
CSF3
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
JAK1
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11867689
14610620
18400509
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
JAK1
|
CSF3R
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11867689
14610620
18400509
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
JAK1
|
CSF3R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
11867689
14610620
18400509
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
SOCS1
|
JAK1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
6.0
|
1.0
|
ACSN
|
10485906
12193701
12223527
12811837
21469115
23124025
|
JAK3
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11641425
19901323
20135364
17259970
12207328
10825200
11909529
15659558
12559972
9553136
|
SOCS1
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
23331499
10950967
12223527
10485906
26192618
10707961
12193701
18988627
10201892
10856136
21469115
23663276
11133764
23124025
12811837
9202126
|
CSF2RB
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9516124
15988755
9720754
11557047
|
JAK1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9047382
16741510
11722592
10781830
|
CREB1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11413310
12388374
7513046
|
CCL5
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10734056
7622448
8642344
22633458
10733106
10699158
9289016
|
CCL5
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
10734056
7622448
14637022
22633458
9115216
9624164
10699158
11116158
12270118
7545673
9289016
9336350
10910894
8530354
|
CCL26
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
10699158
16339911
22633458
|
CCL26
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15207250
12689946
22633458
|
CCL26
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
15039444
|
GSK3B
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
102.0
|
1.0
|
Omnipath
|
20128690
16944320
11738041
20043192
12511557
11967263
16890161
22613765
14663202
23602568
8524413
24451375
19303846
12554650
8638126
22509369
18593713
16199882
21988832
23331499
19759537
10428961
9482734
22270359
19202075
17570479
16293724
15327768
10581160
17318191
11487578
22773187
26496610
16568235
17318175
19131971
15465828
26912724
25241761
24976009
21242974
22682247
10228155
23579495
12584189
23959799
15020233
10421629
10488109
11278246
9501208
18632848
10481074
10535959
10318824
9554852
17601533
9832503
21502811
9734785
23455922
|
MAX
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8425218
15121849
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
BIRC5
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9384571
11024045
9850056
16189514
11170436
|
CD14
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21737330
12752666
15814722
16115877
14739303
21737329
|
CASP8
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18073771
9545235
10872455
18329793
9727491
9463409
|
CASP8
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17170703
9535906
16713569
|
CSF2RB
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
ARNT
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
11959990
11063749
7836384
11959977
9632793
17804822
9822602
10202154
|
AR
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9822653
15350180
16492776
16344550
11161315
18819102
18031230
20610535
|
CREB1
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
10866654
18599546
15585582
7870178
8028671
11313407
16007092
8413673
11564156
15691881
9829964
15073328
20403362
11259575
17476304
17707401
20541704
16799563
7870179
11123304
27789289
7913207
12933667
8663317
8004670
11483993
12198160
9413984
|
CREBBP
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20541699
9822653
15691881
12810069
9482849
16713569
|
CSF1
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
CSF1
|
CSF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
CSF1
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
7883784
8355686
1702217
22483114
22902366
2408759
26235028
22153499
24890514
26095744
|
GSK3B
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
16944320
11348595
11967263
14663202
8524413
20080742
19797085
12040186
16611981
10671551
16039586
12615961
15465828
17928543
24063632
10671552
15020233
19575820
17444818
20537194
17052453
9832503
18455992
16371461
11274345
|
CD70
|
CD27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
8120384
21917027
26697006
7479974
9862673
8580829
12324477
8186199
9767422
15723067
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
STAT5A
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24218138
24469394
18042802
20385773
|
AKT1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
19651622
20058876
14688280
11510412
25241761
20230923
20068231
18452278
11410590
17570479
10869359
18669648
|
AKT1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
99.0
|
1.0
|
Omnipath
|
17428466
15207235
17145710
12052830
10729337
8250835
11756412
11923280
16914735
17623045
16697215
8524413
12054501
20398329
18372248
21506126
20028971
12040186
15808505
16543730
20138985
23331499
21303971
16009706
10385618
20214616
23180781
9373175
16039586
15829723
18988627
16282323
11577096
11035810
18669648
18216173
15169778
12851486
16123141
11882383
23109003
9065430
18691976
22094462
10949026
22710759
11715018
12459251
18636226
17192257
11254732
11278246
20858269
9812896
9582355
15023346
17680028
19369195
7945242
12900420
23552696
18387957
10722653
20832730
18570873
12147701
18505846
17052453
17693255
18218901
|
AKT1
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
11175347
11756412
12356771
15733869
20452955
20398329
11160957
10217147
19216069
20214616
11463845
9829964
7958915
12235136
16680151
17646672
9687510
8887554
11698596
8688081
17680028
9528766
11018520
11969286
12519783
11909979
15725726
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|
STAT5A
|
CISH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16125365
11696536
15769897
19036881
17001312
9129017
11713228
15778369
|
BIRC2
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16339151
9384571
16189514
11084335
|
HCK
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9790917
8547634
|
HCK
|
BCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
9407116
12522270
10405761
12592324
19690332
9178913
7529874
17570479
16497976
8955135
16912036
18083107
10849448
12124177
|
CREB1
|
CCNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11160720
20857405
8641461
17325033
12869629
19343785
|
CREB1
|
BDNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17599098
19712055
25031400
11719924
21335064
32603820
14735135
11377882
19046370
22179316
21677163
17456785
23946409
17164818
9581764
18063565
9581763
16337876
20100784
|
AKT3
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
20452955
9829964
20398329
17646672
10217147
|
CAMK2D
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11175347
12356771
15733869
22554507
8887554
9528766
11018520
11698596
11160957
11969286
12235136
7958915
9829964
9687510
11909979
8688081
|
GSK3B
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16568235
12162494
|
CAMK2G
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11175347
12356771
15733869
8887554
9528766
11018520
11698596
11160957
11969286
12235136
7958915
9829964
9687510
11909979
8688081
|
CAMK2B
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11175347
12356771
15733869
8887554
9528766
11018520
11698596
11160957
11969286
12235136
7958915
