Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYH9 CCDC180 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
MLH1 PMS2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MLH3 MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 10615123 11292842 27229929 24443562 32814343
PMS2 MSH2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748159 12799449 17148452
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 19704002 21075308 7542762 7797556 19372587 29720121 11940572 17875712
YBX1 SMAD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12917425 12446674 16278212
MSH2 PMS2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
MSH2 MLH1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 12799449 30770470 10748159 25241761 31843968 10783165
MLH1 MSH2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PMS2 MLH1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 20706999 33961781 25502805 30770470 10748159 22939629 26496610 16338176 18768816 17148452 11793469 14676842 11429708 10037723 15225546 12799449 12584560 17581638 25077178 20533529 16083711 11292842 20978114 22252508 18206974 12810663 19015241
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
MLH1 MLH3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15703371 16612326 16697054 18157157 18406444 19847258 20478261
MLH1 PMS2 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10882712 11900249 12556884 12648680 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17036055 17303408 17581638 17884153 18157157 18406444 18543256 18931676 19151707 19473888 19595721 19596235 19596236 19622404 19686080 19805513 19809470 19847258 20173781 20478261 21376743 22101340 22257761 22373527 22743550 22824526 23085398 24050180
MLH1 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 25077178 17145710 10748159 17148452 11429708 18206974 19015241 16338176 20706999 15225546 25502805 19022408 12584560 26496610 14676842 16083711 11793469 10037723 11292842 22252508 17581638 12799449 18768816 20533529 31515488 20978114 12810663
STK11 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 25763354 17875968 15987703 16107342 11035045 12077256 18321849 23379765 21779440 12297295 25336918
SRC PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24830552 22891331 12869565 21532586
PTPN12 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19595712 18482983
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368