Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAD50 MRE11 â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
TERF1 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
TERF2 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
XRCC6 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
BRCA1 H4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16628214 30804502
BRCA1 POTE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34112789 29656893
NBN TE2IP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 34079125
ZBT10 TE2IP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30629181 34079125
RIF1 TE2IP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12753906 34079125
ARL4D TE2IP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TE2IP MDC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15383534 34079125
TE2IP XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15383534 15100233
ARL4C TE2IP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMRC2 MDC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29656893 26344197
MRE11 NBN â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
ARL4C TERF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARL4D TERF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BRCA1 TINF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34112789 29656893
PR40A TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TAD2B TE2IP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CC106 TE2IP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FBRL TE2IP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DCR1B TE2IP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 24981860
BRCA1 TE2IP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34112789 29656893 34079125
FBRL RECQ4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 29229926 26186194
FBRL TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DCR1B TERF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26496610 16730175
CC106 TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TAD2B TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BRCA1 TERF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 29656893 34112789
BRCA1 TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 25184681 29656893 34112789
TERF1 TE2IP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 15316005 26496610 16880378 26186194
BRCA1 SMRC2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10943845 26831064
TE2IP POTE1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15383534 33961781 15316005 26496610 16880378 28514442
ACD TE2IP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15383534 33961781 15316005 26496610 16880378 28514442
TE2IP H4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 30804502 21044950
TE2IP PPM1G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21044950 34079125
TE2IP RECQ4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29229926 21044950
ACD TERF2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15383534 16880378 15231715
PR40A TE2IP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
POTE1 TERF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15383534 33961781 26496610 19651898 16880378 19287395 20811636 28514442
TE2IP DPOD1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 34079125
TE2IP NUMA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 34079125
TE2IP MRE11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15383534 22939629 15100233
TE2IP SMRC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 34079125
TE2IP CI078 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 34079125
TE2IP PRP16 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 34079125
TE2IP GPKOW â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 34079125
PPM1G XRCC6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28330616 30585729
RAD50 TERF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ACD TERF1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TERF2 XRCC6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
TE2IP UCHL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29126443 21044950
TE2IP PP1RA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26496610 19287395 34079125
TERF2 MRE11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18212065 22939629 10888888 19287395
MRE11 XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 10508516 26344197
MDC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 17525332 15569676 29656893 12607005 19766185 12611903
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10426999 29656893 10783165 11504724 25659039 25939603 25184681 19244116 18171670 12124328
TERF2 NBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22939629 10888888 19287395
XRCC6 TERF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10984620 26496610 21044950
MDC1 RAD50 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
ACD POTE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 33961781 21044950 17237767 26365187 15231715 17632522 26496610 17237768 16880378 16713569 28514442 15181449 16189514
POTE1 TINF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 33961781 21044950 15316005 15231715 26496610 16880378 12768206 20811636 28514442 15181449
TE2IP RAD50 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 22939629 15100233
TE2IP TERF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 22939629 26496610 28082411 21044950 26450775 26344197 10850490 21829167 16880378 19287395 23307557 27214791 15316005 23086976 15100233 15383534 29126443 21217703 19164295 10888888 19651898 14565979 34079125
TINF2 TE2IP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 33961781 15316005 26496610 16880378 19287395 28514442 15181449
SLX4 TE2IP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22902628 31495888 19596235
TE2IP XRCC6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 21044950 26496610 15100233 34079125
MDC1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12607003 30179224 29656893 20081839 12607005 14519663 18583988
BRCA1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10426999 11353843 17349954 23530059 24413181 16391231 29656893 11504724 25184681 10783165
NBN MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12750284 12419185 24413181 21884979 24981860 22939629 12679336 10426999 28369484 17526493 9705271 26455393 12607003 17612497 12447395 22464731 22078559 22231403 34348893 28363998 11062235 15758953 11238951 23530059 33558481 15734743 34038735 30179224 12861053 18458108 19270065 17500065 10783165 30440001 22941933 19244116
DCR1B TERF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16606622 33961781 24981860 26496610 21217703 20479256 16730175
TINF2 ACD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 28514442 33961781 21044950 32296183 25910212 15231715 26496610 16880378 16713569 25416956 15181449 16189514
TERF2 RAD50 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18212065 22939629 10888888 19287395 15100233
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
ACD TINF2 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
TERF1 TINF2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
POTE1 TERF1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 26496610 26186194 12768206 20811636 28514442
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
RAD50 NBN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 19197236 22939629 12679336 10426999 26344197 17526493 9705271 12607003 17612497 12447395 22464731 34348893 11062235 15758953 12124328 11238951 26215093 23530059 15734743 16391231 24651726 30179224 17500065 30440001 22941933 10783165
TINF2 TERF1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10581025 15383534 28514442 21044950 19487455 33961781 15316005 11701125 26496610 16880378 16169070 15133513 26186194 20811636 17589526 25416956 15181449 28216227
NBN TERF2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SLX4 TERF2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
TERF2 TINF2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAD50 MRE11 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12750284 24413181 24981860 19197236 22939629 31501894 30733337 10508516 26344197 8756642 28369484 9705271 26455393 12607003 16163361 11504724 34348893 28363998 11062235 26215093 27173435 23530059 33558481 15734743 16391231 24651726 17694070 34038735 17500065 19270065 30179224 10888888 10783165
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MRE11 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RAD50 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19197236 16163361 10888888 8756642 17713585
MRE11 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22464731 26455393 12861053 17500065 15734743 12419185 19270065 22078559 19244116 21884979 12679336 11238951 12607003 9705271 17713585 10783165 12447395 10426999 18458108 15758953
ACD TINF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 16880378 15181449 25416956 21044950 15383534 31515488 26496610 16713569 15231715
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
RAD50 MDC1 â—¼   PHYSICAL_INTERACTION 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
XRCC5 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MDC1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RAD50 MDC1 â—¼   SHARES_COMPLEX 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
NBN RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RIF1 RAD50 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TINF2 TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TINF2 TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
MDC1 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368