Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ANK3 SCN5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19805355 0907138106
ICAM1 CDH5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18783313 26556953
CDH15 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21255999 9545347
ITGB2 JAM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17379836 17525755
ITGB2 ITGAL â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19161977 21270398
ITGB2 ITGAL â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19161977 21270398
SPN GLG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
SPN SELPLG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
SPN SELE â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
ITGAV PECAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8838667 7542249
ITGB1 JAM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12070135 17525755
ITGB1 JAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12070135 17525755
ITGA4 JAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12070135 17525755
ITGA4 ITGB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12626562 19454690
ITGA4 JAM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12070135 17525755
ITGA4 ITGB7 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12626562 19454690
CDH1 ITGB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15330449 16002701
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
GATA3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20189993
PVR CDH1 â—¼   COLOCALIZATION 2.0 0.8 intact 5224413 17717529
HLA-C CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12899833 10809759
ICOSLG ICOS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 11007762 20116985
CD226 NECTIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15607800 16904340
NECTIN1 NECTIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215384 12011057
CD4 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQB1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11535811
HLA-DPA1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12899833 16189514
PTPRC CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12370829 6671521
HLA-B CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9331948 10809759
NLGN4X DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11368788 18923512
NLGN3 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9278515 18923512
NLGN2 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9278515 18923512
HLA-DRA HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
NRCAM ANK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7961622
CTNNB1 NRCAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12183361 17724465
FRMD5 CTNNB1 â—¼   COLOCALIZATION 2.0 0.8 intact 22846708 8385346
PTPRM CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15588985 7642713
OCLN SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NRCAM ANK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11449000 7961622
CNTNAP1 CNTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11069942 9118959
SDC2 SDC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC3 SDC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC4 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC4 SDC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
NTNG2 LRRC4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8300478 21946559
LEF1 NRCAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12183361
HLA-DQB1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11376336 5214072
HLA-DQA2 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQB1 HLA-DQA1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HLA-DQA2 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
PTPRD LRRC4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20139422 19252495
EPHB2 NRCAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24023801
PTPRF LRRC4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20139422 19252495
SDC2 SDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC3 SDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC1 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
GATA3 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19674970 11397697
SDC2 SDC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC3 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
EPHB1 NRCAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24023801
SELE SELPLG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
SELE GLG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
NLGN4X NRXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20543817 18923512
NRXN3 NLGN2 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 22626547
NFASC NRCAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32822567 11724816
SELPLG GLG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
PTPRS LRRC4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20139422 19252495
CLDN16 CLDN19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22373575 8387781
NRXN2 NLGN2 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 22626544
NLGN3 NRXN2 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 18923512
JAM3 JAM2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11823489 21982860
ACTB ICAM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 23463506
CD22 PTPRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10648410 10228003
NLGN3 NLGN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 MACF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
FRMD5 NRCAM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 33961781
NLGN3 NLGN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ITGA4 MADCAM1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HLA-DQA2 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
KCNQ3 KCNQ2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12890507 12524525
ICAM1 ITGB2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HLA-DRB1 HLA-DRA â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220278 7477400
ITGA4 ITGB1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ITGAV ITGB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CD86 CD28 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27708164 21931534 11021528 7513726
SPTA1 ANK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15929114 2971657
CD8A CD8B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CDH5 CTNNB1 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 5219258 17057644
CNTN1 PTPRB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9584610 9049255 7628014 12700241
ITGAL ITGB2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SELP SELPLG â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ALCAM CD6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TIGIT PVR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27978489 21982860 28515320
PTPRD PTPRS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9566880 22357843 28675297
CD226 PVR â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
LRRC4C NTNG1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CD274 CD80 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CD86 CTLA4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11021528 25241761 7694153 12606712 21982860 7513726 11162656 12582153 11279501 12071705
