Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMO ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15618519 23074268
ARRB1 SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15618519
GLI3 PTCH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14691458
PTCH2 SMO â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
GLI1 SHH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19384336 16855373 9247260
DHH PTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 98118519811851 11331587 9811851
KIT DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11071635 11825908
SMO GLI1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 17641202 18820483 19081070 20215540 23031257
GLI3 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12435627 14723851 10075717 16571352 19667090
GLI2 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16571352 15175043 12165851 9636069
GLI2 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18813803 16880536 19190345 18698484 15087129 17845852 19049965 11001584 20107231 20712011 15520176 16406505 17000779 16413481 16571352 16396903 9609833 18497536 14555646 9216996 20581804 11493558 15140221 16054035 20143239
GLI1 PTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16158046 18813803 19219074 16880536 21059263 11960000 19190345 15087129 21442356 16328026 19736394 11001584 12138125 20107231 15520176 16406505 17000779 16571352 16396903 14555646 17035233 16054035
SMO GLI2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 17641202 18820483 19081070 20215540 23031257
GLI3 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
SMO GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253
GLI2 PTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18813803 16880536 19190345 18698484 15087129 17845852 19049965 11001584 20107231 20712011 15520176 16406505 17000779 16413481 16571352 16396903 9609833 18497536 14555646 9216996 11493558 15140221 16054035 20143239
SMO GLI3 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 17641202 18820483 19081070 20215540 23031257
SMO GLI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253
GLI3 PTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
IHH PTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 29274272 9811851
SHH PTCH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 9811851
PTCH2 SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9811851 23331499 18988627
SHH SMO â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18754008 20495383 22354771 24856585
SHH SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16867986 8906787