Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCOA3 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
PRGR SRC â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15601848 12612073 15937332 12650714
ESR1 UBE3A â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 9891052 16772533 29388081 16314411 31329371 22865929
PRGR CDK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15601848 21447625
CDK2 HS90A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 21319273
PRGR PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10750018 33846359
NCOA1 NCOA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17476305 18267973
HS90A STAT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12559950 16189514
HS90A PRGR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18620420 33846359 9178755
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
STAT3 PRGR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20876300 21184768
PRGR SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18202149 21184768
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 17627277 5222291
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
SP1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17471507 24396070 21184768 16931573
PRGR XRCC5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10750018 33846359
PRGR XRCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10750018 33846359
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
ESR1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
PRGR NCOA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21273440 16728408 19706513 10722692 7481822 29202468 16352595 12529333 10757795
NCOR2 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9702189 14715875 20392877 12738788 9171229 23403292
ESR1 FKBP5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27483141 9222609
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
PRGR FKBP5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22891251 12538866 20661446 33846359
PRGR UBE3A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9891052 16713569
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
NCOA1 STAT3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17471507 11773079 16713569
HS90A SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 1310678 16844778 22315411 28537252 32707033
HS90A ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27483141 20353944 12962497 23912458 11911945 21503962 18388150 22939624 23403292 19805454 9222609 15538384 17699868 9115298 16037132
PRGR NCOA3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10757795 15937332 16728408 19357364
PRGR JDP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17347654 12101239 12650714
CDK2 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10660621 21550420 17570479
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
FKBP5 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 20661446 25036637 9001212 12538866 22863883 10642522 21235734 21170051 21360678 29079741 23999428 28363942 19875381
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
SRC STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 21573184 15313931 11294897 8657134 18070987 10918587 12244095 19372587 12626508 8626374 14551213 16713569 8272872 11350938 9566874 12576423 11940572 15735682
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
NCOA1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 17400812 17495236
NCOA1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20608937 15604093 12738788 11003650 11250900 18451880 11867769 15140878 16282588 11165056 11376110 17627277 14715875 10731636 9259327 17363140 11113179 16606617 12630920 9121466 10760302 26487511 23975195 11682626 12714702 9192902 9192892 23874500 11358671 16713569 11014206 10454579 9773983 12554772 9427757 10598586 10409727 9774463 12574227 16957778
PRGR ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26153859 12612073 22396492
NCOA3 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26153859 20392877 15383283 14766010 25728767 21182203 15145444 18484708 11376110 14966289 9346901 20181721 26166704 16331275 28844863 11389589 11050174 12630920 19491275 17158759 23403292 12714702 17646391 9192892 11353774 16923966 18645020 16713569 30418174 10490106 9765300 12554772 26487511
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
NCOR2 PRGR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10757795 17347654 12771131
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
NCOA1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11773079 16713569 15313931
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877