CTLA4 CD80 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11279502 20587542 21982860 7545666
ANK1 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
L1CAM ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ACTB ANK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ANK1 ACTG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
L1CAM ACTG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ACTG1 ANK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
GATA3 CD40LG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18719603
CD2 CD58 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 19398758 19494291 26794910
CD2 CD58 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 19398758 19494291 26794910
CD2 CD4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
CD28 CD80 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 2164219 7964482 21982860 1847722 7545666
LEF1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22933707 17452626 8892228
CD226 PVR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30591568 21982860 12913096
CD58 CD4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19398758 19494291 26794910
CADM3 CADM1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12050160 16467305 17967169
HLA-DRA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
SPTA1 ANK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ANK1 SPTAN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
NFASC ANK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9804856 7961622
CTNNB1 VCAN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12095419 15668231 15579438
SPTA1 ANK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
SPTA1 L1CAM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
L1CAM SPTAN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
GATA3 CD8A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11937547 8413295
ICAM2 ITGAL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15023143
HLA-DQA2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
NCAM1 L1CAM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8509458 10611478 2295682
EPHB2 SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16198615 11580899
LRRC4B PTPRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23345436 32589946 19252495
GATA3 NRCAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19735555
GATA3 CD8B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11937547
SELL SELPLG â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7521878 17322099 14615387
SELPLG ESAM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7521878 17322099 14615387
CDH5 CTNNB1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HLA-DMA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
HLA-DPA1 HLA-DPB1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ITGA6 ITGB1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CDH2 CTNNB1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CTNNB1 CDH2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 36950384
DLG1 DLG3 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 33961781 12351654 26496610
PTPRD SLITRK1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CD40 CD40LG â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
PVR TIGIT â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ICAM3 ITGAL â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
HLA-DMA HLA-DRA â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PDCD1 PDCD1LG2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
DLG4 DLG3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10026200 28973854
CD80 CTLA4 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
CD86 CTLA4 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
NLGN1 DLG4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9278515 11937501 30864948
HLA-DRA HLA-DRB5 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HLA-DMB HLA-DRA â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
ICAM1 ITGAL â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CD274 PDCD1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CTNNB1 LEF1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HLA-DMA HLA-DMB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDH3 CTNNB1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
HLA-DRA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HLA-DQA1 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CD80 CTLA4 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11964292 12810107 14764699 15197224 17513775 17629517 18585785 20231889 22437870 23390297 25215878 25582338 26405600 7512027 7523569 9359474
CD86 CTLA4 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10477595 11207245 11964292 14764699 15034038 15197224 17513775 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 7523569 8920882 9359474
CTLA4 CD28 â—¼   DOWN_REGULATES ✅ - 12.0 1.0 ACSN 10921877 11093160 12370081 16227604 16885030 16916641 18292600 19890961 21159657 21376459 22116087 22437870
CD80 CTLA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 21530327 21422170 17953528 22437870 11279501 23954143 11279502 20587542 31757674 7545666 10583602 21982860
CD86 CTLA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 17145710 23223433 11162656 9856951 11976720 12582153 11279501 12071705 7694153 7513726 21530327 25241761 22437870 10583602 21982860 23954143 12606712 11021528
CD226 ICAM1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10591186 12913096 14676297 19029380 22285893 24337740 24658051 26552706 26840537 28893624 8673704
ICAM1 ITGAL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11786177 16595626 16354667 12526797 23602662 11279101 16189514 14507735
ICAM1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 4062888 12208882 11279101 16189514 10352278 20187292 14507735 7642561
ITGB2 F11R â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 15681301 15528364 17525755 11812992
VCAM1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10438935
ICAM3 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15728350 11353828 7822326
ICAM2 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15023143 16189514 9786897
ITGAV L1CAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11553709 19161977 8636223 9003039
ITGB1 ITGA4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
ITGB1 ITGA4 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
VCAM1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12097820 22623428 19738201 19057841 11751331
CD40LG CD40 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD40 â—¼   PROTEIN_INTERACTION 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
ICOS CD40LG â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10426994 11907067 15536084 16713974 20116985 21708958
CD40LG CD86 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD80 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1280226 1374165 19426221 7516405 11163401 7543281 12324477 10647992 17183360
CD58 CD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30368623 23602662 16189514 7544396 21982860 11575926 7525848 1377404
MADCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10702270 9873398 8600538
