Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
PJA1 SMC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STN1 SMC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STN1 SMC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PJA1 SMC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 30185588
SMC5 SMC6 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MDC1 SMC6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NSMCE1 ZNF597 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EID3 NSMCE2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MDC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 17525332 15569676 29656893 12607005 19766185 12611903
NSMCE2 SMC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055714 18086888
NSMCE1 NSMCE2 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
EID3 SMC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EID3 SMC6 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
EID3 NSMCE1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NSMCE1 NSMCE4A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NSMCE4A SMC5 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NSMCE4A SMC6 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NSMCE1 SMC5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NSMCE1 SMC6 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NSMCE2 SMC6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NSMCE2 SMC5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SMC5 SMC6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NSMCE3 NSMCE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 21364888 32389690 20864041 27427983 18086888 26910052
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
SMC6 SMC5 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 15496928 15549137 15655342 16697054 18001825 18171670 18212739 19217833 19270065 19490890 19772495 19847258 20021983 20064462
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368