Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PDGFRB STAT3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 17145802 17496910
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
PDGFRB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 9484840
STC2 CARHSP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STC2 EIF2B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STC2 AIFM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STC2 PPP1R8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STC2 PEBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESR1 STC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17486082 18414489
STC2 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STC2 POLR3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ANXA2 STC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STC2 POLR2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTN STC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STC2 ARHGEF40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STC2 ADAM11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CRP STC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BRD4 MED1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19766566 33567268 31239290 20098423 30554943 32416067
CCNJL STC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 IGF1R â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10749889 24051437 14764897 28555617 16113100
HIF1A STAT3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
STAT3 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15735682 18985005 23604114 23991099
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ESR1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 MED1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AHR ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15837795 19460354 12612060 27420286 17392787 10620335 9611253
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
RELA STC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
MED1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18391015 15886699 31527615 10760302 12738788 9653119 10770935 12837248 11867769
BRD4 RELA â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
STAT3 HIF1A â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10347215 10973499 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 18985005 19380816 20093776 20237412 20406969 20581311 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19265129 18644974 16007214 20924113 17597020 23991099
STAT3 CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9566874 12667216 18684932 8621622 20978825 16116232 10880233 18292576 23361365
STAT3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15735682 18985005 10973499
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
RELA HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18498249 17898080 23185316
HIF1A STC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 23746844 18394600
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335