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
MADCAM1 ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8600538 9233649 7687523 12100519 15958805
CDH1 ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7969453 10837471
CD80 CD86 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10477595 11207245 11964292 12810107 14764699 15034038 15197224 17513775 17629517 18585785 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 25582338 26405600 7512027 7523569 8920882 9359474
CD80 CD86 â—¼   PROTEIN_INTERACTION 25.0 1.0 ACSN 10477595 11207245 11964292 12810107 14764699 15034038 15197224 17513775 17629517 18585785 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 25582338 26405600 7512027 7523569 8920882 9359474
CD40 CD80 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD80 CD28 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11964292 12810107 14764699 15197224 17513775 17629517 18585785 20231889 22437870 23390297 25215878 25582338 26405600 7512027 7523569 9359474
CD80 CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21530327 7964482 22437870 2164219 1847722 23954143 15610849 7545666 21982860 21487479
CD80 CD274 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23417675 24819296 18585785 17629517 20587542 31000591 31757674 21982860 18173375
CDH1 CDH4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDH1 CDH2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 CDH2 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 CDH4 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CDH2 CDH4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH2 CDH4 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18948590 20398329 21506126 20028971 12040186 12604612 21303971 20214616 17098867 11882383 22094462 8120095 21357690 17679699 17680028 12151522 17057644 21255999 18218901
HLA-G CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1908512 10843658 10809759
CD40 CD86 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD86 CD28 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10477595 11207245 11964292 14764699 15034038 15197224 17513775 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 7523569 8920882 9359474
CD86 CD28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21530327 22437870 18205792 23954143 11021528 21931534 21487479 7513726
ICOSLG ICOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 21955433 16951355 23954143 29879883 11023515 14599850 25769613 10657606 11956294
NECTIN2 CD226 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12913096 19098271 22285893 26755705
NECTIN2 TIGIT â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12913096 19098271 22285893 26755705
PVR TIGIT â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12913096 16730454 18657862 19098271 19801517 22285893 24343663
PVR CD226 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12913096 16730454 18657862 19098271 19801517 22285893 24343663
PVR CD226 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12913096 15034010 15607800 21982860 30591568
NECTIN3 TIGIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1313846 26927206 21982860 30759143
TIGIT CD226 â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 22285893 22427644 25866972 26755705 26763253 27620276 28893624
CD4 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 PTPRC â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
GATA3 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24167278 19542428 23310955 19602726 20696860 24813204 18776904 20706986 20809492 20065998 19801513 21341258
CD4 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
CD274 PDCD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23417675 26681673 21422170 12893276 18841514 23954143 11015443 20587542 12719480 31757674 12889478 21982860 26602187
PDCD1LG2 PDCD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23417675 12893276 23954143 20587542 23223433 31727844 12810690
HLA-DQA2 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DRA PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
HLA-DQA1 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
PTPRC HLA-DPA1 â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
NLGN1 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18923512 9278515 30864948 11937501
HLA-DRA HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CTNNB1 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17785445 15473860 11326276 17335794 15728254
PTPRF CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10187801 9245795 11245482 12095414
CDH5 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18287330 17057644 12413882 20123964 23243000 21255999
CDH3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8227214 10381631 12800191 21255999 11889072
CTNNB1 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 16510874 23151663 11751639 15735151 17143293 16204248 23331499 12556497 21071413 14638683 15768032 18296023 12748295 21743491 11835406 16510875 18077326 8757136 9065403 20123964 15728254 17517646 21078818 15684397 8892228 10890911 15525529 12077367 9419974
SPTA1 SPTAN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22013193 19758564 24119662 19164740
HLA-A CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9177355 10809759
HLA-DQA1 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DPA1 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
ITGAL F11R â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 15681301 15528364 17525755 11812992
NTNG1 LRRC4C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21946559 1459544314595440 19467332 14595443
HLA-DQA1 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
SELPLG SELP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17145710 19118202 23994464 9128259 10713099 12393589 9129046 26627825 11081633 17064811 9829984
HLA-DOB HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DOA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DPA1 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
KCNQ2 KCNQ3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12890507 12524525 18827480 9836639
KCNQ3 KCNQ2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12890507 12524525 18827480 9836639
NLGN1 NRXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8576240 18923512 12796785 14522992
NLGN1 NRXN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18923512 8576240
NLGN1 NRXN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7736595 18923512
NTNG2 LRRC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25411505 17973922 21946559 19467332
NLGN3 NRXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18923512 8576240 9325340
NLGN3 NRXN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18923512 8576240 85762408576240
NLGN3 NRXN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18923512 8576240
SELPLG SELE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9024699 9128259 11402070 8621728 26124272
NLGN2 NRXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18923512 8576240 85762408576240
NLGN2 NRXN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18923512 8576240
NLGN2 NRXN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18923512 8576240