Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
NCOA3 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PRGR SRC â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12650714 15937332 12612073 15601848
PRGR PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33846359 10750018
PRGR CDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21447625 15601848
CDK2 HS90A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 21319273
NCOA1 NCOA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17476305 18267973
HS90A PRGR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9178755 18620420 33846359
HS90A STAT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12559950 16189514
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PRGR SP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21184768 18202149
STAT3 PRGR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20876300 21184768
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
PRGR XRCC5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33846359 10750018
PRGR XRCC6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33846359 10750018
PRGR NCOA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16728408 29202468 16352595 21273440 10722692 12529333 10757795 19706513 7481822
NCOR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9171229 20392877 12738788 14715875 23403292 9702189
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
ESR1 FKBP5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27483141 9222609
PRGR FKBP5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33846359 12538866 22891251 20661446
PRGR UBE3A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9891052 16713569
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PRGR NCOA3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15937332 10757795 19357364 16728408
PRGR JDP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12650714 12101239 17347654
HS90A ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18388150 23912458 17699868 9222609 15538384 21503962 22939624 20353944 16037132 19805454 27483141 23403292 11911945 12962497 9115298
HS90A SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16844778 22315411 31980649 28537252 1310678 32707033 16189514
NCOA1 STAT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11773079 17471507 16713569
NCOR2 PRGR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12771131 10757795 17347654
PRGR ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12612073 26153859 22396492
FKBP5 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 20048054 10642522 12538866 28363942 9001212 21170051 20661446 21235734 19875381 22863883 23999428 21360678 29079741
CDK2 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10660621 21550420 17570479
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
NCOA3 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18484708 20181721 19491275 10490106 25728767 26166704 12554772 18645020 16923966 16331275 16713569 11376110 21182203 23403292 11050174 9192892 26487511 28844863 11353774 15145444 17158759 11389589 14966289 9346901 26153859 17646391 20392877 15383283 12630920 9765300 12714702 14766010 30418174
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
SRC ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043237 17284441 17400812 15604093 11032808 17921256 18451880 15020686 12736255 11564893 23065768 10454579 20935677 17363140 16957778 14963108 11013076 29720121 15784253 24498420 17627277 12630920 22328528 14766010 24051437 7539106 27420286 15140878
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
NCOA1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 17400812 17495236
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
NCOA1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11773079 16713569 15313931
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
SRC STAT3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 16472776 17192274 19930715 22131018 22677902 23589069 23691193 24030100 24403062 25687758 27036022 27452906 29556339
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368