9829964
9687510
11909979
8688081
|
CEBPA
|
CSF3R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17082780
10233885
10453008
11830484
11753385
11978795
8695841
20864248
|
CSF3
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
10537111
10364174
15676205
16492764
|
CEBPA
|
ELANE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17360796
19620402
8756629
16247445
12949251
|
CEBPA
|
LEP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9030601
12861022
23544093
21304902
11340085
8633022
16461934
21983012
9790921
12049196
8570651
|
GSK3B
|
CEBPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
20194724
23181522
28775290
10567568
21038412
|
AKT3
|
CREB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
20452955
9829964
20398329
17646672
10217147
|
STAT5A
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11160217
12586844
14660677
15509806
22723377
|
GSK3B
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17486076
11152665
20537194
10385618
11124803
12969793
19757160
16732330
10486203
16039586
14536078
18167338
12459251
12615961
|
GSK3B
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
11152665
20537194
10385618
15252116
11124803
16331257
12969793
19757160
16732330
10486203
16039586
14536078
18167338
15326477
12459251
12615961
17092340
15212693
|
AKT3
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10869359
18451171
11293329
19493313
|
AKT3
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
12851486
15023346
21303971
11882383
17680028
9065430
23109003
20214616
22094462
23552696
20398329
21506126
20028971
12040186
18218901
|
GSK3B
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
16944320
11967263
14663202
8524413
8861947
16039586
17570479
14536078
12615961
19561641
15465828
25241761
18691976
18319725
12459251
15020233
20537194
11124803
16131838
9832503
15364936
|
CASP7
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9535906
16713569
|
BCR
|
STAT5A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
21330321
14660670
17698633
10935490
|
CD1A
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3E
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
JAK3
|
ALK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
16939498
16153455
18097461
15317731
16825495
11850821
19459784
16170336
12934099
16871283
|
JAK3
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
18250158
9382798
10037026
19088846
9047382
7777534
16189514
19414780
|
STAT5A
|
PRL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9341115
7479881
15778982
9773981
19036881
12060651
12819296
16847321
10406460
15637146
23313770
9806359
20124477
12459499
7744007
8018556
23729680
9545277
21964595
10373481
11682625
|
BIRC3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16339151
9384571
|
AMH
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14656470
|
BMP2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8006002
28977600
|
BMP4
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7811286
8702914
11282024
8006002
|
AMHR2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16446785
14746809
11420127
|
BMP2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7811286
12700180
9872992
10712517
15064755
19229295
|
BMP15
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15621726
12044914
12419820
1204491412419820
|
ARNT
|
EPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8089148
10207038
20631191
11782478
8663540
8408001
|
BMP2
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17483092
10880444
21702718
17295905
25938661
20959140
|
BMP4
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
8702914
26330344
20860622
21054789
11241215
8006002
16189514
7644468
|
BMP2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
20385559
16446785
28977600
15064755
18988627
17295905
|
BMP2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
51.0
|
1.0
|
Omnipath
|
17145710
17483092
10880444
10712517
26330344
21054789
16672363
10881198
11263668
20860622
15064755
18937504
25938661
15621726
12700180
10692589
19804412
|
ACVR2B
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
23180781
8622651
16446785
12364468
18988627
|
BMP5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11580864
16189514
|
CCL11
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
15207250
9276730
9115216
9195948
11264152
22633458
12554737
12149192
|
CCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
10488147
10699158
22633458
12218106
23597562
25450766
12149192
16102831
8642344
9169459
9005985
16339911
8676064
9276730
9207005
24702154
9712872
10733106
10706854
12761559
8609214
10854442
|
STAT5A
|
SOCS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12468433
22291912
16293640
|
STAT5A
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10674400
7744007
8732682
11092411
12683938
18388193
22698918
19819986
22166977
11564677
14532269
17412814
12970402
10373481
15677453
10803577
|
CCL15
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL8
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10699158
22633458
9115216
|
CCL23
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9886417
9558365
12381680
10699158
10660125
22633458
|
CCL3L1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11170631
11449371
12381680
9115216
9624164
7545673
10202040
10660125
22633458
8530354
|
CCL14
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9687537
9548457
15905581
12381680
20483925
9346309
9405404
24218476
22633458
11085751
|
CCL8
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10699158
9005985
|
CCL28
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
22633458
12964882
|
CCL3L1
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11449371
7594543
22633458
|
CCL15
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL13
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9276730
10733106
9005985
10699158
16339911
22633458
12149192
|
CCL14
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9548457
9346309
11085751
|
CCL24
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
22633458
10733106
10699158
16339911
12218106
|
CCL18
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
10640766
29637711
23999500
24218476
22633458
23951310
|
CD3G
|
CD1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3G
|
CD1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD1A
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CCL20
|
CCR6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10498628
9223454
10488147
9169459
9294137
10699158
12081481
24218476
22633458
12964882
|
CD3G
|
CD1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
AMH
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8889695
23331499
8119126
16446785
18988627
79972308889695
7997230
|
CCL8
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9115216
10699158
9195948
22633458
12554737
12149192
|
CCL24
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15207250
|
CCL13
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9276730
10699158
24890717
9195948
22633458
12554737
12149192
|
CCL27
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10781587
11821900
12718728
10725697
22633458
|
CCL28
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
10781587
22633458
|
CCL25
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
CAMK2G
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
9768837
8798667
|
CCL25
|
CCR9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10498628
10699158
11159507
22633458
10229797
|