Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
THRA THRSP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2158623 21529443
ERBB2 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 8026468
KRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
THRA THRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1782215 17761769
IGF1R ERBB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17307140 30898150
AKT1 STK11 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 24412244 28205554
AKT1 AURKA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 24412244 28205554
ERBB2 FGFR4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30898150 28628118 28205554
PTPN1 IGF1R â—¼   DEPHOSPHORYLATION ✅ - 0.87 0.87 Signor 11884589
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
THRSP ZMYND12 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
THRSP MID1IP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20233797 18556348 24277613
AKT1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 23397142
SMAD4 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22775504 17452626 24625091
WT1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23298185 23945386 10753894
IGF1R PTPN1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
USF2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14757763 15184388 15983197 16488890
WT1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8390684 7497000 16698800 15345673 11001824 9076342 12444079 10499530 11896622 7791758
PTPN1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 11884589 15976035 8702689 16926280 8999839
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
AKT1 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17081983 18691976 11579209 16189514 10480872
FGFR4 PIK3CA â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17505008 18757403 21666749 11689702 21711248 11739186 21160078 14534538 15448205
KRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196