Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-1 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 SMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-1 SMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
NSMCE2 TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19308705
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
TK1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PJA1 SMC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EID3 NDNL2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
STN1 NSE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STN1 SMC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STN1 SMC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STN1 MAGG1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN597 MAGG1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN597 NSE4A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN597 NSE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NSE1 F178A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN597 NSE2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN597 SMC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN597 SMC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BRCA1 TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 25184681 29656893 34112789
PJA1 SMC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 30185588
NDNL2 SMC5 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
SMC5 F178A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32389690 33961781
SMC5 SMC6 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MAGG1 NSE2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 18086888 26344197
MAGG1 SMC5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 29225034 18086888 26344197
MDC1 SMC6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
PJA1 NSE4A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 28514442 30185588
NSE4A SMC6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 18086888 26496610 26186194 28514442
EID3 NSE2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32389690 26186194
NSE2 SMC5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32389690 16055714 22751501 26344197
NDNL2 NSMCE2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NSMCE1 ZNF597 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMC6 F178A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32389690 26496610 33961781
EID3 NSMCE2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MAGG1 PJA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 30185588 20864041
MAGG1 SMC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 18086888 26344197 29225034 26496610 27427983
MAGG1 NSE4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 18086888 21364888 27427983 30185588 20864041 26186194 28514442
NSE4A NSE1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 18086888 30185588 26186194 28514442
NSE4A SMC5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194 30185588
NSE1 NSE2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 18086888 26344197 32389690 26186194 28514442
SMC6 NSE2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 18086888 26344197 26496610 22751501
MDC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 17525332 15569676 29656893 12607005 19766185 12611903
NDNL2 SMC6 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
EID3 MAGG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21364888 32389690 26186194 28514442
MAGG1 NSE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18086888 26344197 21364888 29225034 27427983 20864041 32389690 26910052 26186194 28514442
EID3 NSE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18086888 21364888 32389690 26186194 28514442
NR1I2 SMC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
NR1I2 NSMCE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
NSMCE2 SMC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055714 18086888
SMC5 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 SMC5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NDNL2 NSMCE4A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
NSMCE1 NSMCE2 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
EID3 SMC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EID3 SMC6 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
NSE1 SMC6 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 18086888 26344197 14701739 26496610 32389690 26186194 28514442
NSE1 SMC5 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 18086888 26344197 16055714 26186194 28514442
EID3 NSMCE1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NSMCE1 NSMCE4A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NSMCE4A SMC5 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NSMCE4A SMC6 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NSMCE1 SMC5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NSMCE1 SMC6 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NDNL2 NSMCE1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NSMCE2 SMC6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NSMCE2 SMC5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SMC5 SMC6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NSMCE3 NSMCE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 21364888 32389690 20864041 27427983 18086888 26910052
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
SMC6 SMC5 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 15496928 15549137 15655342 16697054 18001825 18171670 18212739 19217833 19270065 19490890 19772495 19847258 20021983 20064462
MDC1 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368