CDK2
|
MCM3AP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11526238
|
MCM3AP
|
ENY2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SMAD3
|
MCM3AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
CRMP1
|
MCM3AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MCM3AP
|
NUDT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SMAD9
|
MCM3AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
MCM3AP
|
TMEM216
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MCM3AP
|
PLEC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SMAD9
|
PLEC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
CDK2
|
MCM3
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
21965652
|
EP300
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CDK2
|
CDC25A
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.81
|
0.81
|
Signor
|
17110335
|
CDC25A
|
CDK2
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.81
|
0.81
|
Signor
|
22263797
|
CETN1
|
CETN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CETN1
|
CETN3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CETN1
|
PCID2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MCM3AP
|
NXF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
EP300
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
MCM3AP
|
PCID2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
CDK2
|
MCM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
EP300
|
MCM3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20808282
30110629
33742100
|
APC
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17145773
21311754
|
MCM3
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15232106
16189514
21965652
|
EP300
|
FOXO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15890677
24419059
25609649
18786403
11896584
|
EP300
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9679056
15824515
15688032
16109717
15345715
20564330
9843571
15133024
10497242
17469184
15623506
10575014
15588252
18055455
16876108
21567395
11134049
12743039
11058129
|
CDC73
|
POLR2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
SMAD3
|
SMAD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
15231748
33961781
26186194
|
SMAD3
|
SMAD9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
CDC42
|
RAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31871319
9427749
|
BLM
|
TERF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12181313
19329795
15229185
|
SMAD3
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21988832
15798217
|
CDK2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26186194
10330164
23455922
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
EP300
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11268218
16713569
18263614
12937166
24939902
14988403
33742100
|
MCM3AP
|
CDC73
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CRMP1
|
TSC22D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TAF1D
|
MCM3AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
FAM118B
|
MCM3AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MCM3AP
|
SUV39H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MCM3AP
|
TSC22D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CETN3
|
MCM3AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
EP300
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
PCNA
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12361598
28514442
26496610
29510343
9545286
33961781
26186194
7903056
21319273
10930425
|
ENY2
|
MCM3AP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
BLM
|
PCNA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
16697054
18931676
19622404
19686080
19772495
19847258
22266823
22657828
22973052
23253856
24089143
24095737
|
BLM
|
TERF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
16697054
18931676
19622404
19686080
19772495
19847258
22266823
22657828
23253856
24089143
24095737
|
TERF2
|
BLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
15229185
19329795
12181313
|
CDC25A
|
CDK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
1075565
15279786
17303408
17568790
17660363
18073536
18590585
18786381
7575488
|
CDC25A
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
8617791
11602341
17303408
18073536
1075565
15279786
7575488
10454565
11154267
12411508
16189514
1396589
18590585
18786381
17660363
12388094
22263797
27485204
17568790
15659558
|
CDK2
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10197981
11283614
12193595
14536078
15147722
15241418
15279786
16156666
17055429
17303408
17660363
18590585
18636226
20027199
20713526
2191300
28536364
7575488
|
CDK2
|
MCM3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
10197981
15241418
19218245
25241761
15520018
20068231
17099224
16156666
16189514
19413330
14512875
12193595
15212693
19114991
|
CDK2
|
MCM3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
7575488
18590585
17296725
17303408
21965652
30062004
17102137
17116885
19793801
17582221
15232106
16189514
17660363
15279786
|
CDK2
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
21106439
19652536
7575488
18590585
17522590
17303408
27035875
19473886
24948874
15677884
15279786
23029264
19124971
17660363
17038621
20148668
|
PCNA
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18263614
11268218
16713569
|
EP300
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9843571
11134049
12743039
15133024
15824515
15623506
16876108
21567395
16109717
17074756
20564330
10497242
15588252
17469184
15345715
11058129
10575014
16862174
|
SMAD3
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18391971
15084259
|
MCM3AP
|
MCM3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9712829
11024281
12226073
10733502
|