Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MFN2 PRKN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1231031 23620051
PRKN MFN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1231031 23620051
MFN2 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25915564 29921586
PRKN MFN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25915564 29921586
MARCHF5 MFN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219003 16936636
PPARG ESRRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20519122 15821111
ESRRA MFN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18974884 19448711
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TP53 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10749849 16713569
TP53 MFN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22510407 20804729
PINK1 PARK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 21179058 23725295
MAVS MARH5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21625535 32877691
MFN2 SAM50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27059175 29874585
VSIG1 GHITM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GHITM MFN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MFN1 MAVS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20661427 20019757
MAVS MFN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20661427 32877691
REEP5 MFN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VSIG1 MFN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MFN2 TCHP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29921586 20930847
PRKN2 TERA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 14532270 23503661 25959826 28514442
MFN2 AKAP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32877691 34079125
TERA MFN2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23498974 32877691 29676259
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
TERA HDAC6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18261755 27623077 11689694
S2546 MFN2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28057766 32877691
S2546 MFN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28057766 32877691
PRKN2 MFN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29921586 25915564 23503661 23620051 21615408 29676259 23060438 33356389 33730565
MARH5 MFN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26210454 26186194 23727017 28514442 32877691 16936636
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ESRRA PPARGC1A â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KLF4 SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12034813 22282354 16713569 9651398
MFN1 MFN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 19052620 27713096
PINK1 PRKN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23319602 19167501 22724072 24357652 27605430 23670163 25591737 28945249 19966284 20153330 17052189 33730565 20798600 19880420 26162776 26116755 23933751 19358826 27528605 32983119 19229105 29330382 25474007
ESRRA PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23668787 16213225 21625432
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
PPARD PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17084713 17275789 18509063
PPARD PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20097210 10991946 20176998
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
PPARGC1A ESRRA â—¼   UP_REGULATES ✅ + 0.93 0.93 Signor 18074631
MFN1 PARK2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MFN2 PARK2 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PPARG PPARGC1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PARK2 PINK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PINK1 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 93.0 1.0 Omnipath 25216678 27906179 19229105 26162776 25847540 29183391 26116755 33730565 26707701 25474007 25365205 25548534 25595529 29372317 24184327 25611507 22724072 20398440 26471730 28626500 29422536 27453777 24962176 24751536 26631732 22944659 17052189 25375667 25088558 33827825 27554669 24357652 24647965 24671417 29660402 30063295 27528605 23256036 29883688 23933751 23670163 23319602 25505445 25849928 23754282 20418918 19966284 25697646 32983119 30012094 34166935 29809156 24901221 28323427 25284222 29689231 30404819 19358826 19880420 20126261 26254304 20966070 29950828 20798600 29991771 24660806 30290272 25611391 25712550 29899409 28920079 25591737 29475881 29337137
PPARGC1A ESRRA â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16314495 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A ESRRA â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16314495 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A ESRRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12181319 18063693 15337744 12522104 32296183 18441008 15100410
PPARG FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19466435 18278065 15908479 16321227 14693716 12055599
SP1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15908479 16341057 9671487 1845987 8803927 2542772 7565693 15608673 9566920 1404598 2170405 10421838
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
KLF4 PPARG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
KLF4 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18511453 16244670 17308127 21132436 17659301
MAPK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 12356735 14665630 26158765 18778462 12969974 12861053 15254178 17135248 18669630 12384533 17363488 17698850 11283254 10706102 21454683 18931691 11551930 11397945 14612532 15064747 15963507 11175334 11423984 27147566 29234486 24657168 10581258 14517211 17353187 10673500 22030623 14527925 22728651 17525747 15629715 9393873 11447225 15671037 22285752 17245430 15140942 28673515 23871434 11078726 20041275 11896587 16731759 17121812 33514736 11861384 25431954 12810724 17967874 12955074 21832239 16818520 12756247 23798621 11526498 20009884 16713569 10202145 11850826 11896572 10710310 10570149 12959929 15269203 11583595 21148320
MAPK9 MFN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22748923
PINK1 MFN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 29971063 24328763 29674596 25132912 28190190 26992930 26611876
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
PPARG PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16513826 32991581 29182484
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368