Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PLEC AHCTF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AHCTF1 NUP160 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CDK2 MCM3AP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11526238
CRMP1 MCM3AP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MCM3AP ENY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMAD3 MCM3AP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 MCM3AP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MCM3AP NUDT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MCM3AP TMEM216 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MCM3AP PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NXF1 NUP214 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10668806 5212227
NXF1 NUP62 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10668806 5212227
SMAD9 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CDK2 MCM3 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 21965652
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CDK2 CDC25A â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 17110335
CDC25A CDK2 â—¼   DEPHOSPHORYLATION ✅ + 0.81 0.81 Signor 22263797
CETN1 CETN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 CETN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IER2 GLE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MCM3AP NXF1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
NXF1 RANBP2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
GLE1 NUP133 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MCM3AP PCID2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CDK2 MCM3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EP300 MCM3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33742100 30110629 20808282
CDC73 POLR2G â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
APC CDC42 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17145773 21311754
MCM3 CDK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 21965652 15232106
NUP133 NUP160 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
NUP107 NUP133 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
NXF1 GLE1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 29395067
PLRG1 RNF113A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SMAD3 SMAD9 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
NUP107 NXF1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NXF1 NUP98 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29395067 11073998 10668806 11551912 16713569 16314397 22334672
NUP133 NUP160 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PCNA CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10930425
BLM TERF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12181313 19329795 15229185
SMAD3 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21988832 15798217
MCM3AP CDC73 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRMP1 TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FAM118B MCM3AP â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TAF1D MCM3AP â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MCM3AP TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MCM3AP SUV39H2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NUP133 NUP107 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5219767 17363900
NUP133 NUP98 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NUP107 NUP160 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
NUP214 NXF1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CETN3 MCM3AP â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
NUP62 NXF1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
GLE1 NUP214 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
ENY2 MCM3AP â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
NUP160 NUP98 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
PCNA CDK2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 26496610 7903056 9545286 26186194 12361598 21319273 10930425 29510343
NUP98 NXF1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
NUP214 NUP62 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDK2 PCNA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NUP107 NUP160 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NUP107 NUP98 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NUP107 NUP133 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BLM PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
BLM TERF2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
TERF2 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 15229185 19329795 12181313
CDC25A CDK2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 1075565 15279786 17303408 17568790 17660363 18073536 18590585 18786381 7575488
CDC25A CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8617791 11602341 17303408 18073536 1075565 15279786 7575488 10454565 11154267 12411508 16189514 1396589 18590585 18786381 17660363 12388094 22263797 27485204 17568790 15659558
CDK2 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10197981 11283614 12193595 14536078 15147722 15241418 15279786 16156666 17055429 17303408 17660363 18590585 18636226 20027199 20713526 2191300 28536364 7575488
CDK2 MCM3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21106439 19652536 7575488 18590585 17522590 17303408 27035875 19473886 24948874 15677884 15279786 23029264 19124971 17660363 17038621 20148668
CDK2 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7575488 18590585 17296725 17303408 21965652 30062004 17102137 17116885 19793801 17582221 15232106 16189514 17660363 15279786
CDK2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 10197981 15241418 19218245 25241761 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 15212693 19114991
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
SMAD3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18391971 15084259
MCM3AP MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9712829 11024281 12226073 10733502
NUP214 NXF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11551912 11073998 10668806 16713569 10228171
NUP214 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 12917407
NUP98 NXF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22334672 10668806 16713569