Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
CHRM5 ASPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ASPH F10 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
SP1 COL1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19558215
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
SQSTM1 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12371907 11796223
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
RYBP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP1LC3A SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
VAV1 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
VAV1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PDPK1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
VTI1B STX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
ECSIT NDUFAF1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
LYZL2 ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH STXB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH SEC20 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH CIA30 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BMI1 EFTU â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
EFTU ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 32296183
ASPH CV032 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NTAQ1 ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CHLE ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
C1QR1 ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
C1QR1 ECSIT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH TM160 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH TM192 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH F162A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH STEA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH C109B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 ACAD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ASPH ACAD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VTI1B ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
NELL2 ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH ECSIT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH STX8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH LEMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH MCU â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH STX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASPH EXD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
PAK1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12374744 16452229
SOX2 PAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HLAE ASPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PTC1 ASPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NOE1 ASPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FBLN7 ASPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PVRL3 ASPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX4 STX8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 32296183
STX4 RAB5A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11884531 16189514
HTT SQSTM1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CV032 MCU â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 27173435 32494073
HIF1A JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
STX4 STXBP3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
SQSTM1 PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 20808283 8075909
CIA30 ECSIT â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24344204 20816094 17344420 26186194 28514442
ACAD9 CIA30 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24344204 20816094 28514442 32877691
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 SP3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
ASPH LRC59 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 31536960 34079125
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
ESR1 SP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10816575 31527615 16651265
SP1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25879517 16478997 17215518 16713569 33572115 10506225
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EP300 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12573436 10999956
SP3 ASPH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17681019
SP1 ASPH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17681019
COPS5 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11707426 18926707
SP1 F10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8567696
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
PRKCZ MAPK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20538799 11158308
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
EP300 MEF2A â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PRKCI SQSTM1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PRKCZ SQSTM1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
MAP1LC3A SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
STX8 VTI1B â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SQSTM1 MAP1LC3A â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 19427866 7034152
STXB3 STX4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 12832401 12773094 34079125 29360461 28514442 10194441
MCU SMDT1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HIF1A ARNT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 12391259 10085255 16954218 7836384 17916562 26496610 8663540 34592152 14764593 20603618 14668441 21512126 11606485 26350169 9079689 24056783 19845609 27684187 11782478 19168635 23363003 26160453 28628118 15850782 17197389 21620138 15833858 23086815 24434214 20458141 18024476 23458834 12810720 28514442 15347669 9704006 27320910 20562859 11829741 15031145 21435239 20049704 15479785 20932347 12393189 11025203 16861921 9159130 10671489 16520375 15615775 17213817 28205554 23796364 15319539 11593383 19251694 20699359
HIF1A EP300 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 18268343 15154850 12914934 19074848 25192544 22789427 20829524 21148070 17502379 26826385 22075993 16543236 19680224 20603618 19589782 11063749 23618863 26135796 27808477 22219185 15155277 11823643 17906695 19666581 21187066 16189267 8917528 23746844 19940151 19071119 26944191 15261140 24421387 20000859 12778114 14691445 12042299 22684029 12588875 17382325 23966271 15342390 22735262 27320910 26751287 24821806 23448368 11959990 15280364 11940656 19696166 20620956 16081065 22908229 18047470 16847340 22807441 23880760
ACAD9 NDUFAF1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ACAD9 ECSIT â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STX4 STXBP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NDUFAF1 ACAD9 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ECSIT ACAD9 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
NDUFAF1 ACAD9 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ECSIT ACAD9 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
ESR1 CAV2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12711000 12138116 18414489
SP1 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10091149 16575855 9666093 10775443 12138160 11348466 17698844 16564026 10082137 7504695 7590335
SP3 COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9666093 10082137 17698844
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
SQSTM1 CUL3 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
ECSIT NDUFAF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ECSIT NDUFAF1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
PAK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18521086 26944939 16778166 18755239 21893191 15178330 19205871 29548483 26554417 27003261 24505617 16452229 15193262 19557173 15642175 12374744 19465939 17604944 25447917 20179234
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
HIF1A FAM162A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 15082785
MEF2A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12574153 10330170 20590529 9252389 8355696 12016267 19389706 7760790 1406636 10403485 12054430
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
MAP1LC3A SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 20061800 23022382 23459205 35044719 22963397 36036324 31053714 21045561 25921531 19250911 17580304 21628531 20204693 28740232 23640897 25686248 24100292 26075355 20562859 22658522 25984893 21460636 16286508 19427866 32296183 23989536 19021777 26268733 22714671 24998849 18653543 31366950 33436498 16169070 23239879 26754771
MAPK7 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 9858528 10330143 9753748 16189514 27713878 18988627 17785444 10849446 12586839
PDPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11134074 21726627 21209852 10995762 23885116 26009991 26238471 10551809 25335797
PDPK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12887331 14500673 11222751 18691976 10075713 20332120 9768361 9748166 17335005 10357815 16189514 11141077 16051884 11781095 10764742 14604996
PDPK1 PRKCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10764742 16189514 27554858
PRKCZ SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23148884 16943418 18258854 19464346 27320013 17049555 20953893
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9762895 12736330 17012241