Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AXIN1 SMAD7 â—¼   COLOCALIZATION 2.0 0.8 intact 16601693 5218493
SUMO2 RN111 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 23530056 23086935 23751493 21252943 21693764
RN111 PML â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22493164 23530056
RN111 UBXN7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AXIN1 RN111 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26871637 16601693
RN111 SMAD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23530056 17591695 18451154
PML SMAD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 15356634
RN111 SMAD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23530056 14657019 18451154 17591695 18950738 16189514
CSK21 RN111 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25416956 21516116 29892012 32707033
SMAD7 AXIN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18593713 16601693
PML CSK21 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20625391 19217413 22406621 16873060
CSK22 RN111 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 26186194 33961781
SUMO2 PML â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25027693 21148299 23543742 17000644 20797634 22155184 21779164 19553342 9452416 17081986 16713569 24637324 21693764 19471022 21252943 15940266 16189514 22578841 20826694 24190887 28851805
RN111 SKIL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17510063 23530056 17591695
SMAD2 SKIL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15231748 10531062 11691834 16959829 12764135 12426322 18729074 22442258 25059663
SMAD3 SKIL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15231748 10531062 17469184 11691834 16959829 11306568 12764135 12426322 22442258
SKIL SMAD3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
SKIL SMAD2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CSK22 CSK21 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19011756 23455922 24981860 26344197 25519132 25852190 26496610 30279146 26186194 27705803 28514442 32707033
AXIN1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16601693
PML SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15356634
SKIL SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23154975 16442497
RN111 SMAD7 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 23530056 27292644 14657019
AXIN1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11438668 23331499 18988627
PML SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 15356634 16189514 18988627
SKIL SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 12764135 15221015 23331499 18729074 22442258 25059663 16959829 18334480 10531062 17510063 15496141 12793438 15231748 11691834 12426322
SKIL SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12764135 23331499 21071413 22442258 11306568 16959829 10531062 12793438 17469184 15231748 11691834 12426322
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110